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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">N.N. Priorov Journal of Traumatology and Orthopedics</journal-id><journal-title-group><journal-title xml:lang="en">N.N. Priorov Journal of Traumatology and Orthopedics</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник травматологии и ортопедии им. Н.Н. Приорова</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0869-8678</issn><issn publication-format="electronic">2658-6738</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">677132</article-id><article-id pub-id-type="doi">10.17816/vto677132</article-id><article-id pub-id-type="edn">ASPFNF</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Clinical case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические случаи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Surgical treatment of patients with atypical femoral fractures of various etiologies: case reports</article-title><trans-title-group xml:lang="ru"><trans-title>Оперативное лечение пациентов с атипичными переломами бедренной кости различного генеза: клинические случаи</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-9679-5673</contrib-id><contrib-id contrib-id-type="spin">5519-5510</contrib-id><name-alternatives><name xml:lang="en"><surname>Shevyrev</surname><given-names>Konstantin V.</given-names></name><name xml:lang="ru"><surname>Шевырев</surname><given-names>Константин Васильевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine), Associate Professor</p></bio><bio xml:lang="ru"><p>канд. мед. наук, доцент</p></bio><email>skv-moniki@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-0069-0155</contrib-id><contrib-id contrib-id-type="spin">2022-3822</contrib-id><name-alternatives><name xml:lang="en"><surname>Shavyrin</surname><given-names>Dmitriy A.</given-names></name><name xml:lang="ru"><surname>Шавырин</surname><given-names>Дмитрий Александрович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>д-р мед. наук</p></bio><email>Shavyrin@inbox.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-5033-4379</contrib-id><contrib-id contrib-id-type="spin">8639-8192</contrib-id><name-alternatives><name xml:lang="en"><surname>Martynenko</surname><given-names>Dmitry V.</given-names></name><name xml:lang="ru"><surname>Мартыненко</surname><given-names>Дмитрий Владимирович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine), Associate Professor</p></bio><bio xml:lang="ru"><p>канд. мед. наук, доцент</p></bio><email>Orthomoniki@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2304-8483</contrib-id><contrib-id contrib-id-type="spin">8015-7004</contrib-id><name-alternatives><name xml:lang="en"><surname>Voloshin</surname><given-names>Victor P.</given-names></name><name xml:lang="ru"><surname>Волошин</surname><given-names>Виктор Парфентьевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор</p></bio><email>victor_voloshin@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-8229-6399</contrib-id><contrib-id contrib-id-type="spin">6517-2669</contrib-id><name-alternatives><name xml:lang="en"><surname>Kondaleva</surname><given-names>Regina V.</given-names></name><name xml:lang="ru"><surname>Кондалева</surname><given-names>Регина Владимировна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>regina.kondaleva@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-8452-6546</contrib-id><contrib-id contrib-id-type="spin">6341-8342</contrib-id><name-alternatives><name xml:lang="en"><surname>Shakhova</surname><given-names>Margarita A.</given-names></name><name xml:lang="ru"><surname>Шахова</surname><given-names>Маргарита Алексеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>margaritasha07@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Moscow Regional Clinical Research Institute named after M.F. Vladimirsky</institution></aff><aff><institution xml:lang="ru">Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2025-12-21" publication-format="electronic"><day>21</day><month>12</month><year>2025</year></pub-date><pub-date date-type="pub" iso-8601-date="2026-04-02" publication-format="electronic"><day>02</day><month>04</month><year>2026</year></pub-date><volume>33</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>144</fpage><lpage>160</lpage><history><date date-type="received" iso-8601-date="2025-03-13"><day>13</day><month>03</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-08-01"><day>01</day><month>08</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2026, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2026, Эко-Вектор</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2027-04-02"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.eco-vector.com/0869-8678/article/view/677132">https://journals.eco-vector.com/0869-8678/article/view/677132</self-uri><abstract xml:lang="en"><p><bold>BACKGROUND: </bold>Atypical femoral fractures are rare stress or fatigue fractures that occur between the subtrochanteric and supracondylar regions and initially involve the lateral cortex of the femur, developing over time, most often after prolonged suppression of bone remodeling with anti-osteoporotic medications. To date, such fractures have been associated with bisphosphonates, corticosteroids, denosumab, romosozumab, proton pump inhibitors, autoimmune diseases, Asian ethnicity, and varus deformity of the femur and knee. Contemporary scientific data discusses issues of conservative management and prophylactic osteosynthesis in incomplete atypical femoral fractures, as well as methods of osteosynthesis for complete fractures. Most authors support the need for prophylactic osteosynthesis for incomplete fractures and intramedullary locked osteosynthesis for complete atypical femoral fractures.