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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">N.N. Priorov Journal of Traumatology and Orthopedics</journal-id><journal-title-group><journal-title xml:lang="en">N.N. Priorov Journal of Traumatology and Orthopedics</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник травматологии и ортопедии им. Н.Н. Приорова</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0869-8678</issn><issn publication-format="electronic">2658-6738</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">48088</article-id><article-id pub-id-type="doi">10.17816/vto200916473-78</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Choice of Antibacterial Agents for Prevention and Treatment of Infectious Complications in Traumatologic and Orthopaedic Patients by Microbiologic Monitoring</article-title><trans-title-group xml:lang="ru"><trans-title>Выбор антибактериальных средств для профилактики и лечения инфекционных осложнений у травматолого-ортопедических больных на основе микробиологического мониторинга</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pkhakadze</surname><given-names>Tamara Yakovlevna</given-names></name><name xml:lang="ru"><surname>Пхакадзе</surname><given-names>Тамара Яковлевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор мед. наук, зав. лабораторией микробиологииТел./факс: 8 (499) 153-40-01; тел. 8 (499) 153-61-12; ЦИТО</p></bio><email>microlab_cito@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Okropiridze</surname><given-names>G G</given-names></name><name xml:lang="ru"><surname>Окропиридзе</surname><given-names>Г Г</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, старший науч. сотр; ЦИТО</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Malysheva</surname><given-names>E S</given-names></name><name xml:lang="ru"><surname>Малышева</surname><given-names>Э С</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-бактериолог; ЦИТО</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Pkhakadze</surname><given-names>T Ya</given-names></name><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Okropiridze</surname><given-names>G G</given-names></name><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Malysheva</surname><given-names>E S</given-names></name><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ЦИТО</institution></aff></aff-alternatives><aff id="aff2"><institution></institution></aff><pub-date date-type="pub" iso-8601-date="2009-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2009</year></pub-date><volume>16</volume><issue>4</issue><issue-title xml:lang="en">NO4 (2009)</issue-title><issue-title xml:lang="ru">ТОМ 16, №4 (2009)</issue-title><fpage>73</fpage><lpage>78</lpage><history><date date-type="received" iso-8601-date="2020-10-20"><day>20</day><month>10</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2009, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2009, ООО "Эко-Вектор"</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://journals.eco-vector.com/0869-8678/article/view/48088">https://journals.eco-vector.com/0869-8678/article/view/48088</self-uri><abstract xml:lang="en"><p>Etiologic structure of infectious complications in traumatologic and orthopaedic patients has been studied at CITO named after N.N. Priorov during the period from 2005 to 2007. Using modern agents and techniques 6799 samples from 3023 patients were studied. Resistance of pathogenic microorganisms to the wide spectrum of antibiotics including the drugs of last gene-ration was studied. Basing on the study results the protocols for the application of modern antibiotics including protected aminopeptides, cephalosporins of third-forth generation including the protected ones, glycopeptides, oxazolidinones, aminoglycosides, fluoroquinolones, carbape-nemones have been elaborated and introduced into clinical practice.</p></abstract><trans-abstract xml:lang="ru"><p>Изучена этиологическая структура инфекционных осложнений у травматолого-ортопедических больных, находившихся на лечении в ЦИТО в 2005-2007 гг. С помощью современных средств и методов бактериологического анализа исследовано 6799 образцов материала от 3023 больных. Изучена антибиотикорезистентность микроорганизмов-возбудителей инфекции к широкому спектру антибиотиков, в том числе к препаратам последних поколений. На основании результатов проведенного исследования разработаны и внедрены в практику схемы применения современных антибиотиков, относящихся к группам защищенных аминопенициллинов, цефалоспоринов третьего-четвертого поколений, включая защищенные, гликопептидов, оксазолидинонов, аминогликозидов, фторхинолонов, карбапенемов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>infectious complications</kwd><kwd>microbiologic diagnosis</kwd><kwd>antibiotic therapy and prevention</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>инфекционные осложнения</kwd><kwd>микробиологическая диагностика</kwd><kwd>антибиотикотерапия и профилактика</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Маловичко В.В., Огарев Е.В., Уразгильдеев З.И. и др. 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