Russian Journal of Skin and Venereal DiseasesRussian Journal of Skin and Venereal Diseases1560-95882412-9097Eco-Vector3674610.17816/dv36746Research ArticleOn the treatment of relapsing basal-cell carcinoma of the skinMolochkovV. A-KhlebnikovaA. Nalb9696@yandex.ruAlievaP. M-SedovaT. G-SeleznevaE. V-I.M.Setchenov First Moscow State Medical University150620131636921072020Copyright © 2013, Eco-Vector2013Relapsing basal-cell carcinoma was treated by the application method with Mardil Selen. Seven nodular ulcerative basal-cell carcinomas with mainly the micronodular structure were removed by applications of Mardil Selen. The treatment efficiency reached 85.7%. Satisfactory cosmetic results of treatment were confirmed by ultrasonic scanning, indicating recovery of the homogeneous structure of the derma.basal-cell carcinomatherapyMardil Selenultrasonic scanningбазалиомарецидивлечениеМардил СеленУЗ-сканирование[Stanley R.BJr., Burres S.A., Jacobs J.R., Mathod R.H. Hazards encountered in management basal cell carcinoma of the midface. Laringoscope. 1984; 94(3): 378-85.][Снарская Е.С., Молочков В А. Базалиома. М.: Медицина; 2003.][Lang P.G., Maize J.C. Basal cell carcinoma. In: Friedman R.J. et al., eds. Cancer of the skin. Philadelphia: W.B.Saunders Company; 1991: 35-73.][Crowson A.N. Basal cell carcinoma: biology, morphology and clinical implications. Mod. Pathol. 2006; 19 (Suppl. 2): S127-S147.][Boeta-Angeles L., Bennett R.G. Features associated with recurrence. In: Miller S.J., Maloney M.E., eds. Cutaneous Oncology: Pathophysiology, Diagnosis, and Management. Malden, MA: Blackwell Science, Inc.; 1998: 646-56.][Sexton F.M., Jones D.B., Maloney M.E. Histological pattern analysis of basal cell carcinoma. J. Am. Acad. Dermatol. 1990; 23(6, Pt. 1): 1118-26.][Breuninger H., Dietz K. Prediction of subclinical tumor infiltration in basal cell carcinoma. J. Dermatol. Surg. Oncol. 1991; 17(7): 574-8.][Silverman M.K., Kopf A.W., Bart R.S., Grin C.M., Levenstein M.S. Reccurence rates of treated basal cell carcinomas. Part 3: surgical excision. J. Dermatol. Surg. Oncol. 1992; 18(6): 471-6.][Lang N.P., Kendrick J.H., Flaningin H., Wetmore S.J., Suen J.Y., Westbrook K.C. Surgical management of advanced scalp cancer. Head. Neck. Surg. 1983; 5(4): 299-305.][Leferink V.J., Nicolai J.P. Malignant tumor of the external ear. Ann. Plast. Surg. 1988; 21(6): 550-5.][Ashby M.A., Smith J., Ainslie J., McEwan L. Treatment of nonmelanoma skin cancer at a large Australian center. Cancer. 1989; 63(9): 1863-71.][Silverman M.K., Kopf A.W., Bart R.S. Gladstein A.H., Grin C.M., Levenstein M.J. Reccurence rates of treated basal cell carcinomas. Part 4: X-ray-therapy. J. Dermatol. Surg. Oncol. 1992; 18(7): 549-54.][Wilson J.S.P., Blake G.B., Richardson A.E., Westbury G. Malignant tumours of the ear and their treatment. II. Tumours of the external auditory meatus, middle ear cleft and temporal bone. Br. J. Plast. Surg. 1974; 27(1): 77-91.][Salasche S.J. Curettage and electrodissecation in the treatment of midfacial basal cell epithelioma. J. Am. Acad. Dermathol. 1983; 8(4): 496-503.][Freemann R.G., Duncan C. Reccurent skin cancer. Arch. Dermatol. 1973; 107(3): 395-9.][Rowe D.E., Carroll R.J., Day C.L.Jr. Long-term recurrence rates in previously untreated (primary) basal cell carcinoma: implication for patient follow-up. J. Dermatol. Surg. Oncol. 1989; 15(3): 315-28.][Torre D. Criosurgery of basal cell carcinoma. J. Am. Acad. Dermatol. 1986; 15(5, Pt 1): 917-29.][Dellon A.L., Potvin C., Chretien P.B., Rogentine N.C. The immunobiology of skin cabcer. Plast. Reconstr. Surg. 1975; 55(3): 341-54.][Dickie W.R., Hughes N.C. Caustic pastes: the survival as quack cancer remedies. Br. J. Plast. Surg. 1961; 14(2): 97-109.][Laughlin S.A., Dudley D.K. Historical survey methods used to treat skin cancer. In: Schwartz R.A., ed. Chapter 20. Historical Survey: Methods Used to Treat Skin Cancer. Skin Cancer: Recognition and Management. Blackwell Publishers; 2008: 350-66.][Kuflik E.G. Criosurgery. In: Miller S.J., Maloney M.E., eds. Cutaneous Oncology: Pathophysiology, Diagnosis, and Management. Malden, MA: Blackwell Science, Inc.; 1998: 672-5.]