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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Bulletin of the Russian Military Medical Academy</journal-id><journal-title-group><journal-title xml:lang="en">Bulletin of the Russian Military Medical Academy</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российской военно-медицинской академии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1682-7392</issn><issn publication-format="electronic">2687-1424</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">58206</article-id><article-id pub-id-type="doi">10.17816/brmma58206</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Experimental trials</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Экспериментальные исследования</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Development of technology for producing essential fatty acids from hydrolysates of high-fat fish</article-title><trans-title-group xml:lang="ru"><trans-title>Разработка технологии получения эссенциальных жирных кислот из гидролизатов рыб повышенной жирности</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kuprina</surname><given-names>Elena E.</given-names></name><name xml:lang="ru"><surname>Куприна</surname><given-names>Елена Эдуардовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>doctor of technical sciences, professor</p></bio><bio xml:lang="ru"><p>доктор технических наук, профессор</p></bio><email>elkuprina@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Grishina</surname><given-names>Evgeniya S.</given-names></name><name xml:lang="ru"><surname>Гришина</surname><given-names>Евгения Сергеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>master’s student</p></bio><bio xml:lang="ru"><p>магистрант</p></bio><email>grishinas@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Yakkola</surname><given-names>Anastasia N.</given-names></name><name xml:lang="ru"><surname>Яккола</surname><given-names>Анастасия Николаевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>postgraduate student</p></bio><bio xml:lang="ru"><p>аспирант</p></bio><email>shokoladnitsa@list.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Manuilov</surname><given-names>Andrey N.</given-names></name><name xml:lang="ru"><surname>Мануйлов</surname><given-names>Андрей Николаевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>postgraduate student</p></bio><bio xml:lang="ru"><p>аспирант</p></bio><email>manu2@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Demidov</surname><given-names>Pavel I.</given-names></name><name xml:lang="ru"><surname>Демидов</surname><given-names>Павел Игоревич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>postgraduate student</p></bio><bio xml:lang="ru"><p>аспирант</p></bio><email>pademido@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ivnenko</surname><given-names>Yulia G.</given-names></name><name xml:lang="ru"><surname>Ивненко</surname><given-names>Юлия Георгиевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>master’s student</p></bio><bio xml:lang="ru"><p>магистрант</p></bio><email>tehnojul@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">National Research University of Information Technologies, Mechanics and Optics (ITMO)</institution></aff><aff><institution xml:lang="ru">Национальный исследовательский университет информационных технологий, механики и оптики (ИТМО)</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2021-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2021</year></pub-date><volume>23</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>119</fpage><lpage>130</lpage><history><date date-type="received" iso-8601-date="2021-01-14"><day>14</day><month>01</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-06-01"><day>01</day><month>06</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, Kuprina E.E., Grishina E.S., Yakkola A.N., Manuilov A.N., Demidov P.I., Ivnenko Y.G.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, Куприна Е.Э., Гришина Е.С., Яккола А.Н., Мануйлов А.Н., Демидов П.И., Ивненко Ю.Г.</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">Kuprina E.E., Grishina E.S., Yakkola A.N., Manuilov A.N., Demidov P.I., Ivnenko Y.G.</copyright-holder><copyright-holder xml:lang="ru">Куприна Е.Э., Гришина Е.С., Яккола А.Н., Мануйлов А.Н., Демидов П.И., Ивненко Ю.Г.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.eco-vector.com/1682-7392/article/view/58206">https://journals.eco-vector.com/1682-7392/article/view/58206</self-uri><abstract xml:lang="en"><p>The technology for obtaining biologically active substances of a lipoid nature, enriched with omega-3 acids, from waste from the processing of hydrobionts by means of electrochemical hydrolysis and cryoconcentration has been developed. A comparative analysis of the composition of wastes from cutting herring and trout is carried out, and the expediency of their use for obtaining biologically active substances of a lipoid nature is shown. A technological scheme has been developed and fat yields have been determined when it is obtained from fish waste by an electrochemical method. The fatty acid composition of the fat obtained by the electrochemical method has been determined. It was found that cryoconcentrated fat obtained from wastes from trout and herring cutting by the electrochemical method has a significantly increased content of omega-3 acids and, accordingly, biological value compared to edible and medical fish oil from the liver of the cod family. It was found that during cryoconcentration, the concentration of polyunsaturated fatty acids increases, reaching values close to 90%, which allows the resulting product to be classified as biologically active additives. It was shown by calculation that to create functional fish-based food products from fish of the salmon family, it is sufficient to introduce 4 g of the obtained biologically active additive per 100 g of the product. There is also an improvement in the organoleptic properties of foods from lean fish species. It has been shown that in order to meet 30% of the recommended daily intake of omega-3 acids in the development of functional food products based on rainbow trout and Atlantic herring, it is necessary to introduce 1.98 g and 1.8 g of cryoconcentrated fish oil. After encapsulation in nanocapsules, the drug will be suitable for enrichment with omega-3 acids in any food products, which is the subject of further research.</p></abstract><trans-abstract xml:lang="ru"><p>Разработана технология получения биологически активных веществ липоидной природы, обогащенных омега-3-кислотами, из отходов от переработки гидробионтов путем электрохимического гидролиза и криоконцентрирования. Проведен сравнительный анализ состава отходов от разделки сельди и форели и показана целесообразность их использования для получения биологически активных веществ липоидной природы. Разработана технологическая схема и определены выходы жира при его получении из отходов рыб электрохимическим способом. Определен жирнокислотный состав жира, полученного электрохимическим способом. Установлено, что криоконцентрированный жир, полученный из отходов от разделки форели и сельди электрохимическим способом, обладает существенно повышенным содержанием омега-3-кислот и, соответственно, биологической ценностью по сравнению с пищевым и медицинским рыбьим жиром из печени семейства тресковых. Установлено, что при криоконцентрировании концентрация полиненасыщенных жирных кислот возрастает, достигая значений, близких к 90%, что позволяет отнести полученный продукт к биологически активным добавкам. Расчетным путем показано, что для создания функциональных пищевых продуктов на рыбной основе из рыб семейства лососевых достаточно введения 4 г полученной биологически активной добавки на 100 г продукта. Также наблюдается улучшение органолептических свойств пищевых продуктов из нежирных видов рыб. Показано, что для удовлетворения 30% от рекомендуемой суточной нормы потребления омега-3-кислот, при разработке функциональных пищевых продуктов на основе форели радужной и сельди атлантической, необходимо ввести 1,98 г и 1,8 г криоконцентрированного рыбьего жира. После инкапсулирования в нанокапсулы препарат станет пригодным для обогащения омега-3-кислотами любых пищевых продуктов, что является предметом дальнейших исследований.</p></trans-abstract><kwd-group xml:lang="en"><kwd>biologically active food additives</kwd><kwd>hydrolyzate</kwd><kwd>fish oil</kwd><kwd>cryoconcentration</kwd><kwd>omega-3-fatty acids</kwd><kwd>omega-6-fatty acids</kwd><kwd>fish waste</kwd><kwd>functional food</kwd><kwd>extraction</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>биологически активные пищевые добавки</kwd><kwd>гидролизат</kwd><kwd>рыбий жир</kwd><kwd>криоконцентрирование</kwd><kwd>омега-3-жирные кислоты</kwd><kwd>омега-6-жирные кислоты</kwd><kwd>рыбные отходы</kwd><kwd>функциональные продукты питания</kwd><kwd>экстрагирование</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Ryckebosch E, Bruneel C, Muylaert K, &amp; Foubert I. 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