Anterior mini-invasive approach to the spine that enables to achieve all levels from T12 to SI is described. This approach can be used both in injuries and in degenerative pathology of the spine. Surgical results were studied roentgenologically and that gave us the possibility to assess the performed osteosynthesis and the equilibrium in the sagittal plane. The suggested approach is the continuation of classical anterior approaches and it provides significant advantages for the performance of various surgical interventions at all levels of the lumbar spine without damaging the muscles. Theoretically it possesses neither neurologic risk nor the problem of blood loss which occur when intervertebral transplantation is performed via the posterior approach. Anterior extraperitoneal mini-approach enables to adjust the size of the graft and to perform the correction of sizable deformities using either rigid or semirigid graft. It can also be the only choice in case of considerable loss of posterior bone mass, weakness of the posterior graft and infection in the zone of the posterior approach.