SOLIFENACIN IN THE TREATMENT OF OVERACTIVE BLADDER: RESULTS OF A RANDOMIZED DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY


如何引用文章

全文:

开放存取 开放存取
受限制的访问 ##reader.subscriptionAccessGranted##
受限制的访问 订阅或者付费存取

详细

The article presents the results of the evaluation of clinical efficacy and safety of the M-cholinoblocker solifenacin in the treatment of symptoms of overactive bladder (OAB). The study included 24 women aged from 47 to 69 years with symptoms of OAB lasting more than 3 months. It is shown that solifenacin at a dose of 5 mg reduces the quality of urinary urgency, improves the condition according to assessment of degree of discomfort due to symptoms of the OAB, treatment satisfaction and condition of the bladder.

全文:

受限制的访问

参考

  1. Abrams P., Cardozo L., Fall M. et al. The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society. Neurourol Urodyn 2002; 21:167-78.
  2. Abrams P., Artibani W., Cardozo L., Dmochowski R., van Kerrebroeck P., Sand P. Reviewing the ICS 2002 terminology report: the ongoing debate. Neurourol Urodyn 2006; 25:293-94.
  3. Payne C. K., Kelleher C. Redefining response in overactive bladder syndrome. BJU Int 2007; 99:101-6.
  4. Lesch K. P., Merschdorf U. Impulsivity, aggression, and serotonin: a molecular psychobiological perspective. Behav Sci Law 2000; 18:581-604.
  5. Steers W. Overactive bladder (OAB): What we thought we knew and what we know today. Urol Suppl 2002; 1:3-10.
  6. Artibani W. Outcomes in overactive bladder treatment: patient perception - a key to success. Eur Urol Suppl 2007; 6:17-22.
  7. Schagen van Leeuwen J. H., Castro R., Busse M., Bemelmans B. L. The placebo effect in the pharmacologic treatment of patients with lower urinary tract symptoms. Eur Urol 2006; 50:440-52.
  8. Chapple C. R., Artibani W., Cardozo L. D. et al. The role of urinary urgency and its measurement in the overactive bladder symptom syndrome: current concepts and future prospects. BJU Int 2005; 95:335-40.
  9. Chapple C. R., Martinez-Garcia R., Selvaggi L. et al. A comparison of the efficacy and tolerability of solifenacin succinate and extended release tolterodine at treating overactive bladder syndrome: results of the STAR trial. Eur Urol 2005; 48:464-70.

补充文件

附件文件
动作
1. JATS XML

版权所有 © Bionika Media, 2012