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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">N.N. Priorov Journal of Traumatology and Orthopedics</journal-id><journal-title-group><journal-title xml:lang="en">N.N. Priorov Journal of Traumatology and Orthopedics</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник травматологии и ортопедии им. Н.Н. Приорова</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0869-8678</issn><issn publication-format="electronic">2658-6738</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">112134</article-id><article-id pub-id-type="doi">10.17816/vto112134</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original study articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Aspects of vertebral column resection in patients with rigid kyphotic and kyphoscoliotic deformities of different genesis of the thoracolumbar spine: multicenter retrospective observational cohort study</article-title><trans-title-group xml:lang="ru"><trans-title>Особенности выполнения резекции позвоночного столба по поводу ригидных кифотических и кифосколиотических деформаций грудопоясничного отдела позвоночника различного генеза: мультицентровое ретроспективное наблюдательное когортное исследование</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8938-2321</contrib-id><contrib-id contrib-id-type="spin">7686-2123</contrib-id><name-alternatives><name xml:lang="en"><surname>Gorbatyuk</surname><given-names>Dmitry S.</given-names></name><name xml:lang="ru"><surname>Горбатюк</surname><given-names>Дмитрий Сергеевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Traumatologist-Orthopedist</p></bio><bio xml:lang="ru"><p>врач травматолог-ортопед</p></bio><email>naddis@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9657-8584</contrib-id><contrib-id contrib-id-type="spin">1989-6994</contrib-id><name-alternatives><name xml:lang="en"><surname>Kolesov</surname><given-names>Sergey V.</given-names></name><name xml:lang="ru"><surname>Колесов</surname><given-names>Сергей Васильевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Traumatologist-Orthopedist, Department Head</p></bio><bio xml:lang="ru"><p>д.м.н., заведующий отделением, врач травматолог-ортопед</p></bio><email>dr-kolesov@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8884-2410</contrib-id><name-alternatives><name xml:lang="en"><surname>Shvets</surname><given-names>Vladimir V.</given-names></name><name xml:lang="ru"><surname>Швец</surname><given-names>Владимир Викторович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Leading Researcher, Traumatologist-Orthopedist</p></bio><bio xml:lang="ru"><p>д.м.н., ведущий научный сотрудник, врач травматолог-ортопед</p></bio><email>vshvecv@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7448-3904</contrib-id><contrib-id contrib-id-type="spin">4593-3231</contrib-id><name-alternatives><name xml:lang="en"><surname>Morozova</surname><given-names>Nataliya S.</given-names></name><name xml:lang="ru"><surname>Морозова</surname><given-names>Наталия Сергеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.), Traumatologist-Orthopedist</p></bio><bio xml:lang="ru"><p>к.м.н., врач травматолог-ортопед</p></bio><email>morozcito@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5765-3158</contrib-id><contrib-id contrib-id-type="spin">7678-6542</contrib-id><name-alternatives><name xml:lang="en"><surname>Ptashnikov</surname><given-names>Dmitry A.</given-names></name><name xml:lang="ru"><surname>Пташников</surname><given-names>Дмитрий Александрович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor, Scientific Head of the Department, Traumatologist-Orthopedist</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, научный руководитель отделения, врач травматолог-ортопед</p></bio><email>drptashnikov@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6310-4961</contrib-id><contrib-id contrib-id-type="spin">9803-0387</contrib-id><name-alternatives><name xml:lang="en"><surname>Mlyavykh</surname><given-names>Sergey O.</given-names></name><name xml:lang="ru"><surname>Млявых</surname><given-names>Сергей Олегович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Associate Professor</p></bio><bio xml:lang="ru"><p>д.м.н., доцент</p></bio><email>spinedoc@bk.ru</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1630-7053</contrib-id><contrib-id contrib-id-type="spin">2047-0881</contrib-id><name-alternatives><name xml:lang="en"><surname>Bratsev</surname><given-names>Ivan S.