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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">N.N. Priorov Journal of Traumatology and Orthopedics</journal-id><journal-title-group><journal-title xml:lang="en">N.N. Priorov Journal of Traumatology and Orthopedics</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник травматологии и ортопедии им. Н.Н. Приорова</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0869-8678</issn><issn publication-format="electronic">2658-6738</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">633743</article-id><article-id pub-id-type="doi">10.17816/vto633743</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Clinical case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические случаи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Surgical treatment of spinal deformities associated with neurological deficits using 3D modeling technologies</article-title><trans-title-group xml:lang="ru"><trans-title>Хирургическое лечение деформаций позвоночника, ассоциированных с неврологическим дефицитом, с применением технологий 3D-моделирования</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9526-8274</contrib-id><contrib-id contrib-id-type="spin">7052-0220</contrib-id><name-alternatives><name xml:lang="en"><surname>Kuleshov</surname><given-names>Alexander A.</given-names></name><name xml:lang="ru"><surname>Кулешов</surname><given-names>Александр Алексеевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>д-р мед. наук</p></bio><email>cito-spine@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1314-2887</contrib-id><contrib-id contrib-id-type="spin">1402-5186</contrib-id><name-alternatives><name xml:lang="en"><surname>Nazarenko</surname><given-names>Anton G.</given-names></name><name xml:lang="ru"><surname>Назаренко</surname><given-names>Антон Герасимович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), professor of RAS</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор РАН</p></bio><email>nazarenkoag@cito-priorov.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6689-5220</contrib-id><contrib-id contrib-id-type="spin">9690-5117</contrib-id><name-alternatives><name xml:lang="en"><surname>Vetrile</surname><given-names>Marchel S.</given-names></name><name xml:lang="ru"><surname>Ветрилэ</surname><given-names>Марчел Степанович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>vetrilams@cito-priorov.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0406-1997</contrib-id><contrib-id contrib-id-type="spin">2767-2429</contrib-id><name-alternatives><name xml:lang="en"><surname>Makarov</surname><given-names>Sergey N.</given-names></name><name xml:lang="ru"><surname>Макаров</surname><given-names>Сергей Николаевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>moscow.makarov@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-9832-316X</contrib-id><contrib-id contrib-id-type="spin">4015-8113</contrib-id><name-alternatives><name xml:lang="en"><surname>Militsa</surname><given-names>Igor M.</given-names></name><name xml:lang="ru"><surname>Милица</surname><given-names>Игорь Михайлович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD</p></bio><email>igor.milica@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2479-4381</contrib-id><contrib-id contrib-id-type="spin">9845-1251</contrib-id><name-alternatives><name xml:lang="en"><surname>Lisyansky</surname><given-names>Igor N.</given-names></name><name xml:lang="ru"><surname>Лисянский</surname><given-names>Игорь Николаевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>lisigornik@list.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Priorov National Medical Research Center of Traumatology and Orthopedics</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр травматологии и ортопедии им. Н.Н. Приорова</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2025-03-15" publication-format="electronic"><day>15</day><month>03</month><year>2025</year></pub-date><pub-date date-type="pub" iso-8601-date="2025-02-15" publication-format="electronic"><day>15</day><month>02</month><year>2025</year></pub-date><volume>32</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>161</fpage><lpage>172</lpage><history><date date-type="received" iso-8601-date="2024-06-24"><day>24</day><month>06</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-09-02"><day>02</day><month>09</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Эко-Вектор</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2026-04-08"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0/</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.eco-vector.com/0869-8678/article/view/633743">https://journals.eco-vector.com/0869-8678/article/view/633743</self-uri><abstract