A total of 47 children with uveitis of different localization and etiology were available for the estimation of overall lacrimation and stability of the precorneal lacrimal film. The study demonstrated a high frequency of dry eye syndrome (DES) diagnosed in 85% of the patients suffering the moderately or strongly impaired lacrimation and stability of the precorneal lacrimal film (in 46% and 28% of the cases respectively). The multi-factor character of dry eye syndrome was documented. Its development was shown to be related to the frequency of relapses of uveitis, the presence of a systemic rheumatoid disease, local anti-inflammatory and hypotensive therapy, systemic immunosuppressive treatment, and/or surgical interventions on the anterior parts of the eyes. DES was shown to be associated with the dystrophic changes in the cornea. The necessity of early diagnostics of dry eye syndrome in the patients presenting with uveitis and of prescription of tear replacement therapy is substantiated.

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About the authors

L. A Katargina

Moscow Helmholtz Research Institute of Eye Diseases

Yu. P Shestova

Moscow Helmholtz Research Institute of Eye Diseases

E. V Denisova

Moscow Helmholtz Research Institute of Eye Diseases


  1. Бржеский В.В., Сомов Е.Е. Роговично-конъюнктивальный ксероз (диагностика, клиника, лечение). — 2-е изд. — СПб., 2003.
  2. Карагулян Н.А. Особенности поражения глаз у детей с хроническими болезнями печени: Автореф. дис.. канд. мед. наук. — М., 2006.
  3. Akinci A., Cetinkaya E., Aycan Z. Dry eye syndrome in diabetic children // Eur. J. Ophthalmol. — 2007. — Vol. 17, N 6. — P. 873—878.
  4. Alves M., Dias A.C., Rocha E.M. Dry eye in childhood: epidemiological and clinical aspects // Ocul.Surf. — 2008. — Vol.6, N 1. — P. 44—51.
  5. El-Shazly A.A., Mohamed A.A. Relation of dry eye to disease activity in juvenile rheumatoid arthritis // Eur. J.Ophthalmol. — 2012. — Vol. 22, N 3. — P. 330—334.
  6. Fahnehjelm K.T., Törnquist A.L., Winiarski J. Dry-eye syndrome after allogeneic stem-cell transplantation in children // Acta Ophthalmol. — 2008. — Vol. 86, N 3. — P. 253—258.
  7. Kotaniemi K.M., Salomaa P.M., Sihto-Kauppi K. et al. An evaluation of dry eye symptoms and signs in a cohort of children with juvenile idiopatic arthritis // Clin. Ophth. — 2009. — Vol. 3. — P. 271—275.
  8. Kurpiúska M., Gorczyúska E., Owoc-Lempach J. et al. Assessment of lipid layer thickness of tear film in the diagnosis of dry-eye syndrome in childrenafter the hematopoietic stem cell transplantation // Klin.Oczna. — 2011. — Vol. 113, N 4—6. — P. 136—140.
  9. Lemp M.A., Ralph R.A. Rapid development of band keratopathy in dry eyes // Am. J. Ophthalmol. — 1977. — Vol. 83, N 5. — P. 657—659.
  10. Lipiec E., Gralek M., Niwald A.The dry eye syndrome in children with juvenile idiopatic arthritis // Klin.Oczna. — 2008. — Vol. 110, N 1—3. — P. 35—39.
  11. MacCord Medina F., Silvestre de Castro R., Leite S.C. et al. Management of dry eye related to systemic diseases in childhood and longterm follow-up // Acta Ophthalmol Scand. — 2007. — Vol. 85, N 7. — P 739—744.
  12. Mrugacz M., Minorowska A., Bakunowicz-Lazarczyk A., Zywalewska N. Dry eye syndrome in children with cystic fibrosis // Med. Wieku. Rozwoj. — 2004. — V. 8, N 4. — P. 865—870.



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