DRY EYE SYNDROME ASSOCIATED WITH ENDOGENOUS UVEITIS IN THE CHILDREN

Abstract


A total of 47 children with uveitis of different localization and etiology were available for the estimation of overall lacrimation and stability of the precorneal lacrimal film. The study demonstrated a high frequency of dry eye syndrome (DES) diagnosed in 85% of the patients suffering the moderately or strongly impaired lacrimation and stability of the precorneal lacrimal film (in 46% and 28% of the cases respectively). The multi-factor character of dry eye syndrome was documented. Its development was shown to be related to the frequency of relapses of uveitis, the presence of a systemic rheumatoid disease, local anti-inflammatory and hypotensive therapy, systemic immunosuppressive treatment, and/or surgical interventions on the anterior parts of the eyes. DES was shown to be associated with the dystrophic changes in the cornea. The necessity of early diagnostics of dry eye syndrome in the patients presenting with uveitis and of prescription of tear replacement therapy is substantiated.

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About the authors

L. A Katargina

Moscow Helmholtz Research Institute of Eye Diseases


Yu. P Shestova

Moscow Helmholtz Research Institute of Eye Diseases


E. V Denisova

Moscow Helmholtz Research Institute of Eye Diseases


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