Vol 14, No 1 (2011)

Articles
Lymphomatoid granulematosis
Molochkov V.A., Kovrigina A.M., Kazantseva I.A., Ovsyannikova G.V., Groznova A.A., Fedorovskaya A.V., Bobrov M.A., Molochkov V.A., Kovrigina A.M., Kazanzeva I.A., Ovsyannikova G.V., Groznova A.A., Fedorovskaya A.V., Bobrov M.A.
Abstract
The paper presents review of literature and a case of rare form of B-cell lymphoma involving the skin - lymphomatoid granulomatosis in a 49 years old patient. The diagnosis was confirmed by clinical, histologic, immunohistochemical and molecular-biological examination.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):4-6
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Spectrum of autoimmune disorders in paraneoplastic pemphigus
Makhneva N.V., Beletskaya L.V., Makhneva N.V., Belezkaya L.V.
Abstract
Results of indirect immunofluorescence analysis of curculating autoantibodies in paraneoplastic pemphigus and investigation of their role in development of this disease are presented. It was estimated that a wide variety of IgG autoantibodies play a role in manifestation of paraneoplastic pemphigus. Pathologic process involves not only desmosomal apparatus of stratified squamose epithelium and Hassal's bodies but also of parenchymatous organs, such as heart and liver. Detection of additional antibodies (particularly to antigens of discs in cross-striated muscles, myocardium capillaries, structures of conjunctive tissue in liver, and to nuclei of liver cells) in autoimmune pemphigus can raise a suggestion about paraneoplastic nature of pemphigus . Mosaic character of antibodies allow to consider paraneoplastic pemphigus as a multiorgan syndrome.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):7-11
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Age-specific characteristics of skin diseases development
Sergeeva I.G., Yakubovich A.I., Novoselov V.S., Saldamaeva L.S., Novoselov A.V., Sergeeva I.G., Yakubovich A.I., Novosyolov V.S., Saldamaeva L.S., Novosyolov A.V.
Abstract
Persons at senile and advanced age apply to dermatologists more often than to other doctors for the correction of age-related changes. Authors analyzed the results of examination of 7795 patients aged from 6 months to 95 years old to detect correlations of involutory skin changes in patients with carbohydrate or lipid metabolism disorders as well as in thyroid gland dysfunction during gerontogenesis. Among them patients exposed to adverse environmental factors were included (n = 328, 60-96 years old). Results of the study showed that influence of anthropogenic environmental factors leads to predomination of such involutory skin changes as senile angiomas (46,3%) and lentigo (39,0%). The study showed that in advanced age a complex of proliferative, pigmented and vascular skin changes develop, which indicate the acting factor. Analysis of somatic comorbidities in skin disorders showed that in skin disorders 1,8 somatic disorder per patient are diagnosed; in diabetes mellitus - 2,2; in hypothyrosis - 2,8; in lipid metabolism disorders - 3,8. Thus, the frequency of somatic diseases increases in metabolic disorders, especially in lipid metabolism disorders.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):11-16
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Treatment of endotoxinemia syndrome in patients with atopic dermatitis
Fedorova Y.S., Vasenova V.Y., Butov Y.S., Fyodorova Y.S., Vasyonova V.Y., Butov Y.S.
Abstract
The role of endotoxin in pathogenesis of atopic dermatitis (AD) is discussed. A total of 81 patients with AD were examined (68 men and 13 women from 16 to 53 years old). In 60% of patients disorders of gastro-intestinal tract were diagnosed, in 90% of subjects disbalance of gastrointestinal microflora was detected. In all patients mean level of endotoxin (lipopolyssacharide) in blood was above normal. A pathogenetic method of AD treatment is suggested including enterosorbents, probiotics, and hepatoprotectors.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):16-20
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Modern aspects of psychopharmacotherapy in dermatologic practice
Dorozhenok I.Y., L'vov A.N., Bobko S.I., Dorozhenok I.Y., Lvov A.N., Bobko S.I.
Abstract
The most widely used method of treatment of mental disorders in dermatological practice is psychopharmacotherapy which includes a wide variety of psychotropic agents classified into different pharmacologic classes (antipsychotics, antidepressants, anxiolytics). First of all one should assess the structure and severity of mental disorder to decide where (in psychiatric or dermatologic in-patient department or in out-patient department) and how to treat the patient. In a dermatologic in-patient and out-patient departments modern effective and safe medications of first line are recommended. These drugs can be differently used according to a diafnosis of somatoform, depressive and anxious disorders.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):20-25
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Experience and analysis of tactical mistakes in application of "Advantan" in complex treatment of chronic dermatoses
Volkova E.N., Lange D.A., Rodina Y.A., Tarasova M.V., Volkova Y.N., Lange D.A., Rodina Y.A., Tarasova M.V.
Abstract
The structure and unique kinetics of "Advantan" are described. The results of study of therapeutic effectivity of different forms of this drug are presented; typical mistakes in prescription and application of "Advantan" are analyzed. The referred facts point to high effectivity and safety of "Advantan" in treatment of chronic dermatoses.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):25-29
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Clinical features of different forms of lichen planus
Molochkov V.A., Prokof'ev A.A., Pereverzeva O.E., Bobrov M.A., Molochkov V.A., Prokofiev A.A., Pereverseva O.E., Bobrov M.A.
