Current Pharmaceutical BiotechnologyCurrent Pharmaceutical BiotechnologyCurrent Pharmaceutical Biotechnology1389-20101873-4316Bentham Science64530410.2174/0113892010279151240116103917BiotechnologyResearch ArticleTraditional Chinese Medicine-based Treatment in Cardiovascular Disease: Potential Mechanisms of ActionLiLanlaninfo@benthamscience.netRanYutonginfo@benthamscience.netWenJiaoinfo@benthamscience.netLuYiruiinfo@benthamscience.netLiuShunmeiinfo@benthamscience.netLiHonginfo@benthamscience.netChengMininfo@benthamscience.netSchool of Basic Medicine Sciences, Weifang Medical University0109202425172186219907012025Copyright ©; 2024, Bentham Science Publishers2024Bentham Science Publishershttps://journals.eco-vector.com/1389-2010/article/view/645304

:Cardiovascular Disease (CVD) is the leading cause of morbidity and death worldwide and has become a global public health problem. Traditional Chinese medicine (TCM) has been used in China to treat CVD and achieved promising results. Therefore, TCM has aroused significant interest among pharmacologists and medical practitioners. Previous research showed that TCM can regulate the occurrence and development of atherosclerosis (AS), ischemic heart disease, heart failure, myocardial injury, and myocardial fibrosis by inhibiting vascular endothelial injury, inflammation, oxidant stress, ischemia-reperfusion injury, and myocardial remodeling. It is well-known that TCM has the characteristics of multi-component, multi-pathway, and multitarget. Here, we systematically review the bioactive components, pharmacological effects, and clinical application of TCM in preventing and treating CVD.

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