SPORADIC CEREBELLAR ATAXIA OF ELDERLY AGE:CLASSIFICATION, CRITERIA OF DIAGNOSIS



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Abstract

In the article modern representations, classification and diagnostic criteria of cerebellar ataxia of late age with the sporadic onset are stated; features of clinic, diagnostics and treatment of symptomatic (acquired or secondary) neurodegenerative processes of a cerebellum are considered; the characteristic of pathogenetic and morphological aspects of development local cortical cerebellar atrophy at persons of late age is given. For the characteristic of secondary acquired cerebellar degeneration the term «symptomatic cerebellopathy» is offered, allowing to distinguish local cortical atrophy of cerebellum and immediate spinocerebellar degenerative diseases hereditary and idiopathic origin.

About the authors

Gulnara R Khuzina

Каzan state medical university

Email: gkhuzina@yandex.ru
кафедра неврологии и реабилитации; Казанский государственный медицинский университет; Каzan state medical university

Enver I Bogdanov

Каzan state medical university

кафедра неврологии и реабилитации; Казанский государственный медицинский университет; Каzan state medical university

References

  1. Brusse E., Maat-Kievit J.A., van Swieten J.C. Diagnosis and management of early- and late-onset cerebellar ataxia // Clin. Genet. - 2007. - № 71. - P. 12-24.
  2. Muzaimi M.B., Thomas J., Palmer-Smith S. et al. Population based study of late onset cerebellar ataxia in south east Wales // J. Neurol Neurosurg Psychiatry. - 2004. - № 75. - P. 1129-34.
  3. Berciano J., Boesch S., Perez-Ramos J.M., Wenning G.K. Olivopontocerebellar atrophy: toward a better nosological defi nition // Mov Disord. - 2006. - № 21. - Р. 1607-13.
  4. Fogel B.L., Perlman S. An approach to the patient with late-onset cerebellar ataxia // Nat Clin Pract Neurol. - 2006. - №2. - Р. 629-635.
  5. Fogel B.L., Perlman S. Сlinical features and molecular genetics of autosomal recessive cerebellar ataxias // Lancet Neurol. - 2007. - №6. - С.245-257.
  6. Mancall E.L. Late (acquired) cortical cerebellar atrophy // Vinken P.S., Bruyn G.W. Handbook of clinical neurology. - Amsterdam: Elsevier, 1975. - Vol. 22. - P. 477-508.
  7. Klockgether T., Schroth G., Diener H.C., Dichgans J. Idiopathic cerebellar ataxia of late onset: natural history and MRI morphology // J. Neurol Neurosurg Psychiatry. - 1990. - № 53. - P. 297-305.
  8. Klockgether T. Sporadic ataxia with adult onset: classification and diagnostic criteria // Lancet neurol. - 2010. - № 9. - P. 94-104.
  9. Ramos A., Quintana F., Diez C. et al. CT findings in spinocerebellar degeneration // AJNR Am. J. Neuroradiol. - 1987. - №8. - P. 635-40.
  10. Victor M., Adams R.D., Mancall E.L. A restricted form of cerebellar cortical degeneration occurring in alcoholic patients // Arch Neurol. - 1959. - №1. - P. 579-688.
  11. Estrin W.J. Alcoholic cerebellar degeneration is not a dose-dependent phenomenon // Alcohol Clin Exp Res. - 1987. - №11. - P. 372-375.
  12. Gilman S., Adams K., Koeppe R. et al. Cerebellar and frontal hypometabolism in alcoholic cerebellar degeneration studied with positron emission tomography // Ann. Neurol. - 1990. - №28. - P.775-785.
