THE DEVELOPMENT OF THE RATIONAL SCHEME FOR THE APPLICATION OF DERINAT EYE DROPS, 0.25%, IN THE COMBINED TREATMENT OF EXPERIMENTAL OPHTHALMOHERPES

Abstract


The authors report the results of the experimental evaluation of the efficacy of a new parmaceutical dosage form of derinat eye drops. The study was carried out using the experimental rabbit model of ophthalmoherpes. In the first series of experiments, the therapeutic efficacy of derinat eye drops, 0.25%, was compared with that of 3% zovirax eye ointment. It was shown that derinat produced a well-apparent therapeutic effect comparable with that of zovirax. The clinical efficacy of combined therapy with derinat and zovirax with different intervals between the applications of either preparation was estimated in the 2 nd and 3d series of experiments. It is concluded that it is important to strictly comply with the prescribed intervals (2 hours) between the applications of the tested medications.

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About the authors

E. R Stirmanova

Moscow Helmholtz Research Institute of Eye Diseases

Email: stirman@mail.ru

A. I Shchipanova

Moscow Helmholtz Research Institute of Eye Diseases


L. A Katargina

Moscow Helmholtz Research Institute of Eye Diseases


References

  1. Егоров Е.А., Сугоняева О.Ю. Клиническое применение препарата Деринат — Интернет-журнал «Офтальмология для всех» http://www.oftalm.ru/
  2. Каплина Э.Н., Вайнберг Ю.П. Деринат — природный иммуномодулятор для детей и взрослых. 3-е изд. — М., 2007.
  3. Кузин В.Б., Соколова Т.П. Послеоперационная иммунокоррекция деринатом препролиферативной диабетической ретинопатии после пенретинальной лазеркоагуляции // Казан. мед. журн. — 2009. Т. 90, № 4. — С. 575—577.
  4. Майчук Ю.Ф. Вирусные заболевания глаз. — М., 1981.
  5. Применение Дерината в офтальмологии: Пособие для практикующих врачей. 2-е изд. / Под ред. Э.Н. Каплиной, Н. О. Бажанова. — Тверь, 2008.
  6. Щипанова А.И., Майчук Ю.Ф., Стирманова Е.Р. и др. Медико-биологическая оценка новой глазной лекарственной формы отечественного препарата Деринат // Рос. офтальмол. журн. — 2012. — Т. 5, № 2. С. 88.

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