Arguments and Facts of Thrombosis Prophylaxis in Surgical Traumatology and Orthopaedics



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Abstract

Modern data on the rate of venous thromboembolism development after orthopaedic surgeries as well as the results of international prospective ETHOS study (17 countries including Russia, 161 centers) are presented. The aim of the study was to assess post-operative venous thromboembolism prophylaxis prescribed and received in patients after high-risk orthopaedic surgeries (total hip arthroplasty, femur osteosynthesis, total knee arthroplasty) as compared with the 2004 American College of Chest Physicians (ACCP) guidelines. Peculiarities of thrombosis prophylaxis in Russia centers are shown.

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Аргументы и факты медикаментозной тромбопрофилактики в оперативной травматологии и ортопедии
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About the authors

A. F Lazarev

Email: lazarev.anatoly@gmail.com

References

  1. Cohen A.T. Presented at the 5th Annual Congress of the European Federation of Internal Medicine, 2005.
  2. Lindblad B., Eriksson A., Bergquist D. Autopsy-verified pulmonary embolism in a surgical department: analysis of the period from 1951 to 1968. Br. J. Surg. 1991; 78 (7): 849-52.
  3. Sandler D.A., Martin J.F. Autopsy proven pulmonary embolism in hospital patients: are we detecting enough deep vein thrombosis? J. R. Soc. Med. 1989; 82 (4): 203-5.
  4. Stein P.D., Henry J.W. Prevalence of acute pulmonary embolism among patients in a general hospital and at autopsy. Chest. 1995; 108 (4): 978-81.
  5. Schellong S.M., Bounameaux H., Buller H. Venous thromboembolism. In: Camm A.J., Luscher Th.F., Serruys P. W., eds. The ESC Textbook of Cardiovascular Medicine. Blackwell Publishing; 2006: 1067-92.
  6. Agnelli G. Prevention of venous thromboembolism in surgical patients. Circulation. 2004; 110: IV-4 - IV-12.
  7. Anderson F.A., Wheeler H.B., Goldberg R.J. Goldberg R.J., Hosmer D.W., Patwardhan N.A., Jovanovic B., Forcier A., Dalen J.E. A population-based perspective of hospital incidence and case-fatality rates of deep venous thrombosis and pulmonary embolism: the Worcester DVT study. Arch. Intern. Med. 1991; 151 (5): 933-8.
  8. Geerts W.H., Heit J.A., Clagett G.P. Pineo G.F., Colwell CW., Anderson F.A. Jr., Wheeler H.B. Prevention of venous thromboembolism. Chest. 2001; 119 (1 Suppl): 132S-175S.
  9. Профилактика венозных тромбоэмболических осложнений в травматологии и ортопедии. Российские клинические рекомендации. Травматология и ортопедия России. 2012; 1 (63, Приложение) [Prevention of thromboembolic complications in traumatology and orthopaedics. Travmatologiya i ortopediya Rossii. 2012; 1 (63, Appendix) (in Russian)].
  10. Cipolle M.D., Wojcik R., Seislove E., Wasser T.E., Pasquale M.D. The role of surveillance duplex scanning in preventing venous thromboembolism in trauma patients. J. Trauma. 2002; 52 (3): 453-62.
  11. Paiement G.D., Wessinger S. J., Harris W. H. Cost-effectiveness of prophylaxis in total hip replacement. Am. J. Surg. 1991; 161 (4): 519-24.
  12. Douketis J.D., Eikelboom J.W., Quinlan D.J., Willan A.R., Crowther M.A. Short-duration porophylaxis against venous thromboembolism after total hip and knee replacement: a meta-analysis of prospective studies investigating symptomatic outcomes. Arch. Intern. Med. 2002; 162 (13): 1465-71.
  13. Eriksson B.I., Lassen M.R. The PENTassccharide in Hip- FRActure Surgery Plus (PENTIFRA Plus) Investigators. Duration of prophylaxis against venous thromboembolism with fondaparinux after hip fracture surgery: a multicenter, randomized, placebo-controlled double-blind study. Arch. Intern. Med. 2003; 163 (11): 1337-42.
  14. Prevention of fatal postoperative pulmonary embolism by low doses of heparin. An international multicentre trial. Lancet. 1975; 2 (7924): 45-51.
  15. White R.H., Romano P.S., Zhou H., Rodrigo J., Bargar W. Incidence and time course of thromboembolic outcomes following total hip or knee arthroplasty. Arch. Intern. Med. 1998; 158 (14): 1525-31.
  16. Clagett G.P., Reisch J.S. Prevention of venous thromboembolism in general surgical patients: results of metaanalysis. Ann. Surg. 1988; 208 (2): 227-40.
  17. Collins R., Scrimgeour A., Yusuf S., Peto R. Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin: overview of randomized trials in general, orthopedic, and urologic surgery. N. Engl. J. Med., 1988; 318 (18): 1162-73.
  18. Koch A., Ziegler S., Breitschwerdt H., Victor N. Low molecular weight heparin and unfractionated heparin in thrombosis prophylaxis: meta-analysis based on original patient data. Thromb. Res. 2001; 102 (4): 295-309.
  19. Guijarro R., Montes J., San Romön C, Arcelus JI, Barillari G., Granero X., Monreal M.Venous thromboembolism and bleeding after total knee and hip arthroplasty. Findings from the Spanish National Discharge Database. Thromb. Haemost. 2011; 105 (4): 610-5.
  20. Geerts W.H., Bergqvist D., Pineo G.F., Heit J.A., Samama C.M., Lassen M.R., Colwell CW. Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008; 133 (6 Suppl): 381S-453S.
  21. Geerts W.H., Pineo G.F., Heit J.A., Bergqvist D., Lassen M.R., Colwell CW, Ray J.G. Prevention of venous thromboembolism: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004; 126 (3 Suppl): 338S-400S.
  22. Cardiovascular Disease Educational and Research Trust; Cyprus Cardiovascular Disease Educational and Research Trust; European Venous Forum et al. Prevention and treatment of venous thromboembolism. International Consensus Statement (guidelines according to scientific evidence). Int. Angiol. 2006; 25 (2): 101-61.
  23. Warwick D., Friedman R.J., Agnelli G. Gil-Garay E., Johnson K., FitzGerald G., Turibio F.M. Insufficient duration of venous thromboembolism prophylaxis after total hip or knee replacement when compared with the time course of thromboembolic events: findings from the Global Orthopaedic Registry. J. Bone Joint Surg. Br. 2007; 89 (6): 799-807.
  24. Tapson V.F., Hyers T.M., Waldo A.L., Ballard D.J., Becker R.C., Caprini J.A., Khetan R., Wittkowsky A.K., Colgan K.J., Shillington A.C. Antithrombotic therapy practices in US hospitals in an era of practice guidelines. Arch. Intern. Med. 2005; 165 (13): 1458-64.
  25. Cohen A.T., Tapson V.F., Bergmann J.F., Goldhaber S.Z., Kakkar A.K., Deslandes B., Huang W., Zayaruzny M., Emery L., Anderson F.A. Jr. Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): a multinational cross-sectional study. Lancet 2008; 371 (9610): 387-94.
  26. Friedman R.J., Gallus A.S., Cushner F.D., Fitzgerald G., Anderson F.A. Jr. Physician compliance with guidelines for deep-vein thrombosis prevention in total hip and knee arthroplasty. Curr. Med. Res. Opin. 2008; 24 (1): 87-7.
  27. Bergqvist D., Lindblad B. A 30-year survey of pulmonary embolism verified at autopsy: an analysis of 1274 surgical patients. Br. J. Surg. 1985; 72 (2): 105-8.