xml:lang="en"><p><bold>BACKGROUND:</bold><italic> </italic>Progressive spinal cord compression in spinal deformities leads to neurological deficit, creating a high risk of patient disability. Modern 3D modeling technologies allow for the production of individual implants and the creation of full-size models of the spine and spinal cord, which radically improves the approach to treating patients with severe spinal deformities. These technologies are especially effective in congenital anomalies, tumors, and post-traumatic defects, providing a better spatial representation of the pathology and the possibility of personalized surgical treatment of neurologically complicated spinal deformities.</p> <p><bold>CLINICAL CASES DESCRIPTION:</bold><bold> </bold>The results of two patients with kyphoscoliotic deformities of the spine combined with spinal cord compression using custom metal structures and 3D modelling capabilities are presented. Clinical examples show the choice of surgical tactics in the treatment of progressive kyphoscoliotic deformities leading to spinal cord compression. Methods of spinal cord decompression and surgical planning using individual full-size 3D models of the spine and spinal cord are presented, as well as the possibility and effectiveness of using individual plates to fix spinal deformities.</p> <p><bold>CONCLUSION:</bold><italic> </italic>Surgical treatment resulted in stable fixation of the deformity and regression of the neurological deficit, helping to prevent disability and restore functional activity.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование.</bold><bold> </bold>Прогрессирование компрессии спинного мозга при деформациях позвоночника приводит к неврологическому дефициту, создавая высокий риск инвалидизации пациентов. Современные технологии 3D-моделирования позволяют изготавливать индивидуальные имплантаты и создавать полноразмерные модели позвоночника и спинного мозга, что радикально улучшает подход к лечению пациентов с тяжёлыми деформациями позвоночника. Эти технологии особенно эффективны при врождённых аномалиях, опухолях и посттравматических дефектах, обеспечивая лучшее пространственное представление патологии и возможность персонализированного хирургического лечения неврологически осложнённых деформаций позвоночника.</p> <p><bold>Описание клинических случаев.</bold><bold> </bold>Представлены результаты хирургического лечения двоих пациентов с кифосколиотическими деформациями позвоночника в сочетании с компрессией спинного мозга с применением индивидуальных металлоконструкций и возможностей 3D-моделирования. На клинических примерах показан выбор хирургической тактики при лечении прогрессирующих кифосколиотических деформаций, которые привели к компрессии спинного мозга. Представлены методы декомпрессии спинного мозга и планирования хода операции с использованием индивидуальных полноразмерных 3D-моделей позвоночника и спинного мозга, а также возможность и эффективность применения индивидуальных пластин для фиксации деформации позвоночника.</p> <p><bold>Заключение.</bold><bold> </bold>В результате хирургического лечения достигнуты стабильная фиксация деформации и регресс неврологического дефицита, что способствовало предотвращению инвалидизации пациентов и восстановлению их функциональной активности.</p></trans-abstract><kwd-group xml:lang="en"><kwd>kyphosis</kwd><kwd>scoliosis</kwd><kwd>neurological deficit</kwd><kwd>decompression</kwd><kwd>3D modeling</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>кифоз</kwd><kwd>сколиоз</kwd><kwd>неврологический дефицит</kwd><kwd>декомпрессия</kwd><kwd>3D-моделирование</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Goel SA, Neshar AM, Chhabra HS. A rare case of surgically managed multiple congenital thoraco-lumbar and lumbar block vertebrae with kypho-scoliosis and adjacent segment disease with myelopathy in a young female. Journal of Clinical Orthopaedics and Trauma. 2020;11(2):291–294. doi: 10.1016/j.jcot.2019.04.017</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Matee S, Ayaz SB, Bashir U. Progressive thoracic kyphoscoliosis leading to paraplegia in a child with neurofibromatosis type- 1. Journal of the College of Physicians and Surgeons Pakistan. 2021;31(1):98–100. doi: 10.29271/jcpsp.2021.01.98</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Katiyar P, Boddapati V, Coury J, et al. Three-Dimensional Printing Applications in Pediatric Spinal Surgery: A Systematic Review. Global spine journal. 