Abstract
The clinical features of different forms of lichen planus are described according to results of examination of 208 patients, treated in department of dermatovenereology and dermatooncology of Moscow Regional Research and Clinical M.F. Vladimirsky Institute in 1999-2009. Analysis of 21 russian and foreign publications is presented.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):30-36
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Comparative effectiveness of narrow-band 311 nm UVB therapy of psoriasis
Olisova O.Y., Vladimirov V.V., Smirnov K.V., Talybova A.M., Olisova O.Y., Vladimirov V.V., Smirnov K.V., Talybova A.M.
Abstract
Results of treatment of 70 patients with psoriasis vulgaris with narrow-band phototherapy (UVB 311 nm) are presented. In 88,6% of patients clinical remission was achieved. Effectivity and safety of this therapeutic method was demonstrated. It was shown that 4 times a week regimen is equally effective as 3 times a week regimen and has a shorter duration.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):36-40
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Complex treatment of skin sarcoidosis using intracutaneous therapy
Snarskaya E.S., Kryazheva S.S., Surikova N.S., Snarskaya Y.S., Kryazheva S.S., Surikova N.S.
Abstract
The paper presents a review of 59 russian and foreign publications about etiology, pathogenesis, clinical features and therapy of skin sarcoidosis. Analysis of 41 case of skin sarcoidosis treated with intracutaneous therapy.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):40-45
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Scleroatrophic skin lesions associated with Borrelia infection
Molochkov V.A., Snarskaya E.S., Markelov M.L., Chekanova T.A., Karan' L.S., Romashkina A.S., Molochkov V.A., Snarskaya Y.S., Markelov M.L., Chekanova T.A., Karan L.S., Romashkin A.S.
Abstract
Authors present a review of 59 russian and foreign publications about association of scleroatrophic skin lesions with Borrelia infection. Analysis of 25 patients with different scleroatrophic skin lesions associated with Borrelia infection, detected during two-step examination (enzyme immunoassay, immunoblot) of 152 patients with this disorder.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):45-49
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Malassezia folliculitis
Khaldin A.A., Shkrebets S.V., Plieva L.R., Shestakova L.A., Murakhovskaya E.K., Khaldin A.A., Shkrebez S.V., Plieva L.R., Shestakova L.A., Murakhovskaya E.K.
Abstract
Authors present 3 cases of follicular malasseziosis of skin developed as a result of general decrease in immunity due to intake of broad-spectrum antibiotics and immunodepressants and pregnancy. Besides that the history of terminology, etiology, pathogenesis and clinical forms of the disease as well as methods of treatment are discussed.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):49-53
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Norwegian scabies
Kryazheva S.S., Snarskaya E.S., Sukhova T.E., Kryazheva S.S., Snarskaya Y.S., Sukhova T.E.
Abstract
The paper presents a review of 18 russian and foreign publications about peculiarities of pathogenesis, clinical presentation, diagnostics and treatment of rare atypical form of scabies - norwegian scabies. Authors present a case of this disease in 65 years old patient with severe comorbid internal disorders.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):53-55
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Treatment of primary and secondary pyoderma with "Gexicon" gel
Sukharev A.V., Bondar' O.I., Patrushev A.V., Smirnov K.V., Lopaskin A.V., Sukharev A.V., Bondar O.I., Patrushev A.V., Smirnov K.V., Lopaskin A.V.
Abstract
The latest published data about epidemiology, pathogenesis, classification, diagnostics and treatment of pyodermia are presented. Results of own study are demonstrated. Study sample included 25 patients with primary and secondary pyodermia. A complex clinical assessment was conducted in patients with this disorder regarding the effectivity of treatment with "Gexicon" (chlorhexidine) gel. The results of this study allow to draw a conclusion about high effectivity of monotherapy with this drug, which can be recommended for wide use not only in in-patient but also in out-patient departments.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):56-59
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What du you think about cosmetology?
Sergeev A.Y., Sergeev V.Y., Muracheva E.A., Sergeev A.Y., Sergeev V.Y., Muracheva E.A.
Abstract
Authors present results of on-line interview of dermatologists about cosmetology as a new specialty in nomenclature of health workers. Different estimations of auditory depending from sex, age, the year of graduation from higher educational medical institution, science-degree, employment and profile of practical work are revealed.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):60-65
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Methods of epilation and depilation in modern cosmetology
Korneva L.V., Sopko M.L., Korneva L.V., Sopko M.L.
Abstract
The modern methods of epilation and depilation used in practical cosmetology are reviewed. These methods include laser, photo- and electroepilation, thermolysis, ELOS-epilation and others.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):66-67
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Oxidative stress in pathogenesis of vitiligo
Lomonosov K.M., Esipov D.S., Babeshko O.A., Tatarenko A.Y., Lomonosov K.M., Esipov D.S., Babeshko O.A., Tatarenko A.Y.
Abstract
Authors present a short literature review of one of theories of vitiligo pathogenesis - theory of biochemical disorders due to oxidative stress. Results of investigation of oxidative stress biomarker 8-oxo-2-deoxyguanosin are presented.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):68-70
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Anticytokine therapy of psoriasis in dermatological practice (Rome, 13-16 June 2010)
Tarasenko G.N., Tarasenko G.N.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):70-71
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Karie's mystery
Monakhov S.A., Monakhov S.A.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):71-72
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Ulcerated necrotic skin lesions on legs
Khaldin A.A., Shkrebets S.V., Plieva L.R., Murakhovskaya E.K., Khaldin A.A., Shkrebez S.V., Plieva L.R., Murakhovskaya E.K.
Russian Journal of Skin and Venereal Diseases. 2011;14(1):1a-1a
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