Neurology BulletinNeurology Bulletin1027-48982304-3067Eco-Vector8967910.17816/nb89679Review (Book)Comt val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor (Science. — 2003. —Feb. 21. — 299(5610). — P. 1240—1243: англ.)ZubietaJ.<p>Department of Psychiatry and Mental Health Research Institute</p>info@eco-vector.comHeitzegM.<p>Department of Psychiatry and Mental Health Research Institute</p>info@eco-vector.comSmithY.<p>Department of Psychiatry and Mental Health Research Institute</p>info@eco-vector.comBuellerJ.<p>Department of Psychiatry and Mental Health Research Institute</p>info@eco-vector.comXuK.<p>Department of Psychiatry and Mental Health Research Institute</p>info@eco-vector.comXuY.<p>Department of Psychiatry and Mental Health Research Institute</p>info@eco-vector.comКоерреR.<p>Department of Psychiatry and Mental Health Research Institute</p>info@eco-vector.comStohlerC.<p>Department of Psychiatry and Mental Health Research Institute</p>info@eco-vector.comGoldmanD.<p>Department of Psychiatry and Mental Health Research Institute</p>info@eco-vector.comUniversity of Michigan20042003XXXV1-278780312202103122021Copyright © 2003, Zubieta J., Heitzeg M., Smith Y., Bueller J., Xu K., Xu Y., Коерре R., Stohler C., Goldman D.2003<p>The catechol-O-methyl-transferase (COMT) gene regulates the metabolic processes of the neurotransmitter dopamine and, through it, influences endorphins, which play an important role in the process of pain perception. It was found that the COMT gene with the amino acid valine (val158) is more active than the variant of the gene containing methionine (met158).</p>Bekhterev neurology archiveНеврологический архив Бехтерева