</p> <p><bold>CLINICAL Case description:</bold> The article presents three clinical cases. The first demonstrates treatment approaches in an older patient with atypical femoral fractures associated with long-term bisphosphonate use. One femur with a complete atypical fracture achieved union after revision surgery, whereas the contralateral femur required revision intervention after intramedullary locked osteosynthesis. The second case presents the results of surgical treatment in a young patient with complete and incomplete fractures associated with varus deformity of the femurs. On one side, the femur with a complete fracture achieved union after repeated revision surgeries with correction of deformity; the other femur with an incomplete fracture achieved union with conservative management. The third clinical case demonstrates the treatment results of a middle-aged patient with bilateral atypical femoral fractures of unknown etiology. The complete femoral fracture achieved union after osteosynthesis with two plates, whereas the contralateral femur with an incomplete fracture united after application of a lateral compression plate.</p> <p><bold>CONCLUSION: </bold>The approaches and treatment outcomes presented in this article are partially consistent with published data and allow formulation of treatment strategies for atypical femoral fractures. Incomplete atypical femoral fractures can be successfully treated with osteosynthesis using a single lateral plate applied in a compression mode or with intramedullary locked osteosynthesis. Complete and nonunited atypical fractures should be rigidly stabilized, for example, with two plates. Bone grafting may increase the likelihood of union in complete fractures and in nonunions following such fractures.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование. </bold>Атипичные переломы бедренной кости — это редкие стрессовые или усталостные переломы, которые возникают между подвертельной и надмыщелковой зонами и изначально затрагивают латеральную стенку бедренной кости, развиваясь со временем, чаще всего после длительного подавления ремоделирования костной ткани с помощью препаратов для лечения остеопороза. На сегодняшний день установлена связь развития таких переломов с приёмом бисфосфонатов, кортикостероидов, препаратов деносумаб и ромосозумаб, ингибиторов ионной помпы, с наличием аутоиммунных заболеваний, принадлежностью к азиатской расе и варусной деформацией бедра и колена. В современной литературе обсуждаются вопросы консервативного лечения и профилактического остеосинтеза при незавершённых атипичных переломах бедренной кости и способов остеосинтеза при завершённых переломах. Большинство авторов склоняются к необходимости профилактического остеосинтеза при незавершённых переломах и внутрикостного блокируемого остеосинтеза при завершённых атипичных переломах бедренной кости.</p> <p><bold>Описание клинических случаев. </bold>В статье показаны три клинических случая. Первый демонстрирует подходы к лечению пожилой пациентки с атипичными переломами бедренных костей на фоне длительного приёма бисфосфонатов. Одна бедренная кость с завершённым атипичным переломом консолидирована после ревизионной операции, контралатеральное бедро после внутрикостного блокируемого остеосинтеза потребовало ревизионного вмешательства. Второй случай представляет результаты оперативного лечения молодой пациентки с завершённым и незавершённым переломами на фоне варусной деформации бедренных костей. С одной стороны бедренная кость с завершённым переломом консолидирована после повторных ревизионных операций с устранением деформации, второе бедро с незавершённым переломом консолидировано на фоне консервативного лечения. И третий клинический случай демонстрирует результаты лечения пациентки среднего возраста с билатеральными атипичными переломами бедренных костей неустановленного генеза. Завершённый перелом бедренной кости консолидирован после остеосинтеза двумя пластинами, контралатеральное бедро с незавершённым переломом срослось после наложения латеральной компрессирующей пластины.</p> <p><bold>Заключение. </bold>Представленные нами в статье подходы и результаты лечения пациенток частично совпадают с литературными данными и позволяют сформулировать подходы к лечению атипичных переломов бедренной кости. Незавершённые атипичные переломы бедренной кости могут быть успешно пролечены остеосинтезом одной латеральной пластиной, наложенной в компрессирующем режиме, или внутрикостным блокируемым остеосинтезом. Завершённые и несросшиеся атипичные переломы целесообразно ригидно фиксировать, например двумя пластинами. Костная пластика может повысить вероятность сращения при завершённых переломах и несращениях после них.</p></trans-abstract><kwd-group xml:lang="en"><kwd>atypical femoral fracture</kwd><kwd>osteosynthesis</kwd><kwd>case report</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>атипичный перелом бедренной кости</kwd><kwd>остеосинтез</kwd><kwd>клинический случай</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Shane E, Burr D, Abrahamsen B, et al. Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American Society for Bone and Mineral Research. 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