Comparative analysis of the influence of HPV in mono and mixed variants on ejaculate parameters

Мұқаба

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

Introduction. The problem of male infertility is multifactorial. However, in recent years, the involvement of viruses, in particular human papillomaviruses (HPV), in the development of this condition has been actively discussed.

Purpose of the study: to study the effect of HPV in mono and mixed versions on ejaculate parameters.

Materials and methods. We analyzed the results of a survey of 105 patients aged from 22 to 40 years (average age – 32.3±6.4) with a diagnosis of infertility and pathospermia combined with PVI, with the absence of other risk factors.

Results. The presence of several viruses in the ejaculate increased the degree of biochemical and cytopathomorphological disorders of sperm recorded in patients with HPV-associated infertility.

Conclusions. a combination of several types of virus leads to a deterioration in the functional activity of Leydig and Sertoli cells of the testicles, characterized by a decrease in the synthesis of total testosterone levels and the development of qualitative and quantitative disorders of the ejaculate. This circumstance is due to the fact that with the association of several microorganisms, there is most likely an increase in the pathogenic potential of HPV.

Негізгі сөздер

Толық мәтін

Рұқсат жабық

Авторлар туралы

G. Magomedov

Rostov State Medical University, Ministry of Health of the Russian Federation

Email: magomed544@mail.ru
ORCID iD: 0000-0003-4859-5085

postgraduate student of the Department of Urology and Human Reproductive Health (with a course of Pediatric Urology-Andrology) 

Ресей, Rostov-on-Don

M. Kogan

Rostov State Medical University, Ministry of Health of the Russian Federation

Email: dept_kogan@mail.ru
ORCID iD: 0000-0002-1710-0169

Honored Scientist of the Russian Federation, Doctor of Medical Sciences, Professor; Head of the Department of Urology and Human Reproductive Health with the course of pediatric urology and andrology

Ресей, Rostov-on-Don

D. Sizyakin

Rostov State Medical University, Ministry of Health of the Russian Federation

Email: dsiziakin@mail.ru
ORCID iD: 0000-0002-9627-2582

M.D., Dr.Sc. (Med), Full Prof.; Prof., Dept. of Urology and Human Reproductive Health (with the Pediatric Urology and Andrology course)

Ресей, Rostov-on-Don

Kh. Ibishev

Rostov State Medical University, Ministry of Health of the Russian Federation

Хат алмасуға жауапты Автор.
Email: Ibishev22@mail.ru
ORCID iD: 0000-0002-2954-842X

Doctor of Medical Sciences, Professor of the Department of Urology and Human Reproductive Health (with a course of pediatric urology and andrology)

Ресей, Rostov-on-Don

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Әрекет
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2. Fig. 1. Correlation between the number of virus types and the Tc equation in blood serum

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3. Fig. 2. Correlation between the number of virus types and ejaculate volume

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4. Fig. 3. Correlation between the number of virus types and the total number of spermatozoa in the ejaculate

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5. Fig. 4. Correlation between the number of virus types and the number of spermatozoa in 1 ml of ejaculate

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6. Fig. 5. Correlation between the number of virus types and the overall motility of spermatozoa in the ejaculate

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7. Fig. 6. Correlation between the number of virus types and progressive sperm motility in the ejaculate

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8. Fig. 7. Correlation between the number of virus types and the number of spermatozoa with normal morphology

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9. Fig. 8. Correlation between the number of virus types and the level of citric acid in the ejaculate

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