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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">N.N. Priorov Journal of Traumatology and Orthopedics</journal-id><journal-title-group><journal-title xml:lang="en">N.N. Priorov Journal of Traumatology and Orthopedics</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник травматологии и ортопедии им. Н.Н. Приорова</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0869-8678</issn><issn publication-format="electronic">2658-6738</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">642629</article-id><article-id pub-id-type="doi">10.17816/vto642629</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Clinical case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические случаи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Surgical treatment of double-level spondylolysis of the L4 and L5 vertebrae using custom-made implant</article-title><trans-title-group xml:lang="ru"><trans-title>Оперативное лечение двухуровневого спондилолиза L4 и L5 позвонков с использованием индивидуальной конструкции</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9526-8274</contrib-id><contrib-id contrib-id-type="spin">7052-0220</contrib-id><name-alternatives><name xml:lang="en"><surname>Kuleshov</surname><given-names>Alexander A.</given-names></name><name xml:lang="ru"><surname>Кулешов</surname><given-names>Александр Алексеевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>д-р мед. наук</p></bio><email>cito-spine@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1314-2887</contrib-id><contrib-id contrib-id-type="spin">1402-5186</contrib-id><name-alternatives><name xml:lang="en"><surname>Nazarenko</surname><given-names>Anton G.</given-names></name><name xml:lang="ru"><surname>Назаренко</surname><given-names>Антон Герасимович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), professor of RAS</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор РАН</p></bio><email>NazarenkoAG@cito.priorov.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6689-5220</contrib-id><contrib-id contrib-id-type="spin">9690-5117</contrib-id><name-alternatives><name xml:lang="en"><surname>Vetrile</surname><given-names>Marchel S.</given-names></name><name xml:lang="ru"><surname>Ветрилэ</surname><given-names>Марчел Степанович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>vetrilams@cito-priorov.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0801-0639</contrib-id><contrib-id contrib-id-type="spin">8062-9216</contrib-id><name-alternatives><name xml:lang="en"><surname>Sharov</surname><given-names>Vladislav A.</given-names></name><name xml:lang="ru"><surname>Шаров</surname><given-names>Владислав Андреевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD</p></bio><email>sharov.vlad397@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1553-2782</contrib-id><contrib-id contrib-id-type="spin">2931-0703</contrib-id><name-alternatives><name xml:lang="en"><surname>Zakharin</surname><given-names>Vitaly R.</given-names></name><name xml:lang="ru"><surname>Захарин</surname><given-names>Виталий Романович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>zakhvit@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Priorov National Medical Research Center of Traumatology and Orthopedics</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр травматологии и ортопедии им. Н.Н. Приорова</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2024-12-16" publication-format="electronic"><day>16</day><month>12</month><year>2024</year></pub-date><pub-date date-type="pub" iso-8601-date="2025-02-15" publication-format="electronic"><day>15</day><month>02</month><year>2025</year></pub-date><volume>32</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>173</fpage><lpage>182</lpage><history><date date-type="received" iso-8601-date="2024-12-06"><day>06</day><month>12</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-12-09"><day>09</day><month>12</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Эко-Вектор</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2026-04-08"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0/</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.eco-vector.com/0869-8678/article/view/642629">https://journals.eco-vector.com/0869-8678/article/view/642629</self-uri><abstract xml:lang="en"><p><bold>BACKGROUND:</bold> Spondylolysis is a frequent cause of pain in the lumbar spine in adolescents and young adults, especially those who practice sports. Spondylolysis most commonly occurs at the L5 vertebrae, and less commonly at the L4 vertebrae. Multilevel spondylolysis is extremely rare. The low frequency of occurrence and, as a consequence, difficulties in diagnosing multilevel spondylolysis are the reason for the lack of a unified approach to the treatment of this pathology. In most cases, conservative measures are sufficient, but if they are ineffective, surgical intervention is indicated. Options of surgical treatment are mainly characterised by the focus on restoring the integrity of the arch and, if possible, preserving motion in the vertebral-motor segment. This article describes the experience of using custom-made implants for surgical treatment of double-level spondylolysis and a brief review of the literature.