CONFOCAL SCANNING LASER MICROSCOPY IN ASSESSING THE EFFICACY OF AUTOLOGOUS PLATELET-ENRICHED PLASMA WHEN CORRECTING AGE-RELATED CHANGES IN FACIAL SKIN

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Abstract


The efficacy of using autologous platelet-enriched plasma (auto-OTP) in women of different age groups with involutionally altered facial skin by the method of confocal laser scanning microscopy was evaluated. Own results of treatment of 50 patients aged from 35 to 55 years with clinical manifestations of involutionally altered facial skin are presented. As a result of the therapy, a decrease in the clinical signs of aging was observed in all women, but the clinical effect was more pronounced in the age group from 35 to 45 years (97%, of which 76% was significant improvement, 21% was improvement). In the second group (46-55 years), the decrease in clinical signs of aging after the course of procedures was observed in 86%, of which a significant improvement was in 39%, improvement in 47%, without effect 14%. With the help of confocal laser scanning microscopy it was established that in all patients the intradermal administration of auto-OTP promoted the improvement of the structural and functional organization of the epidermis and dermis, increasing the thickness of the dermal layer. The received data testify to high efficiency and safety of application of auto-OTP in correction of involutional skin changes.

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About the authors

Olga Yu. Olisova

First Moscow State Medical University n.a. I.M. Sechenov (Sechenovsky University)

Email: Olisovaolga@mail.ru
Moscow, 119991, Russian Federation
MD, PhD, DSc., professor, head of Department of Skin and Sexually Transmitted Diseases of First Moscow State Medical University n.a. I.M. Sechenov (Sechenovsky University), Moscow, 119991, Russian Federation

A. D Karagadyan

First Moscow State Medical University n.a. I.M. Sechenov (Sechenovsky University)

Moscow, 119991, Russian Federation

L. G Garanyan

First Moscow State Medical University n.a. I.M. Sechenov (Sechenovsky University)

Moscow, 119991, Russian Federation

A. S Allenova

First Moscow State Medical University n.a. I.M. Sechenov (Sechenovsky University)

Moscow, 119991, Russian Federation

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Copyright (c) 2017 Olisova O.Y., Karagadyan A.D., Garanyan L.G., Allenova A.S.

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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