Treatment of endotoxinemia syndrome in patients with atopic dermatitis

Abstract


The role of endotoxin in pathogenesis of atopic dermatitis (AD) is discussed. A total of 81 patients with AD were examined (68 men and 13 women from 16 to 53 years old). In 60% of patients disorders of gastro-intestinal tract were diagnosed, in 90% of subjects disbalance of gastrointestinal microflora was detected. In all patients mean level of endotoxin (lipopolyssacharide) in blood was above normal. A pathogenetic method of AD treatment is suggested including enterosorbents, probiotics, and hepatoprotectors.

References

  1. Кан А. Е., Осин А. Я. // Соврем. наукоемкие технол. - 2006. - № 7. - С. 27-31.
  2. Прохоренко И. Р., Белков Д. А. // Мед. иммунол. - 2003. - № 3. - С. 213-214.
  3. Текучева Л. В. Терапия детей, больных атопическим дерматитом, с учетом степени бактериальной обсемененности кожи и тяжести течения заболевания: Автореф. дис. ... канд. мед. наук. - М., 2009.
  4. Яковлев М. Ю. Системная эндотоксинемия в физиологии и патологии человека: Автореф. дис. ... д-ра мед. наук. - М., 1993.
  5. Яковлев М. Ю. // Физиол. человека. - 2003. - Т. 29, № 4. - С. 98-109.
  6. Alexander Ch., Rietshel E. // J. Endotoxin. Res. - 2001. - Vol. 7, N 3. - P. 167.
  7. Schultz Larsen F., Svensson A., Diepgen T. L. et al. // Acta Dermatol. Venerol. - 2005. - Vol. 85. - P. 1.

Statistics

Views

Abstract - 17

Cited-By


Article Metrics

Metrics Loading ...

PlumX

Dimensions


Copyright (c) 2011 Fedorova Y.S., Vasenova V.Y., Butov Y.S., Fyodorova Y.S., Vasyonova V.Y., Butov Y.S.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies