Viagra effects on polysystemic energy metabolism in stress (an experimental study)
- Authors: Vishnevsky EL1, Sukhorukov VS1, Pushkar DY.1, Shabelnikova EI1, Vishnevsky AE1, Koval AN1
-
Affiliations:
- Issue: No 4 (2004)
- Pages: 51-55
- Section: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/275334
- ID: 275334
Cite item
Full Text
Abstract
(doxasozine) and viagra on polysystemic energy metabolism in
stress. All the animals were examined for cytochemical activity ofsuccinate
dehydrogenase, lactate dehydrogenase in blood lymphocytes,
antioxidant activity of blood plasm, levels of hydroperoxides, malonic
dialdehyde. 3-hour immobilization raises functional activity of mitochondria
manifesting with intensification of energy metabolism.
Adrenoreceptors blockade by Cardura prevents changes in the ceUular
metabolism. The same antistress effect is observed in viagra action.
This newly discovered mechanism may prevent complications of
adrenergic reactions accompanying sexual intercourse..
About the authors
E L Vishnevsky
V S Sukhorukov
D Yu Pushkar
E I Shabelnikova
A E Vishnevsky
A N Koval
References
- Кротовский Г. С., Зудин А. М. Виагра - 5 лет успеха. М.; 2003.
- Fedotcheva N. I., Leont'ev D. S., Kondrashova M. N. Reciprocal effect of adrenaline and serotonin on oxidation of succinate and ctketoglutarate in rat liver and brain homogenates. Mitochondrion 2002; 1 (6): 519-520.
- Kondrashova M. N., Doliba N. M. Polarographic observation of substrate-level phosphorylation and its stimulation by acetylcholine. FEBS Lett. 1989; 243 (2): 153-155.
- Меерсон Ф.З., Пшенникова М. Г. Адаптация к стрессорным ситуациям и физическим нагрузкам. М.; 1988.
- Селье Г. Очерки об адаптационном синдроме: Пер. с англ. М.; 1960.
- Подсеваткин В. Г., Комков А. П., Подсеваткин Д. В. и др. Сравнительное исследование стресс-протекторной активности гипербарической оксигенации и диазепама. В кн.: Материалы VI Международной междисциплинарной региональной конф. по биологической психиатрии "Стресс и поведение". М.; 2001. 25-26.
Supplementary files
