Extracorporeal photochemotherapy as prevention of graft rejection, coupled with declining infectious complications rates in urological patients


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This study presents results of extracorporeal photochemotherapy (EPCT) application in 24 renal allograft recipients (RAR), who suffered chronic kidney disease (CKD) caused by urological diseases. The comparison group treated only with chemical immunosuppression comprised 24 recipients who received transplants from the same donors as intervention group patients. It was found that EPCT reduces not only the number of RAR rejections, but also the incidence of infectious complications. The effectiveness of EFHT was confirmed by clinical, laboratory and immunological data, and by protocol biopsy results. Possible mechanisms of preservation of anti-infectious protection in the setting of chemical immunosuppression when using EPCT are discussed.

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作者简介

V. Fedulkina

MRRCI n.a. M.F. Vladimirskiy

Email: v.fedulkina@mail.ru
Ph.D., Senior Researcher at Surgical at Department of Transplantation and Dialysis

A. Vatazin

MRRCI n.a. M.F. Vladimirskiy

Department of Transplantation, Nephrology and Surgical Hemocorrection

A. Kil'dyushevskiy

MRRCI n.a. M.F. Vladimirskiy

Department of Transplantation, Nephrology and Surgical Hemocorrection

A. Zul'karnaev

MRRCI n.a. M.F. Vladimirskiy

Department of Transplantation, Nephrology and Surgical Hemocorrection

R. Kantariya

MRRCI n.a. M.F. Vladimirskiy

Department of Transplantation, Nephrology and Surgical Hemocorrection

参考

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