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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Urologiia</journal-id><journal-title-group><journal-title xml:lang="en">Urologiia</journal-title><trans-title-group xml:lang="ru"><trans-title>Урология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1728-2985</issn><issn publication-format="electronic">2414-9020</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">281095</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Clinico-morphological features of female urethral meatus polyps</article-title><trans-title-group xml:lang="ru"><trans-title>Клиникоморфологические особенности полипов наружного отверстия уретры у женщин</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nejmark</surname><given-names>A. I</given-names></name><name xml:lang="ru"><surname>Неймарк</surname><given-names>А. И</given-names></name></name-alternatives><bio xml:lang="en"><p>Department of Urology and Nephrology</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, заведующий кафедрой урологии и нефрологии</p></bio><email>urologagmu@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Jakovlev</surname><given-names>A. V</given-names></name><name xml:lang="ru"><surname>Яковлев</surname><given-names>А. В</given-names></name></name-alternatives><bio xml:lang="en"><p>Department of Urology and Nephrology</p></bio><bio xml:lang="ru"><p>кафедра урологии и нефрологии</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nepomnjashhih</surname><given-names>L. M</given-names></name><name xml:lang="ru"><surname>Непомнящих</surname><given-names>Л. М</given-names></name></name-alternatives><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Altai State Medical University of Minzdrav of Russia</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО «Алтайский государственный медицинский университет» МЗ РФ</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Institute of Pathology and Pathomorphology</institution></aff><aff><institution xml:lang="ru">ФГБНУ «Институт молекулярной патологии и патоморфологии»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2015-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2015</year></pub-date><issue>3</issue><issue-title xml:lang="en">NO3 (2015)</issue-title><issue-title xml:lang="ru">№3 (2015)</issue-title><fpage>33</fpage><lpage>38</lpage><history><date date-type="received" iso-8601-date="2023-02-25"><day>25</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2015, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2015, ООО «Бионика Медиа»</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/1728-2985/article/view/281095">https://journals.eco-vector.com/1728-2985/article/view/281095</self-uri><abstract xml:lang="en"><p>The aim of the study was to establish the clinical and morphological characteristics offemale urethral polyps including cases with concomitant sexually transmitted infections. A total of 150 women were enrolled in the study. The evaluation of microcirculatory changes, morphological parameters and immunogram indices of urethral polyps were carried out. The most common infectious agent in patients with urethral polyps was Ureaplasma urealyticum. In those cases predominance of inflammatory symptoms and elevated levels of serum proinflammatory cytokines were identified. It is found that the pronounced inflammatory reaction leads to an increase in the relative area of the subepithelial microvascular bed and the cellular elements population of lamina mucosa propria, as well as to the relative predominance of congestive forms of microcirculation disturbances according to the laser Doppler flowmetry.</p></abstract><trans-abstract xml:lang="ru"><p>Целью исследования было установить клинико-морфологические особенности полипов уретры у женщин, в том числе на фоне инфекции, передаваемой половым путем. Обследованы 150 женщин. Проведена оценка микроциркуляторных изменений в полипах уретры, показателей иммунограммы и морфологических данных удаленных полипов. Наиболее распространенным инфекционным агентом у пациенток с полипами уретры оказалась Ureaplasma urealyticum. При этом доминировали симптомы воспалительного характера, наблюдалось повышение уровня провоспалительных цитокинов в сыворотке крови. Установлено, что выраженная воспалительная реакция приводит к увеличению относительной площади субэпителиального микрососудистого русла и клеточных элементов собственной пластинки слизистой оболочки, а также к относительному преобладанию гиперемической формы расстройств микроциркуляции, согласно данным лазерной допплеровской флоуметрии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>urethral polyp</kwd><kwd>microcirculation in polyps</kwd><kwd>sexually transmitted infection</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>полип уретры</kwd><kwd>микроциркуляция в полипах</kwd><kwd>инфекция</kwd><kwd>передаваемая половым путем</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Кан Д.В. Руководство по акушерской и гинекологической урологии. М.: Медицина, 1986. 487 с.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Kimura T., Miyazato M., Kawai S., Hokama S., Sugaya K., Ogawa Y. 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