  13. Gilman S., Koeppe R., Adams K. et al. PET studies of cerebral benzodiazapine receptor binding in chronic alcoholics // Ann. Neurol. - 1996. - № 40. - P. 163-171.
  14. Torvik A., Torp S. The prevalence of alcoholic cerebellar atrophy. A morphometric and histological study of an autopsy materia // J. Neurol Sc. - 1986. - №75. - P. 43-51.
  15. Yokota O., Tsuchiya K., Terada S. et al. Frequency and clinicopathological characteristics of alcoholic cerebellar degeneration in Japan: a cross-sectional study of 1,509 post-mortems // Acta Neuropathol. - 2006. - №112. - P. 43-51.
  16. Johnson-Greene D., Adams K.M., Gilman S. et al. Impaired Upper Limb Coordination in Alcoholic Cerebellar Degeneration // Arch Neurol. - 1997. - Vol.54. - №4. - P. 436-439.
  17. Melgaard B., Ahlgren P. Ataxia and cerebellar atrophy in chronic alcoholics // J. Neurol. - 1986. - № 233. - P. 13-15.
  18. Das S.K., Dhanya L., Vasudevan D.M. Biomarkers of alcoholism: an updated review // Scand J. Clin Lab Invest. - 2008. - № 68. - Р. 81-92.
  19. Posner J.B., Dalmau J.O. Paraneoplastic syndromes of the nervous system // Clin Chem La Med. - 2000. - № 38. - P. 117-122.
  20. Bolla L., Palmer R.M. Paraneoplastic cerebellar degeneration. Case report and literature review // Arch Intern Med. - 1997. - № 157. - P. 1258-1262.
  21. Baloh R.W. Paraneoplastic cerebellar disorders // Otolaryngol-Head-Nech-Surg. - 1995. -№1. - P. 125-127.
  22. Brock S., Ellison D., Frankel J. et al. Anti-Yo antibody-positive cerebellar degeneration associated with endometrial carcinoma: case report and review of the literature // Clin. Oncol. (Royal College of Radiologists). - 2001. - №13. - P. 476-479.
  23. Bradwell A.R. Paraneoplastic neurological syndromes associated with Yo, Hu, and Ri autoantibodies // Clin. Rev. in Allergy Immunol. - 2000. - №19. - P. 19-29.
  24. Peterson K., Rosenblum M.K., Kotanides H., Posner J.B. Paraneoplastic cerebellar degeneration. I. A clinical analysis of 55 anti-Yo antibody positive patients // Neurology. - 1992. - № 42. - P. 1931-1937.
  25. Altermatt H.J., Rodrignez M., Scheithaner B.W., Len-non V.A. Paraneoplastic anti Purkinje and type 1 anti-neuronal nuclear autoantibodies bind selectively to central peripheral and autonimic nervous system cells // Lab. Invest. - 1991. - № 65. - P. 412-420.
  26. Anderson N.E., Rosenblum M.K., Posner J.B. Paraneoplastic cerebellar degeneration: clinicalimmunological correlations // Ann. Neurol. - 1988. - №24. - P. 559-567.
  27. Miyashita N., Nakajima M., Niki Y., Matsushima T. Small-cell carcinoma of the lung with paraneoplastic cerebellar degeneration // Nippon-Kyobu. - 1996. - №3. - P. 380-383.
  28. Moll J.M., Henzen-Logmans S.C., Van-der-Meche F.G., Vecht C.H. Early diagnosis and intravenous immune globulin therapy in paraneoplastic cerebellar degeneration // J. Neurol. Neurosurg. Psychiatry. - 1993. - №1. - P. 112.
  29. Cremer G.M., Goldsteen N.P., Paris J. Myxedema and ataxia // Neurology. - 1969. - № 1. - P. 37-46.
  30. Jellinek E.H., Kelly R.E. Cerebellar syndrome in myxoedema // Lancet 2. - 1960. - № 2. -P. 225.
  31. Price T.R., Netsky M.G. Myxedema and ataxia, cerebellar alterations and «neural myxedema bodies» // Neurology. - 1966. - № 16. - P. 957.
