Modern ideas about the sclerosing lichen of the vulva

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Abstract

Lichen sclerosus (LS) is a chronic inflammatory disease that is 6-10 times more common in women than in men. The drug affects between 1 in 1000 and 1 in 300 people in the general population, but the exact prevalence is unknown due to the fact that the disease is often asymptomatic. The article presents modern ideas about lichen sclerosus. Issues of various etiological theories of origin and pathogenesis are considered. The description of the clinical picture of lichen sclerosus is given. Diagnostic approaches are described, including the histological picture. Possible complications, including anatomical abnormalities of the vulvar architectonics and the risk of malignant transformation, are discussed in detail. Various methods of treatment and care for this disease, local treatment schemes are presented, an overview of systemic drugs and surgical operations, as well as further observation and management of patients is given.

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About the authors

Sergey I. Surkichin

Central State Medical Academy of Department of Presidential Affairs

Author for correspondence.
Email: surkichinsi24@mail.ru
ORCID iD: 0000-0003-0521-0333

Cand. Sci. (Med.), Associate Professor

Russian Federation, 19 Marshala Timoshenko str., Moscow, 121359

Larisa S. Kruglova

Central State Medical Academy of Department of Presidential Affairs

Email: kruglovals@mail.ru
ORCID iD: 0000-0002-5044-5265
SPIN-code: 1107-4372

Dr. Sci. (Med.)

Russian Federation, 19 Marshala Timoshenko str., Moscow, 121359

Inna A. Apolikhina

Research Center for Obstetrics, Gynecology and Perinatology

Email: apolikhina@inbox.ru
ORCID iD: 0000-0002-4581-6295
SPIN-code: 6282-7435

Dr. Sci. (Med.), Professor

Russian Federation, 19 Marshala Timoshenko str., Moscow, 121359

Roman Yu. Mayorov

Central State Medical Academy of Department of Presidential Affairs

Email: roman1396@bk.ru
ORCID iD: 0000-0003-1911-6743

MD

Russian Federation, 19 Marshala Timoshenko str., Moscow, 121359

Marika Avin

Medical center “Stolitsa”

Email: marika.avin@gmail.com
ORCID iD: 0000-0002-8317-0800

MD

Russian Federation, 19 Marshala Timoshenko str., Moscow, 121359

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
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