Vliyanie indol-3-karbinola i epigallokatekhin-3-gallata na protsessy al'teratsii i reparatsii v uretre v eksperimente


Cite item

Full Text

Abstract

The effects of indol-3-carbinol and epigallocatexin-3-gallate on alteration and reparation in the urethra were studied in 30 male Shinshilla rabbits. From the observation day 2 the rabbits were fed with indol-3-carbinol and epigallocatexin-3-gallate in addition to standard diet. Microcirculation was assessed with a laser analyzer of capillary circulation LAKK-01 which detected earlier recovery of microcirculation in the group of the animals fed with indol-3-carbinol and epigallocatexin-3-gallate. Thus, antioxidant and antiproliferative properties of indol-3-carbinol and epigallocatexin-3-gallate improve alteration and reparation in affected urethra due to development of soft elastic connective tissue with better capillary circulation.

References

  1. Koraitim M. Experience with 170 cases of posterior urethral strictures during 7 years. J. Urol. (Baltimore) 1985; 133 (3): 408-410.
  2. Ruutu M., Alffhan O., Standertsjold-Nordenstam C. et al. Treatment of urethral stricture by uretroplasty or direct vision uretrothomy. Scand. J. Urol. Nephrol. 1983; 17 (1): 1-4.
  3. Красулин В. В., Серебренников С. М., Жульнев А. П., Панченко С. Н. Способ соединения концов резецированной уретры. Урол. и нефрол. 1990; 4: 54-57.
  4. Русаков В. И. Хирургическое лечение стриктур уретры (экспериментально-клиническое исследование): Автореф. дис. ... д-ра мед. наук. Ростов-н/Д, 1960.
  5. Гнилорыбов В. Г. Хирургическое лечение посттравматических стриктур уретры: Автореф. дис. ... канд. мед. наук. М.; 1989.
  6. Klein H. J., Scheter M. Adischtung von Blutungen Fibrinkleber in der Neurochinirgia. Die velten Hefle. 1983. 155-159.
  7. Коган М. И. Современные методы лечения стриктуры уретры. В кн.: Материалы пленума правления Российского о-ва урологов. Екатеринбург; 2006. 271-281.
  8. Yoho A. V., Drach G. Experimental evaluation of tissue adhesives in urogenital surgery. J. Urol. (Baltimore) 1964; 92: 56-59.
  9. Marcovich R., Williams A. L. et al. Comparison of 2-octyl cyanoacrylate adhesive, fibrin glue, end suturing for wound closure in the porcine urinary tract. Urology 2001; 57: 806-810.
  10. Лоран О. Б., Велиев Е. И. Открытая хирургическая техника в лечении стриктур уретры. В кн.: Материалы пленума правления Российского о-ва урологов. Екатеринбург; 2006. 281-287.
  11. Bonner R. F., Nossal R. Modal for laser doppler measurments of blood flow in tissue microcirculation. Appl. Optics. 1981; 20: 2097.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2009 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies