Russian MedicineRussian Medicine0869-21062412-9100Eco-Vector3790410.17816/rmj37904The structural and functional state of the thyroid during physiological pregnancyStryukR I-KusovaAlla Borisovnaa_kusova@mail.ruMkrtumyanA M-StryukR I-KusovaA B-MkrtumyanA M-15042011172202221072020Copyright © 2011, Eco-Vector2011The structural and functional state of the thyroid was studied from ultrasonographic findings, the levels of triiodothyronine, thyroxine and thyroid-stimulating hormone in 45 pregnant women in the second and three trimesters of pregnancy and in 25 non-pregnant women, whose age was 18-45 years. As compared to the controls, the group of pregnant women showed a significant increase in thyroid volume, an elevation of the levels of all the study thyroid hormones, and a reduction in thyroid-stimulating hormone, which did not exceed the reference limit. These thyroid structural and functional changes are regarded as metabolic rearrangement-induced physiological gestational ones in a pregnant woman.thyroidthyroid statuspregnancyщитовидная железатиреоидный статусбеременность[Древаль А. В., Шестакова Т. П., Нечаева О. А. // Качество жизни. Медицина. - 2006. - № 3. - С. 34-39.][Клименко Н. И., Малясова С. В., Мельниченко Г. А., Мурашко Л. Е. // Рус. мед. журн. - 1998. - № 3.][Теппермен Дж., Теппермен Х. Физиология обмена веществ и эндокринной системы: Пер. с англ. - М., 1989. - С. 274-314.][Фадеев В. В., Мельниченко Г. А. // Гинекология. - 2001. - Т. 3, № 5. - С. 191-194.][Фадеев В. В., Мельниченко Г. А. Гипотиреоз: Руководство для врачей. - М., 2002.][Фадеев В. В., Лесникова С. В., Мельниченко Г. А. // Пробл. эндокринол. - 2003. - № 5.][Brent G. A. // Thyroid. - 1998. - Vol. 99. - P. 331-334.][Inzucchi S. E., Burrov G. N. // Reproductive Endocrinology, Philadelphia, 1999. - P. 413-435.][Stockigt J. R. // Endocrinol. Metab. Clin. N. Am. - 2001. - Vol. 30. - P. 265-268.]