The incomplete kawasaki disease in child three moths old with formation of aneurysms of coronary and peripheral arteries


The Kawasaki disease is a systemic vasculitis of unclear etiology extremely rare occurring in children of the first three months of life. The disease often takes course in incomplete and atypical form and brings high risk of development of such cardio-vascular diseases as aneurysms of coronary and peripheral arteries. The disease progresses in acute form with fever, catarrhal manifestations and results in convalescence and hence it is very often considered as infection pathology. Nowadays, there is no specific diagnostic tests permitting verifying the disease. The article presents clinical case of Kawasaki disease in child of three months age who was not diagnosed timely. As result, up to nine months in boy aneurysms of coronary and axillary arteries were developed. This observation emphasizes complexity of diagnostic of Kawasaki disease in children of early age, absence of diagnostic criteria and high risk of development of aneurysms of arteries under incomplete and/or atypical forms, especially in children prior to age of three months.

Full Text

Restricted Access

About the authors

Elena M. Kamaltynova

The Siberian state medical university of Minzdrav of Russia; The Tomsk Oblastnaia children hospital

634050, Tomsk, Russia
MD, PhD, DSc. Associate professor Department of faculty pediatrics with children diseases course of general practice faculty «Siberian State Medical University»; Deputy Chief Doctor The Tomsk Region Children Hospital

D. R Tukhvatulina

The Tomsk Oblastnaia children hospital

634009, Tomsk, Russia

V. A Rovitskaya

The Siberian state medical university of Minzdrav of Russia

634050, Tomsk, Russia

E. G Belonogova

The Siberian state medical university of Minzdrav of Russia; The Tomsk Oblastnaia children hospital

634009, Tomsk, Russia

E. A Karbainova

The Tomsk Oblastnaia children hospital

634009, Tomsk, Russia

V. V Saushkin

The research institute of cardiology

634012 Tomsk, Russia

T. P Kondratyeva

The research institute of cardiology

634012 Tomsk, Russia


  1. Kawasaki T. Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in children. Arerugi. 1967; 16 (3): 178-222.
  2. Лыскина Г.А. Клиника и диагностика слизисто-кожного лимфонодулярного синдрома (синдрома Кавасаки). Доктор.Ру. 2009; 1: 13-8.
  3. Солдатова Т.А., Брегель Л.В., Субботин В.М., Логинова М.С., Мутина А.Н. Болезнь Кавасаки - актуальная причина приобретенных заболеваний сердца у детей в мире. Сибирский медицинский журнал (Иркутск). 2010; 97 (6): 5-8.
  4. Брегель Л.В., Субботин В.М. Клинические и эхокардио-кардиографические проявления коронарита при болезни Кавасаки у детей: Руководство для врачей. Иркутск: РИО ИГИУВа; 2006.
  5. Гедике Г., Хотама П.Д., Хайнкинг Б. Болезнь Кавасаки - новые данные. Вопросы современной педиатрии. 2010; 9 (1): 104-15.
  6. Newburger J.W., Takahashi M., Gerber M.A., Gewitz M.H., Tani L.Y., Burns J.C. et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Pediatrics. 2004; 114 (6): 1708-33.
  7. Liu H.C., Lo C.W., Hwang B., Lee P.C. Clinical manifestations vary with different age spectrums in infants with Kawasaki disease. Scientific World Journal. 2012; 2012: 210382.
  8. Leonardi S., Barone P., Gravina G., Parisi G.F., Di Stefano V., Sciacca P. et al. Severe Kawasaki disease in a 3-month-old patient: a case report. BMC Res. Notes. 2013: 6: 500.
  9. Kuwabara M., Yashiro M., Kotani K., Tsuboi S., Ae R., Nakamura Y. et al. Cardiac lesions and initial laboratory data in Kawasaki disease: a nationwide survey in Japan. J. Epidemiol. 2015; 25 (3): 189-93.
  10. Jin B., Feng X.Y. Dual-source CT imaging of multiple giant coronary and axillary aneurysms in a child with Kawasaki disease. Eur. Rev. Med. Pharmacol. Sci. 2014; 18 (14): 1969-72.
  11. Волгина С.Я. Синдром Кавасаки у детей. Вестник современной клинической медицины. 2013; 6 (3): 86-91.
  12. Лукушкина Е.Ф., Костарева Т.Ю., Азовцева И.А., Квасова М.А., Афраймович М.Г. Клинический случай диагностики болезни Кавасаки у детей. Медицинский альманах. 2010; 2 (11): 144-6.
  13. Кожухова Ж.В., Иванова О.Н., Устюжина Т.В. Наблюдение клинического случая болезни Кавасаки. Наука и образование. 2014; 2: 91-4.
  14. Vinding R.K., Debes N.M., Stantchev H., Vrang C., Orngreen M.C. Incomplete Kawasaki syndrome with a coronary artery aneurysm in an infant. Ugeskr. Laeger. 2014; 176 (25).
  15. Seaton K.K., Kharbanda A. Evidence-based management of Kawasaki disease in the emergency department. Pediatr. Emerg. Med. Pract. 2015; 12 (1): 1-20.
  16. Falcini F., Ozen S., Magni-Manzoni S., Candelli M., Ricci L., Martini G. et al. Discrimination between incomplete and atypical Kawasaki syndrome versus other febrile diseases in childhood: results from an international registry-based study. Clin. Exp. Rheumatol. 2012; 30 (5): 799-804.
  17. Berdej-Szczot E., Firek-Pędras M., Szydłowski L., Krzystolik-Ładzińska J., Klimek K., Małecka-Tendera E. Analysis of risk factors and prospective evaluation of cardiovascular complications of Kawasaki disease in children: a single centre study. Kardiol. Pol. 2013; 71 (12): 1279-86.



Abstract - 46

PDF (Russian) - 0


Article Metrics

Metrics Loading ...


  • There are currently no refbacks.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies