Neurology BulletinNeurology Bulletin1027-48982304-3067Eco-Vector1369210.17816/nb13692WERNICKE'S ENCEPHALOPATHY IN PREGNANT WOMEN WITH TOXICOSIS AND CONTINUED VOMITING: OUR OWN OBSERVATION AND ANALYSIS OF CLINICAL CASESMendelevichЕlena Gкафедра неврологии и реабилитации; Казанский государственный медицинский университет; Каzan state medical universityemendel@mail.ruBogdanovEnver Iкафедра неврологии и реабилитации; Казанский государственный медицинский университет; Каzan state medical university-KhusainovaLeisan Vкафедра неврологии и реабилитации; Казанский государственный медицинский университет; Каzan state medical university-Каzan state medical university15032011XLIII110410620062019Copyright © 2011, Mendelevich Е.G., Bogdanov E.I., Khusainova L.V.2011There was described a clinical observation of 29 year old woman with Wernicke's encephalopathy. This rare complication of pregnancy was caused by thiamine deficiency due to severe vomiting.Wernicke's encephalopathycontinued vomiting of pregnantthiamine deficiencyэнцефалопатия Верникеупорная рвота беременныхдефицит тиамина[1. Дамулин, И.В. Неврологические расстройства при алкоголизме / И.В. Дамулин, Т.Е. Шмидт // Неврол. журн. - 2004. - Т.9, №2. - С. 4-10.][2. Дамулин, И.В Когнитивные расстройства при алкоголизме //Русск. Мед. журнал. - 2005. - Т. 13, № 12. - С. 785-789.][3. Chiossi, G. Hyperemesis gravidarum complicated by Wernicke encephalopathy: background, case report, and review of the literature / G. Chiossi, I. Neri, M. Cavazzuti et al. // J. Obstet Gynecol Surv. - 2006. - Vol. 61(4). - P. 255-268.][4. Ebouй, C. A rare complication of vomiting in pregnancy: Wernicke's encephalopathy / C. Ebouй, C. Carlier-Guйrin, V. de La Sayette et al.// J. Gynecol Obstet Biol Reprod (Paris). - 2006. - Vol. 35. - S8. - P. 822-825.][5. McIntosh, C. Alcohol and the nervous system / C. McIntosh, J. Chick //J. Neurol. Neurosurg. Psychiatry. - 2004. - Vol.75 (Suppl.3). - P. 16-21.][6. Phayphet, M. Hyperemesis gravidarum: a rare cause of Wernicke encephalopathy / M. Phayphet, C. Rafat, F. Andreux et. al. // Presse Med. - 2007. - Vol. 36. - S.12. - P. 1759-1761. Epub 2007.][7. Rabenda-Јacka, K. Wernicke's encephalopathy due to hyperemesis gravidarum / K. Rabenda-Јacka, J. Wilczyсski, G. Breborowicz et al. // J. Ginekol Pol-. 2003. - Vol. 74. - S.8. - P. 633-637.][8. Tan, J. Wernicke's Encephalopathy in Patients with Hyperemesis Gravidarum / J. Tan, K. Ho // Singapore Med. J. - 2001. - Vol. 42. - S.3. - P. 124-125.][9. Togay-Isikay, C. Wernicke's encephalopathy due to hyperemesis gravidarum: an under-recognized condition / C. Togay-Isikay, A. Yiрit, N. Mutluer // Aust NZJ Obstet Gynaecol. - 2001. - Vol. 41. - P. 453-456.][10. Warach, S. Imaging the brain lesions of alcoholics / S. Warach, M. Charness / In: Greenberg J., ed., Neuroimaging (International edition). - McGraw-Hill, Inc., 1995. - P. 503-515.][11. Watanabe, K. Wernicke's encephalopathy in early pregnancy complicated by disseminated intravascular coagulation / K. Watanabe, K. Tanaka, J. Masuda // Virchows Arch. - 1983. - Vol. 400. - P. 213-218.][12. Williams, N. Wernicke's Encephalopathy Complicating Pregnancy in a Woman with Neonatal Necrotizing Enterocolitis and Resultant Chronic Malabsorption / N. Williams, S. Wiegand, D. McKenna // Am. J. Perinatol. - 2009. - Vol. 26. - S.7. - P. 519-521.][13. Wilson R., Kuncl R., Corse A. Wernicke's encephalopathy: beyond alcoholism www.nature.com/clinicalpractice/neuro January 2006 Vol. 2, № 1.]