Morfologicheskie rezul'taty primeneniya kletochnykh tekhnologiy dlya korrektsii lineynoy atrofii kozhi (striy)

Abstract


Whether autologous peripheral blood multipotent hemopoietic cells (APBMHC) may be used to correct striae after pregnancy was studied. The first visual signs of the better appearance of atrophic scars are seen 1.5-2 months after administration of APBMHC and gradually progress up to 6 months. Light microscopic methods showed epithelial atrophy, hyperkeratosis and sclerosis of all layers of the derma with smoothing of papillae, fewer blood vessels and skin appendages in the striae cutis distensae prior to treatment. After using APBMHC, in all cases the connective tissue at the site of the derma displayed an increase in the number of vessels due to neoangiogenetic processes, a reduction in the degree of leukocyte infiltration, the thinning of collagen and elastin fibers and their straightening-out, which permits a more successful use of cosmetic procedures to correct these skin defects.

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