Neurology BulletinNeurology Bulletin1027-48982304-3067Eco-Vector1398510.17816/nb13985Research ArticlePROGNOSIS OF CLINICAL OUTCOMES IN THE LONG TERM PERIOD AFTER CAROTID ENDARTERECTOMYAkhmadeevaLeila RDepartment of Neurology, Neurosurgery and medical genetics-BikbulatovaLarisa F1) Department of Neurology, Neurosurgery and medical genetics; 2) neurological department for patients with strokelarisaflurovna@list.ruIshbuldinaGylnara Ineurological department for patients with stroke-PlechevVladimir VDepartment of Surgery-AkhmadullinFlarit FDepartment of Ore Mining Industry and Subsoil Protection-VeytsmanBoris ADepartment of System Biology and Center for Computational Materials Science-Bashkortostan State Medical University1) Bashkortostan State Medical University2) Clinical Hospital № 18 of Ufa cityClinical Hospital № 18 of Ufa cityInterbranch InstituteGeorge Mason University (Fairfax, Virginia, USA)15092016XLVIII351020062019Copyright © 2016, Akhmadeeva L.R., Bikbulatova L.F., Ishbuldina G.I., Plechev V.V., Akhmadullin F.F., Veytsman B.A.2016In this article we describe the factors that can influence the occurrence of stroke in long term period in patients after reconstructive surgery on the carotid arteries. We observed 195 patients (mean age 63,6 ± 8,4 years) who underwent reconstructive surgery on the carotid arteries for the stenotic lesions. We made a clinical examination of patients, which included clinical interview, objective examination (somatic and neurological), neuropsychological and laboratory and instrumental tests. As the result of our study, we obtained data about the most important factors influencing the incidence of strokes after this type of surgery. For the first time we presented the data confirming that if carotid endarterectomy is performed earlier, it significantly (p=0.004) decreases the incidence of strokes after these surgeriesatherosclerosis of the carotid arteriescarotid endarterectomyischemic strokecarotid restenosisатеросклероз каротидных артерийкаротидная эндартерэктомияишемический инсульткаротидный рестеноз[Ахмадеева Л.Р., Вейцман Б.А., Харисова Э.М., Гуров Д.П., Фатыхова М.Р. Использование данных стабилометрии для прогнозирования падений у пожилых пациентов неврологического стационара // Уральский медицинский журнал. 2013. № 1 (106). С. 47-50.][Гусев Е.И, Скворцова Л.В., Стаховская Л.В. и др. Эпидемиология инсульта в России // Consilium medicum. 2011, спецвыпуск. С. 5-7.][Покровский А.В., Белоярцев Д.Ф., Адырхаев З.А. и др. Влияет ли способ каротидной реконструкции на непосредственные результаты вмешательства? // Ангиология и сосудистая хирургия. 2012. Т.18, № 3. С. 81-91.][Покровский А.В., Гонтаренко В.Н. Состояние сосудистой хирургии в России в 2012 году [Электронный ресурс] // Российское общество ангиологов и сосудистых хирургов. М., 2013. Режим доступа: http://angiolsurgery.org/society/report/2012/index.pdf][Campbell C., Smyth S., Montalescot G., Steinhubl S. Aspirin dose for the prevention of cardiovascular disease: A systematic review // JAMA. 2007. Vol. 297. P. 2018-2024.][Hothorn T., Hornik K., Zeileis A. Unbiased recursive partitioning: A conditional inference framework // Journal of Computational and Graphical Statistics. 2006. Vol. 15(3). P. 651-674.][Veytsman B., Akhmadeyeva L. Simple mathematical model of pathologic microsatellite expansions: when self-reparation does not work // Journal of Theoretical Biology. 2006. Vol. 242, № 2. P. 401-408.][Venables W.N., Ripley B.D. Modern Applied Statistics with S. Statistics and Computing. Springer, New York, fourth edition, 2010.]