Russian Journal of Skin and Venereal DiseasesRussian Journal of Skin and Venereal Diseases1560-95882412-9097Eco-Vector3733510.18821/1560-9588-2018-21-1-16-18Research ArticleCUTANEOUS LYMPHOID HYPERPLASIA PROVOKED BY RED PIGMENT OF TATTOOKuklinIgor A.MD, PhD, docent, Ural Research Institute of Dermatovenerology and Immunopathology, Ekaterinburg, 620076, Russian Federationkuklin71@mail.ruVolkovaN. V-KokhanM. M-SafonovaG. D-SorokinaN. D-Ural Research Institute of Dermatovenerology and ImmunopathologyClinic of laser cosmetology «Linline»15022018211161821072020Copyright © 2018, Eco-Vector2018The data of the prevalence and clinical features of adverse «Tatto reactions» are shown. The case report of cutaneous lymphoid hyperplasia which was provoked by red pigment of tattoo is presented.adverse tatto reactionsred pigment of tattoocutaneous lymphoid hyperplasiaнежелательные реакции на татуировкикрасная татуировкакожная лимфоидная гиперплазия[Serup J., Carlsen K.H., Sepehri M. Tattoo complaints and complications diagnosis and clinical spectrum. Curr. Probl. Dermatol. 2015; 26(48): 48-60.][Lauman A.E., Derick A.J. Tattos and body piercings in the United States: a national data set. J. Am. Acad. Dermatol. 2006; 55(3): 413-21.][Klugl I., Hiller K.A., Landthaler M., Baumler W. Incidence of health problems associated with tattoed skin: a nation-wide survey in German-speaking countries. Dermatology. 2010; 221(1): 43-50.][Kluger N. Cutaneous complications related to Tattoss: 31 cases from Finland. Dermatology. 2017; 233(1): 100-9.][Малишевская Н.П., Кохан М.М., Соколова А.В., Куклин И.А., Сафонова Г.Д., Пазина М.В. и др. Дерматоонкология (злокачественные новообразования кожи, первичные лимфомы кожи): Атлас. Екатеринбург: Изд-во Уральского университета; 2016.][Олисова О.Ю., Теплюк Н.П., Гаранян Л.Г., Пятилова П.М. Доброкачественная лимфоплазия кожи, развившаяся на месте татуировки. Российский журнал кожных и венерических болезней. 2015; 18(2); 23-5.][Tammaro A., Romano I., Parisella F. A case of Koebner phenomenon in a patient with tatto to lips. J. Cosmet. Laser Ther. 2016; 22: 1-7.][Mlakar B. Successful removal of hyperkeratotic-reaction to red ink tatto with preservation of the whole tatto using a skin grafting knife. Acta Dermatovenerol. 2015; 24(4): 81-2.][Kazlouskaya V., Jacqueline M., Junkins-Hopkins. Pseudoepitheliomatous hyperplasia in a Red Pigment Tatto. A separate entity or hipertrophic liche planus-like reaction? J. Clin. Aesthet. Dermatol. 2015; 8(12): 48-52.][Breza T.S., O’Brein A.K., Glavin F.L. Pseudoepitheliomatous hyperplasia: an unusual tatto reaction. JAMA Dermatol. 2013; 149(5): 630-1.][Bhogal R.H., Thomas S.S. Necrotizing black tatto reaction: what’s in a name? Am. J. Clin. Dermatol. 2009; 10(2): 131-3.][Ross E.V., Yashar S., Michaud N., Fitzpatrick R., Geronemus R., Tope W.D., et al. Tatto darkening and nonresponse after laser treatment: a possible role for titanum dioxide. Arch. Dermatol. 2001; 137(1): 33-7.][Aberer W., Snauwaert J.E., Render U.M. Allergic reaction to pigments and metals. In: de Cuyper C., Perez-Cotapos M.L.S. eds. Dermatologic complications with body art: tattoos, piercings and permanent make up. Belgium: Springer Link; 2010: 66-73.][Forte G., Petrucci F., Cristaudo A., Bocca B. Market survey on toxic metals contained in tatto inks. Sci. Total. Environ. 2009; 407(23): 5997-6002.][Sowden J.M., Byrne J.P., Smith A.G., Hiley C., Suarez V., Wagner B., et al. Red tattoo reactions: X-ray tattoo microanalysis and patch-test studies. Br. J. Dermatol. 1991; 124(6): 576-80.][Engel E., Santarelli F., Vasold R., Baumler W. Modern tattoos cause high concentrations of hazardous pigments in skin. Contact dermatitis. 2008; 58(4): 228-33.][Sulzberger M.B. Tattoo dermatitis (sensitivity to cinnabar?). Arch. Dermat. Syph. 1937; 36: 1265.][Goldberg H.I. Mercurial reaction in a tattoo. Can. Med. Assoc. J. 1959; 80(1): 203-4.][Balfour E., Olhoffer I., Leffel D., Handerson T. Massive pseudoepithelomatous hyperplasia: an unusual reaction to a tattoo. Am. J. Dermatopathol. 2003; 25(4): 338-40.][Cui W., McGregor D.H., Stark S.P., Ulusarac O., Mathur S.C. Pseudoepitheliomatous hyperplasia - an unusual reaction following tatto: report of a case and review of the literature. Int. J. Dermatol. 2007; 46(7): 743-5.][Kluger N., Durand L., Minier-Thoumin C., Plantie F., Cotton H., Berteloot E., et al. Pseudoepitheliomatous epidermal hyperplasia in tattos: report of three cases. Am. J. Clin. Dermatol. 2008; 9(5): 337-40.][Goldstein N. Mercury-cadmium sensitivity in tattoos. A photoallergic reaction in red pigment. Ann. Intern. Med. 1967; 67(5): 984-9.]