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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Current Pediatric Reviews</journal-id><journal-title-group><journal-title xml:lang="en">Current Pediatric Reviews</journal-title><trans-title-group xml:lang="ru"><trans-title>Current Pediatric Reviews</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1573-3963</issn><issn publication-format="electronic">1875-6336</issn><publisher><publisher-name xml:lang="en">Bentham Science</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">645434</article-id><article-id pub-id-type="doi">10.2174/1573396318666220816093731</article-id><article-categories><subj-group subj-group-type="toc-heading"><subject>Medicine</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Short Term Effects of Inhalation Sedation on Child Dental Fear and Anxiety</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Bangash</surname><given-names>Madeeha</given-names></name><email>info@benthamscience.net</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Mustafa</surname><given-names>Laila</given-names></name><email>info@benthamscience.net</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Irshad</surname><given-names>Muhammad</given-names></name><email>info@benthamscience.net</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name><surname>Omer</surname><given-names>Qaiser</given-names></name><email>info@benthamscience.net</email><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><name><surname>Alam</surname><given-names>Mohammad</given-names></name><email>info@benthamscience.net</email><xref ref-type="aff" rid="aff5"/></contrib></contrib-group><aff id="aff1"><institution>Department of Paediatric Dentistry, Rehman College of Dentistry</institution></aff><aff id="aff2"><institution>Consultant Paediatric Dentistry, Shifa College of Dentistry</institution></aff><aff id="aff3"><institution>Department of Oral Pathology, Rehman College of Dentistry</institution></aff><aff id="aff4"><institution>, Special Care dentistry, Dr. Qaiser &amp; Associates Dental Practice,</institution></aff><aff id="aff5"><institution>Preventive Dentistry Department, College of Dentistry,, Jouf University</institution></aff><pub-date date-type="pub" iso-8601-date="2024-01-01" publication-format="electronic"><day>01</day><month>01</month><year>2024</year></pub-date><volume>20</volume><issue>1</issue><fpage>89</fpage><lpage>93</lpage><history><date date-type="received" iso-8601-date="2025-01-11"><day>11</day><month>01</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Bentham Science Publishers</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Bentham Science Publishers</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://journals.eco-vector.com/1573-3963/article/view/645434">https://journals.eco-vector.com/1573-3963/article/view/645434</self-uri><abstract xml:lang="en"><p id="idm46466589715872">Background:Dental procedures profoundly affect a child's dental fear and anxiety, ren-dering dental treatment difficult. Inhalation sedation with a mixture of nitrous oxide and oxygen (NO2/02) breathed through a nosepiece is a form of light conscious sedation widely used in appre-hensive children to help them relax and accept dental treatment. This, however, can have both short-and long-term effects on child dental fear and anxiety. This study aimed to assess the short-term immediate effect of inhalation sedation on child dental fear and anxiety scores.</p><p id="idm46466589719872">Methods:This analytical cross-sectional study was conducted at the Department of Paediatric Den-tistry at Rehman College of Dentistry, Peshawar, Pakistan, over a period of 1.9 years (January 2019- October 2020). A total of 171 children aged 6-11 years were selected with moderate to severe dental anxiety using the Child Fear Survey Schedule-Dental Subscale (CFSS-DS), requiring pulp therapy in at least one of their deciduous molars. Baseline anxiety scores were calculated using Venham Clinical Anxiety Score (VCAS) and Venham Picture test (VPT) with a dental check-up and fluoride application. VCAS and VPT scores were then assessed at the end of their scheduled second dental visit involving dental anaesthesia and inhalation sedation. VCAS and VPT scores at the end of treatment were compared with the baseline scores.</p><p id="idm46466589723840">Results:Out of 171 children, 86 were male and 85 were female, with a mean age of 7.77. Females showed a higher range of VCAS and VPT scores (p ≤0.001) compared to males. The VCAS and VPT scores declined just at the end of the second dental visit following dental anaesthesia with in-halation sedation (mean difference = 1.96 and 3.39, respectively), which was statistically significant (p ≤0.001).</p><p id="idm46466589728896">Conclusion:Inhalation sedation has a significant role in reducing child dental fear and anxiety in the short term.</p></abstract><kwd-group xml:lang="en"><kwd>Dental anxiety</kwd><kwd>dental fear</kwd><kwd>paediatric dentistry</kwd><kwd>inhalation sedation</kwd><kwd>VPT</kwd><kwd>VCAS.</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Alasmari AA, Aldossari GS, Aldossary MS. Dental anxiety in children: A review of the contributing factors. J Clin Diagn Res 2018; 12: SG01-3. doi: 10.7860/JCDR/2018/35081.11379</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Mendoza-Mendoza A, Perea MB, Yañez-Vico RM, Iglesias-Linares A. 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