</given-names></name><name xml:lang="ru"><surname>Братцев</surname><given-names>Иван Семенович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Neurosurgeon</p></bio><bio xml:lang="ru"><p>врач-нейрохирург</p></bio><email>spinedoc@bk.ru</email><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Priorov National Medical Research Center for Traumatology and Orthopedics</institution></aff><aff><institution xml:lang="ru">НМИЦ травматологии и ортопедии им. Н.Н. Приорова</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Vreden National Medical Research Center for Traumatology and Orthopedics</institution></aff><aff><institution xml:lang="ru">НМИЦ травматологии и ортопедии им. Р.Р. Вредена</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Privolzhsky Research Medical University</institution></aff><aff><institution xml:lang="ru">Приволжский исследовательский медицинский университет</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2023-01-20" publication-format="electronic"><day>20</day><month>01</month><year>2023</year></pub-date><pub-date date-type="pub" iso-8601-date="2022-09-15" publication-format="electronic"><day>15</day><month>09</month><year>2022</year></pub-date><volume>29</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>237</fpage><lpage>248</lpage><history><date date-type="received" iso-8601-date="2022-10-27"><day>27</day><month>10</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-12-06"><day>06</day><month>12</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Gorbatyuk D.S., Kolesov S.V., Shvets V.V., Morozova N.S., Ptashnikov D.A., Mlyavykh S.O., Bratsev I.S.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, Горбатюк Д.С., Колесов С.В., Швец В.В., Морозова Н.С., Пташников Д.А., Млявых С.О., Братцев И.С.</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Gorbatyuk D.S., Kolesov S.V., Shvets V.V., Morozova N.S., Ptashnikov D.A., Mlyavykh S.O., Bratsev I.S.</copyright-holder><copyright-holder xml:lang="ru">Горбатюк Д.С., Колесов С.В., Швец В.В., Морозова Н.С., Пташников Д.А., Млявых С.О., Братцев И.С.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2024-02-27"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0/</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.eco-vector.com/0869-8678/article/view/112134">https://journals.eco-vector.com/0869-8678/article/view/112134</self-uri><abstract xml:lang="en"><p><bold><italic>BACKGROUND</italic></bold><italic>: </italic>Vertebral column resection (VCR) as a type of spinal osteotomy is characterized by maximum possibilities of three-dimensional correction of various etiologies: congenital, post-tuberculous, iatrogenic (after other interventions on the spine), degenerative, and vertebral spondyloptosis caused by Kümmel’s disease, and primary, and metastatic tumor lesions of the spine. Nowadays, the use of single-level VCR is far beyond its initial purpose.</p> <p><bold><italic>OBJECTIVE</italic></bold><italic>:</italic> The study aimed to compare features of VCR for rigid deformities of various etiologies and management of erythrocyte blood products in the perioperative period.</p> <p><bold><italic>MATERIALS AND METHODS</italic></bold><italic>:</italic> A multicenter retrospective observational cohort study analyzed data from 53 adult (aged ≥18 years) patients with kyphotic and kyphoscoliotic deformities of the thoracic and lumbar spine, distributed into four comparison groups according to the deformity genesis, namely, impaired spinal development, traumatic genesis, degenerative or idiopathic, and neoplasms of the vertebral bodies. The characteristics of VCR in these patients were compared.</p> <p><bold><italic>RESULTS</italic></bold><italic>: </italic>The surgery duration was longer in VCR for spinal neoplasms (<italic>p</italic> &lt;0.05) than for high-energy burst compression fractures of vertebral bodies and scoliotic deformities (grade IV). On average, this group also had the most cranial osteotomy level among the study groups. VCR for idiopathic scoliotic deformities is characterized by a larger intraoperative blood loss volume than other nosologies, and the differences were statistically significant. In male patients of this group, the hemoglobin level on day 1 after surgery was statistically significantly lower than in those who underwent VCR for compression fractures of the vertebral bodies or impaired vertebral development. During resection of the vertebral column for burst compression fractures of the vertebral bodies, the fixation length was less (<italic>p </italic>&lt;0.05), with a similar intervention for developmental anomalies, deformities of postoperative genesis, and grade IV idiopathic scoliosis. VCR for grade IV idiopathic scoliosis requires a larger (<italic>p</italic> &lt;0.05) volume of the reinfused autologous blood than for intervention for acute traumatic pathologies (burst compression fractures of the vertebral bodies).</p> <p><bold><italic>CONCLUSION</italic></bold><italic>: </italic>The versatility of clinical tasks for which resection of the spinal column can be performed using the VCR technique also determines the significant heterogeneity of the patients who undergo such treatment. Knowledge of the interventions in various nosologies is very useful in vertebrological practice.</p></abstract><trans-abstract xml:lang="ru"><p><bold><italic>Обоснование</italic></bold><italic>.</italic> Резекция позвоночного столба (vertebral column resection, VCR) как вид остеотомии позвоночника характеризуется максимальными возможностями трёхмерной коррекции различного генеза: врождённого, посттуберкулёзного, ятрогенного (после иных вмешательств на позвоночнике), дегенеративного, а также при спондилоптозе позвонка, обусловленном болезнью Кюммеля, и при первичных и метастатических опухолевых поражениях позвоночника. К настоящему моменту применение VCR вышло далеко за рамки своего первоначального предназначения.</p> <p><bold><italic>Цель</italic></bold><italic>. </italic>Сравнить особенности выполнения VCR по поводу ригидных деформаций различной этиологии, а также менеджмента эритроцитарных препаратов крови в периоперационном периоде.</p> <p><bold><italic>Материалы и методы</italic></bold><italic>.</italic> Мультицентровое ретроспективное наблюдательное когортное исследование проведено на основе данных 53 взрослых (≥18 лет) пациентов с кифотическими и кифосколиотическими деформациями грудного и поясничного отдела позвоночника, разделённых на 4 группы сравнения по генезу деформации: аномалии развития позвоночника, травматический генез, дегенеративный либо идиопатический кифосколиоз, новообразования тел позвонков.</p> <p><bold><italic>Результаты</italic></bold><italic>. </italic>При выполнении VCR по поводу новообразований позвоночника длительность операции оказалась выше, чем при VCR по поводу высокоэнергетических «взрывных» компрессионных переломов тел позвонков и сколиотических деформаций IV степени (<italic>p</italic> &lt;0,05). Дополнительно эта группа характеризуется в среднем наиболее краниальным значением уровня остеотомии среди групп пациентов, участвовавших в исследовании. VCR по поводу идиопатических сколиотических деформаций отличается большим объёмом интраоперационной кровопотери, чем иные рассмотренные в исследовании нозологии (различия также носят статистически значимый характер). Кроме того, у пациентов-мужчин этой группы уровень гемоглобина на 1-е сут после вмешательства статистически значимо ниже, чем у пациентов, которым VCR выполняли по поводу компрессионных переломов тел позвонков, либо деформации, вызванной аномалией развития позвонка. При VCR по поводу «взрывных» компрессионных переломов тел позвонков протяжённость фиксации меньше, чем при аналогичном вмешательстве по поводу аномалий развития и деформаций постоперационного генеза, а также идиопатического сколиоза IV степени (<italic>p</italic> &lt;0,05). При выполнении VCR по поводу идиопатического сколиоза IV степени требуется больший (<italic>p</italic> &lt;0,05) объём реинфузированной аутокрови, чем при вмешательстве по поводу острой травматической патологии («взрывных» компрессионных переломах тел позвонков).</p> <p><bold><italic>Заключение</italic></bold><italic>. </italic>Универсальность клинических задач, при которых может быть выполнена резекция позвоночного столба по методике VCR, обусловливает и значительную гетерогенность групп пациентов, которым проводится такое лечение. Знание особенностей выполнения вмешательств по поводу ригидных кифотических и кифосколиотических деформаций различного генеза имеет ценность в вертебрологической практике.</p></trans-abstract><kwd-group xml:lang="en"><kwd>vertebral column resection</kwd><kwd>intraoperational blood loss</kwd><kwd>hemoglobin</kwd><kwd>spine surgery</kwd><kwd>spine trauma</kwd><kwd>spine neoplasm</kwd><kwd>compression fracture</kwd><kwd>kyphoscoliotic deformity</kwd><kwd>kyphotic deformity</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>резекция позвоночного столба</kwd><kwd>интраоперационная потеря крови</kwd><kwd>гемоглобин</kwd><kwd>хирургия позвоночника</kwd><kwd>травма позвоночного столба</kwd><kwd>новообразования позвоночного столба</kwd><kwd>компрессионный перелом</kwd><kwd>кифосколиотическая деформация</kwd><kwd>кифотическая деформация</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">MacLennan A. 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