2024;14(2):718–730. doi: 10.1177/21925682231182341</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Senkoylu A, Daldal I, Cetinkaya M. 3D printing and spine surgery. Journal of orthopaedic surgery (Hong Kong). 2020;28(2):2309499020927081. doi: 10.1177/2309499020927081</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Singh K, Samartzis D, An HS. Neurofibromatosis type I with severe dystrophic kyphoscoliosis and its operative management via a simultaneous anterior-posterior approach: A case report and review of the literature. Spine Journal. 2005;5(4):461–466. doi: 10.1016/j.spinee.2004.09.015</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Sugimoto Y, Ito Y, Tanaka M, et al. Cervical cord injury in patients with ankylosed spines: progressive paraplegia in two patients after posterior fusion without decompression. Spine. 2009;34(23):E861–3. doi: 10.1097/BRS.0b013e3181bb89fc</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Maxwell AKE. Spinal cord traction producing an ascending, reversible, neurological deficit. Case report. Verhandlungen der Anatomischen Gesellschaft. 1967;(115):49–69.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Ransohoff J, et al. Spinal Cord Traction Producing an Ascending, Reversible, Neurological Deficit. Case Reports. 1969;(31):459–461.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Breig A, Braxton V. Biomechanics of the central nervous system: some basic normal and pathologic phenomena. Almqvist &amp; Wiksell; 1960. 183 р.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Dommisse G. THE Vascular OF Zone THE Surgery CORD* in Spinal. JBJS. 1974;56(2).</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Ahlgren BD, Herkowitz HN. A modified posterolateral approach to the thoracic spine. Journal of spinal disorders. 1995;8(1):69–75.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Lonstein JE, Winter RB, Moe JH, et al. Neurologic deficits secondary to spinal deformity: A review of the literature and report of 43 cases. Spine. 1980;5(4):331–355. doi: 10.1097/00007632-198007000-00007</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Ménard DV. Étude pratique sur le mal de Pott. Paris: Masson; 1900.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Winter RB, Moe JH, Wang JF. Congenital kyphosis: its natural history and treatment as observed in a study of one hundred and thirty patients. JBJS. 1973;55(2):223–274.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Barber JB, Epps CH. Antero-lateral transposition of the spinal cord for paraparesis due to congenital scoliosis. Journal of the National Medical Association. 1968;60(3):169–172.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Cantore GP, Ciappetta P, Costanzo G, Raco A, Salvati M. Neurological deficits secondary to spinal deformities: Their treatment and results in 13 patients. European Neurology. 1989;29(4):181–185. doi: 10.1159/000116407</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Shenouda EF, Nelson IW, Nelson RJ. Anterior transvertebral transposition of the spinal cord for the relief of paraplegia associated with congenital cervicothoracic kyphoscoliosis: Technical note. Journal of Neurosurgery: Spine. 2006;5(4):374–379. doi: 10.3171/spi.2006.5.4.374</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Pennington Z, Ahmed AK, Goodwin CR, Westbroek EM, Sciubba DM. The Use of Sacral Osteotomy in the Correction of Spinal Deformity: Technical Report and Systematic Review of the Literature. World Neurosurgery. 2019;(130):285–292. doi: 10.1016/j.wneu.2019.07.083</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Bourghli A, Abduljawad SM, Boissiere L, Obeid I. Thoracolumbar kyphoscoliotic deformity with neurological impairment secondary to a butterfly vertebra in an adult. Spine Deformity. 2020;8(4):819–827. doi: 10.1007/s43390-020-00050-3</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Delecrin J, et al. Various mechanisms of spinal cord injury during scoliosis surgery. 1994. Р. 13–14.</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Kawahara N, Tomita K, Baba H, et al. Closing-opening wedge osteotomy to correct angular kyphotic deformity by a single posterior approach. Spine. 2001;26(4):391–402. doi: 10.1097/00007632-200102150-00016</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Shimode M, Kojima T, Sowa K. Spinal wedge osteotomy by a single posterior approach for correction of severe and rigid kyphosis or kyphoscoliosis. Spine. 2002;27(20):2260–2267. doi: 10.1097/00007632-200210150-00015</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Shono Y, Abumi K, Kaneda K. One-stage posterior hemivertebra resection and correction using segmental posterior instrumentation. Spine. 2001;26(7):752–757. doi: 10.1097/00007632-200104010-00011</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Kleinberg S, Kaplan A. Scoliosis complicated by paraplegia. JBJS. 1952;34-А(1):162–7.</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>Mironov SP, Vetrile ST, Nacvlishvili ZG, et al. Ocenka osobennostej spinal’nogo krovoobrashcheniya, mikrocirkulyacii v obolochkah spinnogo mozga i nejrovegetativnoj regulyacii pri skolioze. Hirurgiya pozvonochnika. 2006;(3):38–48. (In Russ.). EDN: IBWQQB</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>Ul’rih EV, Mushkin AYu, Rubin AV. Vrozhdennye deformacii pozvonochnikau detej: prognoz epidemiologii i taktika vedeniya. Hirurgiya pozvonochnika. 2009;(2):55–61. (In Russ.). EDN: KTYEZR</mixed-citation></ref><ref id="B27"><label>27.</label><mixed-citation>Senderek J, Bergmann C, Weber S, et al. Mutation of the SBF2 gene, encoding a novel member of the myotubularin family, in Charcot–Marie–Tooth neuropathy type 4B2/11p15. Human molecular genetics. 2003;12(3):349–356. doi: 10.1093/hmg/ddg030</mixed-citation></ref><ref id="B28"><label>28.</label><mixed-citation>Kotani Y, Abumi K, Ito M, Minami A. Improved accuracy of computer-assisted cervical pedicle screw insertion. Journal of neurosurgery. 2003;99(Suppl 3):257–263. doi: 10.3171/spi.2003.99.3.0257</mixed-citation></ref><ref id="B29"><label>29.</label><mixed-citation>Novikov VV, Vasyura AS, Lebedeva MN, Mikhaylovskiy MV, Sadovoy MA. Surgical management of neurologically complicated kyphoscoliosis using transposition of the spinal cord: Case report. International Journal of Surgery Case Reports. 2016;27:13–17. doi: 10.1016/j.ijscr.2016.07.037</mixed-citation></ref><ref id="B30"><label>30.</label><mixed-citation>Saito M. Anterolateral decompression for thoracic myelopathy due to severe kyphosis using the costotransversectomy approach. Rinsho Seikei Geka. 1997;32:523–530.</mixed-citation></ref><ref id="B31"><label>31.</label><mixed-citation>Shah MS, Akbary K, Patel PM, Nene AM. Management of Proximal Thoracic Kyphoscoliosis with Early Myelopathy in a Young Adult with Neurofibromatosis Type 1: A Case Report and Review of Literature. Journal of orthopaedic case reports. 2020;10(4):8–12. doi: 10.13107/jocr.2020.v10.i04.1778</mixed-citation></ref><ref id="B32"><label>32.</label><mixed-citation>Smith JS, Fu KM, Urban P, Shaffrey CI. Neurological symptoms and deficits in adults with scoliosis who present to a surgical clinic: Incidence and association with the choice of operative versus nonoperative management. Journal of Neurosurgery: Spine. 2008;9(4):326–331. doi: 10.3171/SPI.2008.9.10.326</mixed-citation></ref><ref id="B33"><label>33.</label><mixed-citation>Yaman O, Dalbayrak S. Kyphosis and review of the literature. Turkish Neurosurgery. 2014;24(4):455–465.</mixed-citation></ref><ref id="B34"><label>34.</label><mixed-citation>Zhang Z, Wang H, Liu C. Compressive myelopathy in severe angular kyphosis: a series of ten patients. European Spine Journal. 2016;25(6):1897–1903. doi: 10.1007/s00586-015-4051-6</mixed-citation></ref><ref id="B35"><label>35.</label><mixed-citation>Zhang Z, Wang H, Zheng W. Compressive Myelopathy in Congenital Kyphosis of the Upper Thoracic Spine. Clinical Spine Surgery. 2017;30(8):E1098–E1103. doi: 10.1097/BSD.0000000000000350</mixed-citation></ref><ref id="B36"><label>36.</label><mixed-citation>Saifi C, Laratta JL, Petridis P, et al. Vertebral Column Resection for Rigid Spinal Deformity. Global Spine Journal. 2017;7(3):280–290. doi: 10.1177/2192568217699203</mixed-citation></ref><ref id="B37"><label>37.</label><mixed-citation>Auerbach JD, Lenke LG, Bridwell KH, et al. Major complications and comparison between 3-column osteotomy techniques in 105 consecutive spinal deformity procedures. Spine. 2012;37(14):1198–1210. doi: 10.1097/BRS.0b013e31824fffde</mixed-citation></ref><ref id="B38"><label>38.</label><mixed-citation>Lenke LG, Newton PO, Sucato DJ, et al. Complications after 147 consecutive vertebral column resections for severe pediatric spinal deformity: a multicenter analysis. Spine. 2013;38(2):119–132. doi: 10.1097/BRS.0b013e318269fab1</mixed-citation></ref><ref id="B39"><label>39.</label><mixed-citation>Wilcox B, Mobbs RJ, Wu AM, Phan K. Systematic review of 3D printing in spinal surgery: the current state of play. Journal of Spine Surgery. 2017;3(3):433–443. doi: 10.21037/jss.2017.09.01</mixed-citation></ref></ref-list></back></article>