</p> <p><bold>CLINICAL CASE DESCRIPTION:</bold> A clinical case of a 16-year-old patient with bilateral spondylolysis of the L4 and L5 vertebrae is presented. The anamnesis, clinical manifestations, and diagnostic features, including radiological methods of examination, are described. The peculiarities of preoperative planning and modelling of individual implants, surgery and immediate results are presented. A brief literature review describes the main options for surgical treatment of multilevel spondylolysis and demonstrates the validity of the use of individual implants in the surgical treatment of this pathology.</p> <p><bold>CONCLUSION:</bold><bold> </bold>Surgical treatment of double-level bilateral spondylolysis with indirect restoration of the integrity of the vertebral arch with preservation of movements in the vertebral-motor segments can be successfully performed using custom-made implants manufactured using additive technologies. A number of advantages of such implants, such as the ability to design the position and shape of implants considering the individual anatomy of patients, as well as the prevention of contact between the elements of the metal structure during movement, make it possible to improve the results of surgical treatment of double-level spondylolysis.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Введение.</bold><bold> </bold>Спондилолиз является частой причиной возникновения болевого синдрома в поясничном отделе позвоночника у подростков и молодых людей, в особенности занимающихся спортом. Наиболее часто спондилолиз встречается на уровне L5 позвонка, реже — на уровне L4. Многоуровневый спондилолиз является крайне редким явлением. Низкая частота встречаемости и, как следствие, трудности в диагностике многоуровневого спондилолиза являются причиной отсутствия единого подхода к лечению данной патологии. В большинстве случаев достаточно применения консервативных мероприятий, однако при их неэффективности показано проведение оперативного вмешательства. Подходы к оперативному лечению характеризуются главным образом направленностью на восстановление целостности дужки и по возможности сохранение движения в позвоночно-двигательном сегменте. В статье описан опыт применения индивидуальных имплантатов для оперативного лечения двухуровневого спондилолиза и приведён краткий обзор литературы.</p> <p><bold>Описание клинического случая.</bold><bold> </bold>Представлен клинический случай пациента 16 лет с билатеральным спондилолизом L4 и L5 позвонков. Описаны анамнез, клинические проявления, а также особенности диагностики, включая лучевые методы обследования. Представлены особенности предоперационного планирования и моделирования индивидуальных имплантатов, проведения операции и ближайшие результаты. В кратком обзоре литературы описаны основные варианты оперативного лечения многоуровневого спондилолиза и продемонстрирована обоснованность применения индивидуальных имплантатов.</p> <p><bold>Заключение.</bold><bold> </bold>Приведённый в статье клинический случай демонстрирует оперативное лечение двухуровневого билатерального спондилолиза с непрямым восстановлением целостности дужки позвонков с сохранением движений в позвоночно-двигательных сегментах, которое возможно успешно выполнять с использованием персонализированных имплантатов, изготовленных с применением аддитивных технологий. Ряд преимуществ подобных конструкций, таких как возможность проектирования положения и формы имплантатов с учётом индивидуальной анатомии пациентов, а также предотвращения контакта элементов металлоконструкции между собой при движении, позволяет улучшить результаты оперативного лечения двухуровневого спондилолиза.</p></trans-abstract><kwd-group xml:lang="en"><kwd>spondylolysis</kwd><kwd>double-level spondylolysis</kwd><kwd>multilevel spondylolysis</kwd><kwd>direct spondylolysis repair</kwd><kwd>additive technologies</kwd><kwd>personalized implant</kwd><kwd>custom-made implant</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>спондилолиз</kwd><kwd>двухуровневый спондилолиз</kwd><kwd>многоуровневый спондилолиз</kwd><kwd>реконструкция дуги позвонка</kwd><kwd>аддитивные технологии</kwd><kwd>персонализированные имплантаты</kwd><kwd>индивидуальный имплантат</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Wall J, Cook DL, Meehan WP 3rd, Wilson F. 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