Bulletin of the Russian Military Medical AcademyBulletin of the Russian Military Medical Academy1682-73922687-1424Eco-Vector6364810.17816/brmma63648Review ArticleThe need to create and implement a platform for managing the professioyal reliability of military personnel of the armed forces of the russian federation, based on the principles of personalizet medicineKutelevGennadiy G.<p>candidate of medical sciences, doctoral student</p>gena08@yandex.ruCherkashinDmitry V.<p>doctor of medical sciences, professor</p>cherkashin_dmitr@mail.ruTrishkinTrishkin V.<p>candidate of medical sciences</p>moro5555@yandex.ruKryukovEvgeny V.<p>doctor of medical sciences, professor</p>evgeniy.md@mail.ruFisunAlexander Y.<p>doctor of medical sciences, professor</p>a_fisun@list.ruMarchenkoMarchenko A.<p>doctor of medical sciences, professor</p>andrew.marchenko@mail.ruShuleninKonstantin S.<p>doctor of medical sciences, the associate professor</p>shulenink@mail.ruKrivoruchkoAlexander B.<p>candidate of medical sciences, associate professor</p>krab25@mail.ruSobolevAlexey D.<p>adjunct</p>sobolevvmeda@rambler.ruMilitary Medical Academy named after S.M. KirovMain Military Medical Directorate of the Ministry of Defence of the Russian FederationERA Military Innovative Technopolis120520212311771861803202118032021Copyright © 2021, Kutelev G.G., Cherkashin D.V., Trishkin T.V., Kryukov E.V., Fisun A.Y., Marchenko M.A., Shulenin K.S., Krivoruchko A.B., Sobolev A.D.2021<p>The article analyzes modern federal programs aimed at preserving the health and well-being of the population and creating a comfortable and safe environment for life and work. The article describes the arsenal of strategic directions for assessing the risk of developing diseases, diagnostic approaches and scientific principles that contribute to the successful implementation of evaluation measures. The possibility of clarifying the cardiovascular risk in the study of the role of military-professional factors in the formation of cardiovascular pathology in military personnel of the Armed Forces of the Russian Federation is discussed. The article analyzes the effectiveness of traditional diagnostic methods used by the medical service, as well as ways to improve this efficiency when using molecular genetic studies to search for associations with risk factors for neuropsychic and cardiovascular pathology. The article considers the practical necessity of creating a professional reliability management platform based on the principles of personalized medicine, which contributes to prolonging professional longevity and improving the combat readiness of servicemen of the Armed Forces of the Russian Federation. Such a method of implementing the professional reliability management platform will significantly increase the informativeness of traditional methods of early diagnosis of cardiovascular and neuropsychic pathology.</p>professional reliabilitypersonalized medicineprofessional longevityrisk factors for the development of cardiovascular diseasesstressprevention of non-communicable diseaseshigh-tech healthcaremolecular genetic studiesпрофессиональная надежностьперсонализированная медицинапрофессиональное долголетиефакторы риска развития сердечно-сосудистых заболеванийстресспрофилактика неинфекционных заболеванийвысокотехнологичное здравоохранениемолекулярно-генетические исследования[Talashmanova K. On the problem of understanding the professional reliability of the subject. Human capital. 2020;3(135):239–245. (In Russ.)][Interstate standard GOST R 27.002-89 Reliability in technology. Basic concepts. Industrial product dependability. General concepts. Terms and definitions. Moscow; 1989. 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