Features of refractogenesis in infants with retinopathy of prematurity during initial years of life


The article presents the analysis of structure and dynamics of refraction in 147 children (238 eyes) with retinopathy of prematurity of I-III stage during initial years of life under the type of "longitudinal section" at 6, 12, 18 and 24 months of life.
It was detected that during all the studied age periods myopia was the prevailing type of abnormal refraction in children with retinopathy of prematurity and its incidence decreased from 73.7% at 6 months to 60.5% at 24 months. Incidence of myopia including high myopia was significantly higher in the group of induced regression in comparison with the group of spontaneous regression (76 and 28.2% respectively).
In children with retinopathy of prematurity instability of refraction during the initial years of life is a feature of refractogenesis, which may change both towards amplification and attenuation of refraction.
Myopia formation in premature infants occurs against the background of eyeball growth retardation after premature birth; at that the lens and the cornea play the leading role in myopia development.


  1. Катаргина Л. А., Коголева Л. В., Мамакаева И. Р. Состояние рефракции у детей с РН первых 2 лет жизни // Рос. офтальмол. журн. - 2009. - Т. 2, № 3. - С. 25-28.
  2. Коголева Л. В., Хватова А. В., Катаргина Л. А. Особенности рефракции у детей с ретинопатией недоношенных // Близорукость, нарушения рефракции, аккомодации и глазодвигательного аппарата: Материалы симпозиума. - М., 2001. - С. 269-270.
  3. Connolly B. P. et al. Comparison of laser photocoagulation with cryotherapy for threshold retinopathy of prematurity at 10 years. Part 2. Refractive outcome // Ophthalmology. - 2002. - Vol. 109, N 5. - P. 936-940.
  4. Fledelius H. C. Retinopathy and myopia of prematurity // Br. J. Ophthalmol. - 2000. - Vol. 84, N 8. - P. 937.
  5. Gordon R. A., Donzis P. B. Myopia association with ROP // Ophthalmology. - 1986. - Vol. 93. - P. 1593-1598.
  6. Holmstrom G. M. el Azazi, Kugelberg U. Ophthalmological long term follow up of preterm infants: a population based, prospective study of the refraction and its development // Br. J. Ophthalmol. - 1998. - Vol. 82. - P. 1265-1271.
  7. Kais Algavi, Goggin M., O'Keefe M. Refractive outcome following diode laser versus cryotherapy for eyes with retinopathy of prematurity // Br. J. Ophthalmol. - 1994. - Vol. 78. - P. 612-614.
  8. Quinn G. E. et al. Development of myopia in infants with birth weights less than 1251 grams // Ophthalmology. - 1992. - Vol. 99, N 3. - P. 329-328.



Abstract - 19


Article Metrics

Metrics Loading ...


  • There are currently no refbacks.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies