Modification of the functional and metabolic status of erythrocytes in the patients presenting with chronic periodontitis


Certain pharmacological effects of cytoflavin were investigated in the patients presenting with chronic generalized periodontitis. The inclusion of this agent in the combined treatment of the disease leads to a decrease of the severity of the inflammatory process in the periodontal tissues. This effect of cytoflavin is to a large extent attributable to its ability to modulate the functional and metabolic state of erythrocytes. It was shown that cytoflavin promotes restoration of the phospholipid bilayer of the erythrocyte membrane due to the reduction of phospholipase A2 activity. Moreover, the product eliminates effects of oxidative stress.


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