All-new bactericidal solutions to be used in dentistry, maxillofacial surgery, urology, obstetrics, gynaecology, ENT, proctology have been developed. By means of electric impulse and disperse condensate means, water and alcoholic (ethanolic) colloidal nanodispersed systems of metals have been procured and also their oxides based on: argentum (Ag), titanium dioxide (TiO), ferrous oxide (FeO), tantalum oxide (TaO), vanadium oxide (VO2), cobaltous oxide (CoO), tantalum dioxide TaO2, zink oxide (ZnO), cupric oxide (CuO), a mixed solution of: titanium dioxide (TiO), aluminium oxide (Al2O) and molybdenum dioxide (MoO). The research has been made on culture of dentobacterial plaque and mixed culture, issued from gingival spaces. The composition of culture was identified with S. aureus, S. epidermidis and nonfermentable kinds of E. coli. The observation period lasted more than nineteen days. All solutions showed highly prolonged bactericidal activity in dilutions from the whole solution 1-20 mg/L. Dilution step is tenfold (10-1; 10-2; IO-'; 10-4; 10-5; 10-6; 10-7). The bactericidal activity ofpowder specimen of glass, used to produce dental filling material and disintegrates of composite materials, issued by «StomaDent» CJSC, processed by Ag and FeO2 nanoparticles, have been studied. Tested materials have long, up to 19 days and more, bactericidal activity.

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About the authors

V. K Leont'ev

Russian Academy of Sciences

119991, Moscow

D. V Kuznetsov

National research technological University «MISIS»

119049, Moscow

G. A Frolov

National research technological University «MISIS»

119049, Moscow

I. P Pogorelskiy

Vyatka state University

610000, Kirov

N. V Latuta

«I.M. Sechenov First Moscow state medical University» Ministry of health of Russia (Sechenovskiy University)

119991, Moscow, Russia

Yakov Nikolaevich Krasenkov


Russia, 117342, Moscow
Cand. Med. Sci, senior specialist of the clinic ROSDENT


  1. Бондаренко В.М., Чубунов В.Ф., Бондаренко В.М. Микроэлементы и инфекция. Журн. микробиол. 1987; 3: 118-26.
  2. Погорельский И.П., Фролов Г.А., Гурин К.И. Микробиологические аспекты отбора наночастиц металлов для создания на их основе антимикробных дезинфицирующих композиций. Дезинфекционное дело. 2012; 4: 37-40.
  3. Погорельский И.П., Фролов Г.А., Гурин К.И. Сочетанное действие наночастиц серебра и перекиси водорода на жизнеспособность и ультраструктуру клеток Bacillus cereus. Дезинфекционное дело, 2014; 2: 35-7.
  4. Поляков В.А., Бурачевский И.И., Морозова С.С., Фролов Г.А., Карасенков Я.Н., Дмитриева Е.В., Доманская Д.С. Новые аспекты «серебряной» фильтрации водок. Пищевая промышленность. 2013; 2: 24-7.
  5. Современная стоматология - эффективность профилактики и лечения. Нанотехнологии в стоматологии: материалы Всероссийской научно-практической конференции с международным участием, посвященной 60-летию деятельности стоматологического факультета Тверской государственной медицинской академии на Тверской земле / Под ред. М.Н. Калинкина, В.А. Румянцева, И.А. Жмакина, Б.Н. Давыдова, К.Б. Баканова, В.В. Тетарчука, А.А. Артамонова. Тверь; 2014: 175-7.
  6. Яковлева Г.В., Стехин А.А. Особенности токсических свойств нанообъектов. Гигиена и санитария. 2008; 6: 21-6.
  7. Denyer S.P., Stewart G.S.A.B. Mechanism of action disinfectants. Intern. Biodeteriorat. Biodegradat. 1998; 41: 261-8.
  8. Fan W., Wu D., Tay F.R. Effects of adsorbed and template nanosilver in mesoporus calcium-silicate nanoparticles on inhibition of bacteria colonization of dentin. Int. J. Nanomed. 2014; 12: 217-30.
  9. Vargas-Reus M.A., Memarzadeh K., Huang J. Antimicrobial activity of nanoparticulate metal oxides against peri-implantitis pathogens. Int. J. Antimicrobial. Agents. 2012; 40: 135-9.
  10. Zhang K., Li F., Imarato S. Dual antibacterial agents of nanosilver and 12-methacryloyloxydodecylpyridinium bromide in dental adhesive to inhibit caries. J. Biomed. Mater. Res. B Appl. Biomater. 2013; 101: 929-38.



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