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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">N.N. Priorov Journal of Traumatology and Orthopedics</journal-id><journal-title-group><journal-title xml:lang="en">N.N. Priorov Journal of Traumatology and Orthopedics</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник травматологии и ортопедии им. Н.Н. Приорова</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0869-8678</issn><issn publication-format="electronic">2658-6738</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">90775</article-id><article-id pub-id-type="doi">10.17816/vto90775</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original study articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Characteristics of the psoas minor muscle in modeling lateral interbody spondylodesis of the lumbar spine</article-title><trans-title-group xml:lang="ru"><trans-title>Характеристика малой поясничной мышцы при моделировании бокового межтелового спондилодеза поясничного отдела позвоночника</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8929-8784</contrib-id><contrib-id contrib-id-type="scopus">57196004532</contrib-id><contrib-id contrib-id-type="spin">3007-1309</contrib-id><name-alternatives><name xml:lang="en"><surname>Filimonova</surname><given-names>Galina N.</given-names></name><name xml:lang="ru"><surname>Филимонова</surname><given-names>Галина Николаевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Biol.), senior researcher</p></bio><bio xml:lang="ru"><p>канд. биол. наук, старший научный сотрудник</p></bio><email>galnik.kurgan@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9974-2204</contrib-id><contrib-id contrib-id-type="spin">8301-1475</contrib-id><name-alternatives><name xml:lang="en"><surname>Diuriagina</surname><given-names>Olga V.</given-names></name><name xml:lang="ru"><surname>Дюрягина</surname><given-names>Ольга Владимировна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Vet.), head of the experimental laboratory</p></bio><bio xml:lang="ru"><p>канд. вет. наук, заведующая экспериментальной лабораторией</p></bio><email>diuriagina@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8627-2749</contrib-id><contrib-id contrib-id-type="scopus">55207639900</contrib-id><contrib-id contrib-id-type="spin">3754-7508</contrib-id><name-alternatives><name xml:lang="en"><surname>Antonov</surname><given-names>Nikolai I.</given-names></name><name xml:lang="ru"><surname>Антонов</surname><given-names>Николай Иванович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Biol.), researcher</p></bio><bio xml:lang="ru"><p>канд. биол. наук, научный сотрудник</p></bio><email>aniv-niko@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8293-0521</contrib-id><contrib-id contrib-id-type="scopus">54941390600</contrib-id><contrib-id contrib-id-type="spin">6382-1107</contrib-id><name-alternatives><name xml:lang="en"><surname>Ryabykh</surname><given-names>Sergei O.</given-names></name><name xml:lang="ru"><surname>Рябых</surname><given-names>Cергей Олегович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), traumatologist-ortopedist, pediatric and spinal surgeon</p></bio><bio xml:lang="ru"><p>д-р мед. наук, врач — травматолог-ортопед, детский и спинальный хирург</p></bio><email>ryabykhco@cito-priorov.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Russian Ilisarov Medical Research Center for Traumatology and Orthopedics</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр травматологии и ортопедии им. академика Г.А. Илизарова</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">N.N. Priorov Russian Scientific Research Institute of Traumatology and Orthopedics</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр травматологии и ортопедии им. академика Н.Н. Приорова</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2022-07-01" publication-format="electronic"><day>01</day><month>07</month><year>2022</year></pub-date><pub-date date-type="pub" iso-8601-date="2022-03-15" publication-format="electronic"><day>15</day><month>03</month><year>2022</year></pub-date><volume>29</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>47</fpage><lpage>56</lpage><history><date date-type="received" iso-8601-date="2022-02-08"><day>08</day><month>02</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-04-21"><day>21</day><month>04</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, ООО "Эко-Вектор"</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2023-10-04"/></permissions><self-uri xlink:href="https://journals.eco-vector.com/0869-8678/article/view/90775">https://journals.eco-vector.com/0869-8678/article/view/90775</self-uri><abstract xml:lang="en"><p><bold><italic>В</italic></bold><italic><bold>ACKGROUND:</bold> </italic>For the treatment of degenerative diseases of the spine, various deformities, a minimally invasive technique of lateral lumbar interbody fusion is used, which minimizes the risks of spinal cord injury. In the development of these pathologies, the most important role is assigned to the paraspinal muscles, the histological features of which are insufficiently elucidated in the relevant literature when modeling spondylodesis.