N.N. Priorov Journal of Traumatology and OrthopedicsN.N. Priorov Journal of Traumatology and Orthopedics0869-86782658-6738Eco-Vector5447010.17816/vto54470Research ArticleAspects of surgical treatment in a petient with Isaac’s syndromeKoryshkovNikolay A.<p>PhD, associate professor</p>nik-koryshkov@yandex.ruhttps://orcid.org/0000-0003-4465-2660MikhailovaLyudmila K.<p>PhD, professor, traumatologist-orthopedist</p>uchsovet1@cito-priorov.ruKhodzhievArtur S.<p>Cand. Sci. (Med.), traumatologist-orthopedist</p>hoji6600i@yahoo.comLitvinovIgor I.<p>PhD, associate professor</p>litorthorus@mail.ruhttps://orcid.org/0000-0003-1135-4376Yaroslavl State Medical UniversityN.N. Priorov National Medical Research Center of Traumatology and OrthopedicsSTAR MED CENTER Clinic1503202128129340912202026012021Copyright © 2021, Eco-Vector2021<p>This article presents a clinical case demonstrating the correction treatment of the lower extremities in a patient with Issacs syndrome, as well as the results of ankle surgery and successful post-surgery rehabilitation. The high efficiency of surgery as a treatment method was confirmed.</p>Isaac’s syndromemyokymiacontracture of the ankle and foot jointscorrective resectionarthrodesisсиндром Исаакамиокимияконтрактура голеностопного сустава и суставов стопыкорригирующая резекцияартродез[Ponomarev VV. Redkie nevrologicheskie sindromy i bolezni: nablyudeniya iz praktiki. Saint Petersburg: Foliant; 2005. P. 41–48. (In Russ.)][Yakhno NN, editor. Bolezni nervnoi sistemy. Vol. 1. Moscow: Meditsina; 2005. P. 637–638. (In Russ.)][Dhand UK. Isaacs’s syndrome: clinical and electrophysiological response to gabapentin. Muscle Nerve. 2006;34(5):646–650. DOI: 10.1002/mus.20591][Luk’yanov MV, Khvorostina AV, Isaeva NA. Diagnosis and treatment of Isaac’s syndrome. Nevrologicheskii zhurnal. 2003;8(6):21–26. (In Russ.)][Ponomarev VV. Autoimmunnye zabolevaniya v nevrologii. Minsk: Belaruskaya navuka; 2010. P. 104–109. (In Russ.)][Meinck HM. Stiff-Man syndrome. In: Lang F, editor. Encyclopedia of molecular mechanisms of disease. Berlin: Springer; 2009. P. 540–542.][Dumitru D, editor. Electrodiagnostic medicine. St. Louis: Mosby; 1995. P. 501–503.][Falace A, Striano P, Manganelli F, et al. Inherited neuromyotonia: a clinical and genetic study of a family. Neuromuscul Disord. 2007;17(1):23–27. DOI: 10.1016/j.nmd.2006.09.014][Maddison P. Neuromyotonia. Clin Neurophysiol. 2006;117(10):2118–2127. DOI: 10.1016/j.clinph.2006.03.008][Panagariya A, Kumar H, Mathew V, Sharma B. Neuromyotonia: clinical profile of twenty cases from northwest India. Neurol India. 2006;54(4):382–386. DOI: 10.4103/0028-3886.28110]