Email this article Transdermal redermalization in rosacea: Rehab procedures in intercurrent period
- Authors: Romashkina A.S.1, Olisova O.Y.2, Snarskaya E.S.2
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Affiliations:
- LLC Beauterra
- I.M. Sechenov First Moscow State Medical University (Sechenov University)
- Issue: Vol 23, No 3 (2020)
- Pages: 182-187
- Section: CLINICAL PICTURE, DIAGNOSIS, AND THERAPY OF DERMATOSES
- Submitted: 02.11.2020
- Accepted: 02.11.2020
- Published: 15.06.2020
- URL: https://rjsvd.com/1560-9588/article/view/48901
- DOI: https://doi.org/10.17816/dv48901
- ID: 48901
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Abstract
Background: The authors presented their own experiences of skin restoration in patients with rosacea after a course of active therapy using transdermal redermalization.
Aim: The course of cosmetic correction procedures using this method aimed to restore the energy potential of cells, water balance, and structures of the dermal elastin fibers, normalize microcirculation processes, and create an optimal physiological environment for the mitotic activity of epidermal cells.
Materials and methods: An innovative method of transdermal redermalization represents the administration of a drug containing hyaluronic acid and sodium succinate using the technique of papular intradermal injections, taking into account the peculiarities of lymphatic drainage in the facial area.
Results: To assess the therapy’s efficiency, noninvasive monitoring of changes in morphological structures of the skin was performed using confocal laser scanning microscopy.
Conclusions: The authors revealed the high efficiency of the method, which controls the remission state for a long term, subsequently avoiding drug therapy
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About the authors
Anastasia S. Romashkina
LLC Beauterra
Author for correspondence.
Email: RomashkinaAS@mail.ru
ORCID iD: 0000-0002-6775-9797
MD, PhD, Medical director of Limited liability company Beauterra
Russian Federation, MoscowO. Y. Olisova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: RomashkinaAS@mail.ru
ORCID iD: 0000-0003-2482-1754
Russian Federation, Moscow
E. S. Snarskaya
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: RomashkinaAS@mail.ru
ORCID iD: 0000-0002-7968-7663
Russian Federation, Moscow
References
- Tan J, Steinhoff M, Berg M, Del Rosso J, Layton A, Leyden J, et al.; Rosacea International Study Group. Shortcomings in rosacea diagnosis and classification. Br J Dermatol. 2017;176(1):197-9.
- Picardo M, Ottaviani M. Skin microbiome and skin disease: the example of rosacea. J Clin Gastroenterol. 2014;48(Suppl.1):85-6.
- Rusina TS, Snarskaya ES. Erythematotelangiectatic rosacea: the optimization of diagnostics and therapy. Russian Journal of Skin and Venereal Diseases. 2019;22 (3-4):111-20. (in Russian)
- Araviyskaya ER, Samtsov AV. Federal clinical guidelines of therapy of patients with rosacea. Moscow: Russian Society of Dermatologists and Cosmetologists; 2015. (in Russian)
- Khayrutdinov VR. Rosacea: modern concepts of the pathogenesis, clinical picture and treatment. Effective pharmacology. 2014;(19):32-7 (in Russian)
- Steinhoff M, Schmelz M, Schauber J. Facial erythema of rosacea – aetiology, different pathophysiologies and treatment options. Acta Derm Venereol. 2016;96(5):579-86.
- Steinhoff M, Schauber J, Leyden JJ. New insights into rosacea pathophysiology: a review of recent findings. J Am Acad Dermatol. 2013;69(6, Suppl. 1):S15-26.
- Ariza AC, Deen PM, Robben JH. The succinate receptor as a novel therapeutic target for oxidative and metabolic stress-related conditions. Front Endocrinol (Lausanne). 2012;3:22.
- Lukyanova LD, Kirova Yu I, Germanova EL. Specific features of immediate expression of succinate-dependent receptor GPR91 in tissues during hypoxia. Bull Exp Biol Med. 2016;160(6):742-7.
- Rubic T, Lametschwandtner G, Jost S, Hinteregger S, Kund J, Carballido-Perrig N., et al. Triggering the succinate receptor GPR91 on dendritic cells enhances immunity. Nat Immunol. 2008;9(11):1261-9.
- Liskina IV, Derkach NN, Kuzovkova SD. Comparative clinical and morphological study of the effect of two hyaluronic acid based products on the skin. Ukrainian Journal of Dermatology, Venereology, Cosmetology. 2010;(2):64-70. (in Russian)
- Ulusal B. Platelet-rich plasma and hyaluronic acid - an efficient biostimulation method for face rejuvenation. J Cosmet Dermatol. 2017;16(1):112-9.
- Grant-Kels JM, Pellacani G, Longo C. Reflectance confocal microscopy clinical applications: the skin from inside. Dermatol Clin. 2016;34(4):xiii–xiv.
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