N.N. Priorov Journal of Traumatology and OrthopedicsN.N. Priorov Journal of Traumatology and Orthopedics0869-86782658-6738Eco-Vector4750210.17816/vto20130265-68Short CommunicationRevision Total Knee Arthroplasty due to Allergic Reaction to CobaltZagorodniyN. V-BukhtinK. Mk.bouhtin@gmail.comKudinovO. A-ChragyanG. A-BerchenkoG. N-NikolaevI. A-15062013202656820102020Copyright © 2013, Eco-Vector2013Clinical observation of patient undergone two revisions total knee arthroplasty was presented. The cause of revisions was clinical manifestation of inflammatory but no classic signs of infection were detected intraoperatively. Cupping of inflammatory was succeeded after insertion of implant coating by nitride ceramics. Possible inflammatory development as allergic reaction to cobalt was discussed.revision arthroplastymetal hypersensitivitycobalt allergyревизионное эндопротезированиегиперсенсибилизация на металлаллергия на кобальт[Basketter D.A., Briatico-Vangosa G., Kaestner W., Lally C., Bontinck W.J. Nickel, cobalt and chromium in consumer products: a role in allergic contact dermatitis. Contact Dermatitis. 1993; 28: 15-25.][Cramers M., Lucht U. Metal sensitivity in patients treated for tibial fractures with plates of stainless steel. Acta Orthop. Scand. 1977; 48: 245-9.][Fisher A.A. Allergic dermatitis presumably due to metallic foreign bodies containing nickel or cobalt. Cutis. 1977; 19: 285-6.][Gawkrodger D.J. Nickel sensitivity and the implantation of orthopaedic prostheses. Contact Dermatitis. 1993; 28: 257-9.][Haudrechy P., Foussereau J., Mantout B., Baroux B. Nickel release from nickel-plated metals and stainless steels. Contact Dermatitis. 1994; 31 (4): 249-55.][Huber J., Refior H, J. wear test, Ludwig MaximiliansUniversität München Labor für Biomechanik und Experimentelle Orthopädie, Germany, 2002 data on file.][Kanerva L., Sipilainen-Malm T., Estlander T., Zitting A., Jolanki R., Tarvainen K. Nickel release from metals, and a case of allergic contact dermatitis from stainless steel. Contact Dermatitis. 1994; 31: 299-303.][Merritt K., Rodrigo J.J. Immune response to synthetic materials. Sensitization of patients receiving orthopaedic implants. Clin. Orthop. 1996; 326: 71-9.]