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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Urologiia</journal-id><journal-title-group><journal-title xml:lang="en">Urologiia</journal-title><trans-title-group xml:lang="ru"><trans-title>Урология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1728-2985</issn><issn publication-format="electronic">2414-9020</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">680275</article-id><article-id pub-id-type="doi">10.18565/urology.2024.6.53-60</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Sexual constitution (sexuality) of men with prostate cancer</article-title><trans-title-group xml:lang="ru"><trans-title>Половая конституция (сексуальность) мужчин с раком предстательной железы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kogan</surname><given-names>M. I.</given-names></name><name xml:lang="ru"><surname>Коган</surname><given-names>М. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Ph.D., MD, professor, Honored Scientist of Russia, Head of the Department of Urology and Human Reproductive Health with the course of pediatric urology and andrology</p></bio><bio xml:lang="ru"><p>заслуженный деятель науки РФ, доктор медицинских наук, профессор, заведующий кафедрой урологии</p></bio><email>dept_kogan@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Efremov</surname><given-names>M. E.</given-names></name><name xml:lang="ru"><surname>Ефремов</surname><given-names>М. Е.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Ph.D., assistant at the Department of Urology, urologist</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук, ассистент кафедры урологии, врач-уролог</p></bio><email>efremov.uro@yandex.ru</email><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Medvedev</surname><given-names>V. L.</given-names></name><name xml:lang="ru"><surname>Медведев</surname><given-names>В. Л.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Ph.D., MD, professor, Head of the Department of Urology, Deputy Chief on Urology and Chief of the Uronephrologic center</p></bio><bio xml:lang="ru"><p>доктор медицинских наук, профессор, заведующий кафедрой урологии, заместитель главного врача</p></bio><email>medvedev_vl@mail.ru</email><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Anosov</surname><given-names>A. D.</given-names></name><name xml:lang="ru"><surname>Аносов</surname><given-names>А. Д.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>senior laboratory assistant, urologist</p></bio><bio xml:lang="ru"><p>старший лаборант кафедры, врач-уролог</p></bio><email>vester.orient@gmail.com</email><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bratova</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Братова</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Head of the Clinical and Diagnostic Laboratory</p></bio><bio xml:lang="ru"><p>зав. клинико-диагностической лабораторией</p></bio><email>dept_kogan@mail.ru</email><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">FGBOU VO Rostov State Medical University of the Ministry of Health of the Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Ростовский государственный медицинский университет» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">FGBOU VO Kuban State Medical University of Minzdrav of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Кубанский государственный медицинский университет» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">GBUZ Scientific and Research Institute of Regional Clinical Hospital №1 named after prof. S.V. Ochapovsky</institution></aff><aff><institution xml:lang="ru">ГБУЗ НИИ Краевая клиническая больница № 1 им. проф. Очаповского</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-12-10" publication-format="electronic"><day>10</day><month>12</month><year>2024</year></pub-date><issue>6</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>52</fpage><lpage>59</lpage><history><date date-type="received" iso-8601-date="2025-05-23"><day>23</day><month>05</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-05-23"><day>23</day><month>05</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, ООО «Бионика Медиа»</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/1728-2985/article/view/680275">https://journals.eco-vector.com/1728-2985/article/view/680275</self-uri><abstract xml:lang="en"><p><bold>Introduction</bold><bold>. </bold>Evaluation of sexual function in men with prostate cancer (PCa) is of great importance, since treatment methods can influence on sexual function. Questionnaires allow to evaluate sexual function in men during the last month before the treatment. At the same time, the sexual life of a man who has developed PCa is still not studied. The experience of assessing the sexual constitution of men with newly diagnosed PCa is presented in the article.</p> <p><bold>Aim</bold><bold>.</bold> To determine male sexuality from its first manifestations to the moment of PCa diagnosis, i.e. throughout the entire period of sexual activity, as well as to evaluate the relationship between sexuality and serum testosterone levels at the time of PCa diagnosis.</p> <p><bold>Materials</bold><bold> </bold><bold>and</bold><bold> </bold><bold>methods</bold><bold>.</bold> A total of 87 patients aged 47–75 years diagnosed with PCa pf T1C-3bN0-1M0-1a, who independently answered the questions of the questionnaire "Integral assessment of male sexuality" (2009), were included in the study. All men underwent an examination for serum total testosterone.</p> <p><bold>Results</bold><bold>.</bold> From the whole cohort, 90.8% of men were defined as hyposexual, and 9.2% had normal sexuality. Weak sexual constitution was found throughout the entire period of sexual life, but by the time of PCa diagnosis, it was even lower. 70.1% of patients had a total testosterone deficiency at the time of PCa detection. No reliable relationship was found between the reduced and normal sexual constitution and serum testosterone levels.</p> <p><bold>Conclusion</bold><bold>.</bold> Most men with PCa have low sexual activity throughout their lives, a high incidence of testosterone deficiency at the time of cancer diagnosis. In addition, there is no relationship between serum testosterone levels and male sexuality.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Введение.</bold> Оценке сексуальной функции мужчин с раком предстательной железы придается важное значение, так как методы лечения рака простаты способны повреждать сексуальную функцию, причем опросники сексуальной функции у мужчин определяют ее состояние на протяжении последнего месяца перед началом лечения. В то же время, половая жизнь мужчины, у которого развился рак простаты, до настоящего времени остается не исследованной. В настоящей статье представлен опыт оценки половой конституции мужчин с впервые диагностированным раком предстательной железы.</p> <p><bold>Цель.</bold> Определение сексуальности мужчин от ее первых проявлений до момента диагностики рака простаты, т.е. на протяжении всего периода половой активности, а также определение связи сексуальности с уровнем тестостерона крови на момент диагностики рака простаты.</p> <p><bold>Материалы и методы.</bold> В исследование включены 87 пациентов в возрасте 47–75 лет с диагнозом рак предстательной железы T1С-3вN0-1M0-1а, которые самостоятельно ответили на вопросы опросника «Интегральная оценка сексуальности мужчин» (2009 г.) Всем пациентам проведено исследование сыворотки крови на содержание общего тестостерона.</p> <p><bold>Результаты.</bold> 90,8 % мужчин когорты определены как гипосексуальные, а 9,2% – как нормосексуальные. Показатели слабой половой конституции отмечены на протяжении всего периода сексуальных отношений, но к моменту диагностики рака простаты показатели сексуальности оказались еще более сниженными. 70,1% пациентов имели дефицит общего тестостерона на момент выявления рака простаты. Обнаружено отсутствие достоверной взаимосвязи параметров сниженной и нормальной половой конституции с уровнями сывороточного тестостерона у обследованных больных.</p> <p><bold>Заключение.</bold> Большинство мужчин с раком предстательной железы характеризуются низкой сексуальной активностью на протяжении всей жизни, высокой частотой дефицита тестостерона на момент диагностики рака и отсутствием взаимосвязи уровней тестостерона с сексуальностью мужчин.</p></trans-abstract><kwd-group xml:lang="en"><kwd>male sexual constitution</kwd><kwd>male sexuality</kwd><kwd>prostate cancer</kwd><kwd>serum testosterone</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>половая конституция мужчин</kwd><kwd>сексуальность мужчин</kwd><kwd>рак предстательной железы</kwd><kwd>тестостерон крови</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Somov A.N., Suslin S.A. Prostate cancer. Epidemiology, risk factors and early detection. 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