</p> <p><bold><italic>А</italic></bold><italic><bold>IM:</bold> </italic>To investigate the effect of lateral interbody vertebral fusion (spondylodesis) when introducing titanium implants on the histostructure of the psoas minor muscle.</p> <p><bold><italic>М</italic><italic>ATERIALS AND METHODS: </italic></bold>Experiments were performed in 14 mongrel dogs, 3 individuals — the control group (norm). The аnimals underwent discectomy at the level of L4–5, L5–6 vertebrae through the lateral approach on the right, and interbody titanium implants were installed. The lumbar spine was stabilized with an external fixator for 30 days. Paraffin muscle sections were stained with hematoxylin-eosin, according to Masson.</p> <p><italic><bold>RESULTS:</bold> </italic>During the experiment, an increased variety of myosymplast diameters, loss of polygonality of their profiles, fibrosis of the interstitial space, and sclerotization of the vascular membranes were observed in the psoas minor muscle. The volume density of endomysium in both muscles increased 1.5 times relative to the norm after 6 months Other parameters decreased: the volume of myosymplasts was 95%, that of microvessels — 73% on the left, 83% on the right. On the other hand, the degree of fatty infiltration increased, amounting to 276% on the left and 394% — on the right of the normal parameters. After 18 months, the bulk density of muscle fibers on the left was restored to the value in the control, on the right it was only 95%. The degree of sclerotization in the muscle on the left is 133%, on the right — 161% of the norm; the index of fatty infiltration was 146% on the left and 339% on the right of the normal parameter.</p> <p><bold><italic>CONCLUSION: </italic></bold>pathohistological changes in the psoas minor during lateral interbody fusion are more pronounced on the side of the operative approach, which necessitates minimizing trauma to the paravertebral muscles during operations in order to prevent sclerotization and fatty involution of muscle tissue.</p></abstract><trans-abstract xml:lang="ru"><p><bold><italic>Обоснование.</italic></bold> Для лечения дегенеративных заболеваний позвоночника, различных деформаций применяется малоинвазивная методика бокового поясничного межтелового спондилодеза, при которой минимальны риски повреждения спинного мозга. В развитии данных патологий важнейшая роль отведена параспинальным мышцам, гистологические особенности которых при моделировании спондилодеза в релевантной литературе освещены недостаточно.</p> <p><bold><italic>Цель.</italic></bold> Исследовать влияние техники бокового межтелового спондилодеза с внедрением титановых имплантатов на гистоструктуру малой поясничной мышцы.</p> <p><bold><italic>Материалы и методы.</italic> </bold>Проведены эксперименты на 14 беспородных собаках, 3 интактных особи составили контрольную группу (норма). Животным через боковой доступ справа выполняли дискэктомию на уровне позвонков L4–5, L5–6, устанавливали межтеловые титановые имплантаты. Поясничный отдел стабилизировали аппаратом внешней фиксации в течение 30 сут. Парафиновые срезы мышцы окрашивали гематоксилином-эозином, по Массону.</p> <p><bold><italic>Результаты. </italic></bold>В ходе эксперимента в малой поясничной мышце наблюдалось повышенное разнообразие диаметров миосимпластов, утрата полигональности их профилей, фиброзирование интерстициального пространства, склеротизация оболочек сосудов. Через 6 мес в 1,5 раза возрастала объемная плотность эндомизия. Другие параметры уменьшались: относительный объем миосимпластов составил 95% в обеих мышцах от параметра в норме, объем микрососудов — 73% слева и 83% справа. Степень жировой инфильтрации слева — 276%, справа — 394% от параметра в норме. Через 18 мес объемная плотность мышечных волокон слева восстанавливалась до значения в норме, справа составила лишь 95%. Степень склеротизации в мышце слева — 133%, справа — 161%; индекс жировой инфильтрации слева — 146%, справа — 339% от параметров в норме.</p> <p><bold><italic>Вывод.</italic> </bold>Патогистологические изменения малой поясничной мышцы при боковом межтеловом спондилодезе выражены значительнее со стороны оперативного доступа, что обуславливает необходимость минимизировать травматизацию паравертебральных мышц во время операций с целью предотвратить склеротизацию и жировую инволюцию мышечной ткани.</p></trans-abstract><kwd-group xml:lang="en"><kwd>lateral interbody vertebral fusion (spondylodesis)</kwd><kwd>experiment</kwd><kwd>psoas minor muscle</kwd><kwd>sclerotization</kwd><kwd>fatty involution</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>боковой межтеловой спондилодез</kwd><kwd>эксперимент</kwd><kwd>малая поясничная мышца</kwd><kwd>склеротизация</kwd><kwd>жировая инволюция</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Liang C, Sun J, Cui X, et al. 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