Current Stem Cell Research & TherapyCurrent Stem Cell Research & TherapyCurrent Stem Cell Research & Therapy1574-888X2212-3946Bentham Science64556610.2174/011574888X271344231129053003MedicineResearch ArticleMechanisms of Stem Cells and Their Secreted Exosomes in the Treatment of Autoimmune DiseasesLinShu-Qianinfo@benthamscience.netWangKaiinfo@benthamscience.netPanXing-Huainfo@benthamscience.netRuanGuang-Pinginfo@benthamscience.net, Clinical College of the 920th Hospital of Kunming Medical UniversityBasic medical laboratory, 920 Hospital of Joint Logistic Support Force of the Chinese People Liberation Army0111202419111415142811012025Copyright ©; 2024, Bentham Science Publishers2024Bentham Science Publishershttps://journals.eco-vector.com/1574-888X/article/view/645566

:Stem cells play a therapeutic role in many diseases by virtue of their strong self-renewal and differentiation abilities, especially in the treatment of autoimmune diseases. At present, the mechanism of the stem cell treatment of autoimmune diseases mainly relies on their immune regulation ability, regulating the number and function of auxiliary cells, anti-inflammatory factors and proinflammatory factors in patients to reduce inflammation. On the other hand, the stem cell- derived secretory body has weak immunogenicity and low molecular weight, can target the site of injury, and can extend the length of its active time in the patient after combining it with the composite material. Therefore, the role of secretory bodies in the stem cell treatment of autoimmune diseases is increasingly important.

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