  28. Bergqvist D. The post discharge risk of venous thromboembolism after hip replacement. The role of prolonged prophylaxis. Drugs. 1996; 52 (Suppl 7): 55-9.
  29. Bergqvist D., Agnelli G., Cohen A.T., Eldor A., Nilsson P.E., Le Moigne-Amrani A., Dietrich-Neto F. Duration of prophylaxis against venous thromboembolism with enoxaparin after surgery for cancer. N. Engl. J. Med. 2002; 346 (13): 975-980.
  30. Bergqvist D., Benoni G., Bj^gell O., Fredin H., Hedlundh U., Nicolas S., Nilsson P., Nylander G. Low-molecular-weight heparin (enoxaparin) as prophylaxis against venous thromboembolism after total hip replacement. N. Engl. J. Med. 1996; 335 (10): 696-700.
  31. Planes A., Vochelle N., Darmon J.Y., Fagola M., Bellaud M., Huet Y. Risk of deep-venous thrombosis after hospital discharge in patients having undergone total hip replacement: double-blind randomized comparison of enoxaparin versus placebo. Lancet. 1996; 348 (9022): 224-8.
  32. Hull R.D., Pineo G.F., Stein P.D., Mah A.F., MacIsaac S.M., Dahl O.E., Butcher M., Brant R.F., Ghali W.A., Bergqvist D., Raskob G.E. Extended out-of-hospital low-molecular- weight heparin prophylaxis against deep venous thrombosis in patients after elective hip arthroplasty: a systematic review. Ann. Intern. Med. 2001; 135 (10): 858-69.
  33. Friedman R.J. Extended thromboprophylaxis after hip or knee replacement. Orthopedics 2003; 26 (2 Suppl): S225-S230.
  34. Eikelboom J.W., Mazzarol A., Quinlan D.J., Beaver R., Williamson J., Yi Q., Hankey G.J. Thromboprophylaxis practice patterns in two Western Australian teaching hospitals. Haematologica 2004; 89 (5): 586-93.
  35. Bikdeli B., Sharif-Kashani B., Raeissi S., Ehteshami- Afshar S., Behzadnia N., Masjedi M.R. Chest physicians’ knowledge of appropriate thromboprophylaxis: insights from the PROMOTE study. Blood Coagul Fibrinolysis. 2011; 22 (8): 667-72.
  36. Weigelt J.A., Lal A., Riska R. Venous thromboembolism prophylaxis in surgical patients: identifying a patient group to maximize performance improvement. Jt Comm. J. Qual. Patient Saf. 2011; 37 (4): 178-83.
  37. Schleyer A.M., Schreuder A.B., Jarman K.M., Logerfo J.P., Goss J.R. Adherence to guideline-directed venous thromboembolism prophylaxis among medical and surgical inpatients at 33 academic medical centers in the United States. Am. J. Med. Qual. 2011; 26 (3): 174-80.
  38. Amin A.N., Stemkowski S., Lin J., Yang G. Preventing venous thromboembolism in US hospitals: are surgical patients receiving appropriate prophylaxis? Thromb. Haemost. 2008; 99 (4): 796-7.
  39. Borah B., McDonald H., Henk J. et al. Alignment to ACCP prophylaxis guidelines and VTE outcomes in THR and TKR patients [abstract]. Blood 2008; 112: Abstract 170.
  40. Bergqvist D, Arcelus J.I., Felicissimo P.; ETHOS investigators. Evaluation of the duration of thromboembolic prophylaxis after high-risk orthopaedic surgery: the ETHOS observational study. Thromb. Haemost. 2012; 107 (2): 270-9.
  41. American Academy of Orthopaedic Surgeons clinical guideline on prevention of pulmonary embolism in patients undergoing total hip or knee arthroplasty, May 2007. http://www.aaos.org/Research/guidelines/ PE_guideline.pdf.
  42. Eikelboom J., Karthikeyan G., Fagel N., Hirsh J. American Association of Orthopedic Surgeons and American College of Chest Physicians guidelines for venous thromboembolism prevention in hip and knee arthroplasty differ: what are the implications for clinicians and patients? Chest. 2009; 135 (2): 513-20.

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