UrologiiaUrologiiaУрология1728-29852414-9020Bionika Media29643710.18565/urology.2018.6.131-138ArticlesСтатьиReview ArticleRecurrence prevention for urinary stone disease. Part II. The factors associated with increase in incidence of urinary stone disease. Current views on the mechanisms of stone formation (continuation)Метафилактика мочекаменной болезни. Часть 2. Факторы роста заболеваемости МКБ. Современный взгляд на механизмы камнеобразования (продолжение)SaenkoV. SСаенкоВ. С

Dr.Med.Sci. professor at the Department of Urology

д.м.н., профессор кафедры урологии

saenko_vs@mail.ruGazimievM. AГазимиевМ. А

professor at the Department of Urology

д.м.н., профессор кафедры урологии

PesegovS. VПесеговС. В

Ph.D., urologist at the Department of Extracorporeal Shock-wave lithotripsy of UKB №2

к.м.н., врач-уролог УКБ № 2

AlyaevYu. GАляевЮ. Г

corresponding member ofRAS, Dr.Med.Sci., professor

член-корр. РАН, д.м.н., профессор

FGAOU VO I.M. Sechenov First Moscow State Medical UniversityФГАОУ ВО «Первый МГМУ им. И. М. Сеченова» Сеченовский Университет151220186NO6 (2018)№6 (2018)13113827022023Copyright ©; 2018, Bionika MediaCopyright ©; 2018, ООО «Бионика Медиа»2018Bionika MediaООО «Бионика Медиа»https://journals.eco-vector.com/1728-2985/article/view/296437

Urinary stone disease is one of the most actively progressing diseases, which are associated with metabolic disturbances and are influenced by the genetic, environmental factors and lifestyle \. In the article the current views on initiation factors of stone formation and theories of stone formation are reviewed. The factors that play an important role in the activation and inhibition of nucleation and aggregation of stone -forming substances are discussed. All theories of stone formation are based on the common condition, which is the supersaturation of stone-forming elements. The microelements involved in the stone formation, the most common metabolic disorders and their role in stone formation are discussed.

Мочекаменная болезнь - одно из наиболее активно прогрессирующих заболеваний, являющихся болезнью обмена веществ на фоне воздействия генетических, экологических факторов и образа жизни. В статье представлены современные взгляды на факторы инициации образования камней и теории камнеобразования. Обсуждены факторы, играющие важную роль в активации и ингибировании процессов нуклеации и агрегации камнеобразующих веществ. Все теории камнеобразования объединены основным условием - наличием пересыщения мочи камнеобразующими минералами. Описаны микроэлементы, участвующие в формировании мочевых камней, наиболее часто встречающиеся метаболические нарушения и их роль в камнеобразовании.

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