Non-Neoplastic Kidney Pathology in Specimens after Tumor-Related Nephrectomy
- Autores: Gasanov A1, Musaev D1
-
Afiliações:
- Azerbaijan Medical University
- Edição: Nº 4 (2015)
- Páginas: 52-54
- Seção: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/281715
- ID: 281715
Citar
Texto integral
Acesso aberto
Acesso está concedido
Acesso é pago ou somente para assinantes
Resumo
The aim of the study was to determine the incidence of pathological changes in the unaffected parts of tumor-related nephrectomy specimens. Tissue samples obtained from 507 patients were analyzed. Non-neoplastic pathology in the tumor-free kidney tissue along with the tumor was detected in 63 (12.42%) cases. All non-tumor diseases co-existing with tumors were found in patients of older age groups. Approximately 1/3 of the non-neoplastic pathology was nephrosclerosis lesions (30.16%), and in half of those cases (52.63%) transitional cell carcinoma was detected. It is pointed out that for the detection of glomerular lesions careful microscopic examination of the unaffected parts of renal parenchyma is needed. The examination, carried out by means of special staining techniques (histochemistry, immunohistochemistry, immunofluorescence), electron microscopy, and with the involvement of nephropathologists, can improve glomerular pathology detection rate after nephrectomy.
Palavras-chave
Sobre autores
A Gasanov
Azerbaijan Medical UniversityAzerbaijan Medical University
D Musaev
Azerbaijan Medical UniversityAzerbaijan Medical University
Bibliografia
- Eble J.N., Togashi K, Pisani P. Renal cell carcinoma. In: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. Eble J.N., Sauter G., Epstein J.I., Sesterhenn I.A., eds. Lyon: IARC Press, 2004. P. 12-14.
- Henriksen K.J., Meehan S.M., Chang A. Non-neoplastic renal diseases are often unrecognized in adult tumor nephrectomy specimens: a review of 246 cases. Am. J. Surg. Pathol. 2007;31(11):1703-1708. 3.
- Ahmed M, Solangi K., Abbi R, Adler S. Nephrotic syndrome, renal failure, and renal malignancy: an unusual tumor-associated glomerulonephritis. J. Am. Soc. Nephrol. 1997;8(5):848-852.
- Bijol V., Mendez G.P., Hurwitz S., Rennke H.G., Nose V. Evaluation of the nonneoplastic pathology in tumor nephrectomy specimens: predicting the risk of progressive renal failure. Am. J. Surg. Pathol. 2006;30(5):575-584.
- Garcia-Roig M., Gorin M.A., Parra-Herran C., Garcia-Buitrago M., Kava B.R., Jorda M., Soloway M.S., Manoharan M., Ciancio G. Pathologic evaluation of non-neoplastic renal parenchyma in partial nephrectomy specimens. World J. Urol. 2013;31(4):835-839.
- Gautam G., Lifshitz D., Shikanov S., Moore J.M., Eggener S.E., Shalhav A.L., Chang A. Histopathological predictors of renal function decrease after laparoscopic radical nephrectomy. J. Urol. 2010;184(5):1872-1876.
- Sarsik B., Simsir A., Yilmaz M., Yorukoglu K., Sen S. Spectrum of nontumoral renal pathologies in tumor nephrectomies: nontumoral renal parenchyma changes. Ann. Diagn. Pathol. 2013;17(2):176- 182.
- Henriksen K.J., Meehan S.M., Chang A. Nonneoplastic kidney diseases in adult tumor nephrectomy and nephroureterectomy specimens: common, harmful, yet underappreciated. Arch. Pathol. Lab. Med. 2009;133(7):1012-1025.
- Varshavskii V.A., Proskurneva E.P., Gasanov A.B., Severgina L.O., Shestakova L.A. Subdivision of certain morphological variants of chronic glomerulonephritis. Arkh. Patol. 1999;61(5):40-46.
Arquivos suplementares