  32. Kores B., Lader M.H. Irreversible lithium neurotoxicity: an overview // Clin. europharmacol. - 1997. - № 20. - P. 283-99.
  33. De Marcos F.A., Ghizoni E., Kobayashi E. et al. Cerebellar volume and long-term use of phenytoin // Seizure. - 2003. - № 12. - P. 312-15.
  34. Orr C.F., Ahlskog J.E. Frequency, characteristics, and risk factors for amiodarone neurotoxicity // Arch. Neurol. - 2009. - № 66. - P. 865-69.
  35. Fornazzari L., Wilkinson D.A., Kapur B.M., Carlen P.L. Cerebellar, cortical and functional impairment in toluene abusers // Acta Neurol Scand. - 1983. - № 67. - P. 319-29.
  36. Bygrave H.A., Geh J.I., Jani Y., Glynne-Jones R. Neurological complications of 5-fluorouracil chemotherapy: case report and review of the literature // Clin Oncol (R Coll Radiol) - 1998. - № 10. - P. 334-336.
  37. Lazarus H.M., Herzig R.H., Herzig G.P. et al. Central nervous system toxicity of high-dose systemic cytosine arabinoside // Cancer. - 1981. - № 48. - P. 2577-2582.
  38. Waring W.S. Management of lithium toxicity // Toxicol Rev. - 2006. - № 25. - P. 221-30.
  39. Pirzada N.A., Ali I.I., Dafer R.M. Fluorouracil-induced neurotoxicity // Ann. Pharmacother. - 2000. - № 34. - P. 35-38.
  40. Honnorat J., Saiz A., Giometto B. et al. Cerebellar ataxia with anti-glutamic acid decarboxylase antibodies: study of 14 patients // Arch. Neurol. - 2001. - №58. - P. 225-30.
  41. Manto M.U., Laute M.A., Aguera M. et al. Eff ects of anti-glutamic acid decarboxylase antibodies associated with neurological diseases // Ann Neurol. - 2007. - № 61. - P. 544-51.
  42. Abele M., Weller M., Mescheriakov S. et al. Cerebellar ataxia with glutamic acid decarboxylase autoantibodies // Neurology. - 1999. - № 52. - P. 857-59.
  43. Lauria G., Pareyson D., Pitzolu M.G., Bazzigaluppi E. Excellent response to steroid treatment in anti-GAD cerebellar ataxia // Lancet Neurol. - 2003. - № 2. - P. 634-635.
  44. Nanri K., Okita M., Takeguchi M. et al. Intravenous immunoglobulin therapy for autoantibody-positive cerebellar ataxia // Intern Med. - 2009. - № 48. - P. 783-90.
  45. Briani C., Samaroo D., Alaedini A. Celiac disease: from gluten to autoimmunity // Autoimmun Rev. - 2008. - № 7. - P. 644-50.
  46. Hadjivassiliou M., Grunewald R.A., Chattopadhyay A.K. et al. Clinical, radiological, neurophysiological, and neuropathological characteristics of gluten ataxia // Lancet. - 1998. - № 352. - P. 1582-1585.
  47. Pellecchia M.T., Scala R., Filla A. et al. Idiopathic cerebellar ataxia associated with celiac disease: lack of distinctive neurological features // J. Neurol Neurosurg Psychiatry. - 1999. - № 66. - P. 32-35.
  48. Burk K., Busch S., Meller C.A. et al. Sporadic cerebellar ataxia associated with gluten sensitivity // Brain. - 2001. - № 124. - P. 1013-1019.
  49. Abele M., Burk K., Schols L. et al. The aetiology of sporadic adult-onset ataxia // Brain. - 2002. - № 125. - P. 961-968.
  50. Abele M., Minnerop M., Urbach H. et al. Sporadic adult onset ataxia of unknown etiology: a clinical, electrophysiological and imaging study // J. Neurol. - 2007. - № 254. - P. 1384-1389.

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