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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Vestnik of the Far East Branch of the Russian Academy of Sciences</journal-id><journal-title-group><journal-title xml:lang="en">Vestnik of the Far East Branch of the Russian Academy of Sciences</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Дальневосточного отделения Российской академии наук</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0869-7698</issn><publisher><publisher-name xml:lang="en">The Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">676019</article-id><article-id pub-id-type="doi">10.31857/S0869769824010022</article-id><article-id pub-id-type="edn">lexhkq</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>To the 300th anniversary of the Russian Academy of Sciences</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>К 300‑летию Российской академии наук</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">G. B. Elyakov Pacific Institute of Bioorganic Chemistry – scientific results and research prospects</article-title><trans-title-group xml:lang="ru"><trans-title>Тихоокеанский институт биоорганической химии им. Г. Б. Елякова ДВО РАН: научные результаты и перспективы исследований</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4416-7844</contrib-id><name-alternatives><name xml:lang="en"><surname>Dmitrenok</surname><given-names>Pavel S.</given-names></name><name xml:lang="ru"><surname>Дмитренок</surname><given-names>Павел Сергеевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Doctor of Sciences in Chemistry, Director</p></bio><bio xml:lang="ru"><p>доктор химических наук, директор</p></bio><email>paveldmt@piboc.dvo.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6572-8575</contrib-id><name-alternatives><name xml:lang="en"><surname>Borisova</surname><given-names>Kseniya L.</given-names></name><name xml:lang="ru"><surname>Борисова</surname><given-names>Ксения Леонидовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Candidate of Sciences in Chemistry, Scientific Secretary</p></bio><bio xml:lang="ru"><p>кандидат химических наук, ученый секретарь</p></bio><email>science@piboc.dvo.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">G. B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS</institution></aff><aff><institution xml:lang="ru">Тихоокеанский институт биоорганической химии им. Г. Б. Елякова ДВО РАН</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-02-15" publication-format="electronic"><day>15</day><month>02</month><year>2024</year></pub-date><issue>1</issue><issue-title xml:lang="ru"/><fpage>17</fpage><lpage>38</lpage><history><date date-type="received" iso-8601-date="2025-02-28"><day>28</day><month>02</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Russian Academy of Sciences</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Российская академия наук</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Russian Academy of Sciences</copyright-holder><copyright-holder xml:lang="ru">Российская академия наук</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/0869-7698/article/view/676019">https://journals.eco-vector.com/0869-7698/article/view/676019</self-uri><abstract xml:lang="en"><p>In 2024, the Russian Academy of Sciences turns 300 years old, and G. B. Elyakov Pacific Institute of Bioorganic Chemistry (PIBOC FEB RAS) will celebrate 60th anniversary. PIBOC FEB RAS is an institute with a world reputation in the field of bioorganic chemistry, namely, the structural chemical biology of primary and secondary metabolites from marine and terrestrial organisms, molecular biology, including the study of the functions and biological activities and mechanisms of action of the studied natural compounds, molecular genetic research. The article presents the main scientific results of the leading laboratories of the institute in these promising scientific areas, mainly over the past five years.</p></abstract><trans-abstract xml:lang="ru"><p>В 2024 г. Российской академии наук исполняется 300 лет, а Тихоокеанский институт биоорганической химии им. Г. Б. Елякова Дальневосточного отделения Российской академии наук (ТИБОХ ДВО РАН) отпразднует свое 60-летие. ТИБОХ ДВО РАН является институтом с мировой репутацией в области биоорганической химии, а именно, структурно-химической биологии первичных и вторичных метаболитов из морских и наземных организмов, молекулярной биологии, в том числе изучения функций и биологических активностей и механизмов действия исследуемых природных соединений, молекулярно-генетических исследований. В статье представлены основные результаты работ ведущих лабораторий института по этим перспективным научным направлениям преимущественно за последние пять лет научных исследований.</p></trans-abstract><kwd-group xml:lang="en"><kwd>PIBOC</kwd><kwd>scientific achievements</kwd><kwd>scientific directions</kwd><kwd>natural compounds</kwd><kwd>structures</kwd><kwd>biological activity</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ТИБОХ</kwd><kwd>научные достижения</kwd><kwd>научные направления</kwd><kwd>природные соединения</kwd><kwd>структуры</kwd><kwd>биологическая активность</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Guzii A. G., Makarieva T. N., Denisenko V. A., Gerasimenko A. V., Udovenko A. A., Popov R. S., Dmitrenok P. S., Golotin V. A., Fedorov S. N., Grebnev B. B., Stonik V. A. 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