Hemangioma treatment efficiency of the combined orbital and periorbital areas in infants

Abstract


This research was designed to evaluate the efficiency and safety of the orbital and periorbital areas hemangiomas’ combined conservative treatment in 105 infants. Hormone and radiotherapy used in 37 children, 33 children received only radiotherapy, 35 children underwent surgical intervention. The average age was 17,5±6,8 months. Radiotherapy was performed fractionally, single doses varied from 0.3 Gy to 1.7 Gy. Total number of fractions depended on tumor size and its rate of growth, nearly 5-8 per course, total tumor dose ranged from 8 to 12 Gy. It was demonstrated that previous surgical and parasurgical intervention lead to radiotherapy poor starting conditions, treatment prolongation, increase total radiation dose. This study shows a high clinical efficiency of hemangiomas’ combined treatment using radio- and hormonal therapy, good cosmetic effect and reducing of complications incidence. The use of these approaches in hemangiomas’ treatment is characterized by more rapid process completing, which is obviously due to the high radiosensitivity of infantshemangiomas.

Full Text

Restricted Access

About the authors

V. V Neroev

The Helmholtz Moscow Research Institute of Eye Diseases


S. G Berejnova

The Helmholtz Moscow Research Institute of Eye Diseases

Email: berejnova.s@yandex.ru

W. W Walskiy

The Helmholtz Moscow Research Institute of Eye Diseases


References

  1. Подлящук Е.Л. Лучевое лечение гемангиом наружных покровов у детей. Радиология - практика. 2008; 1: 41-7.
  2. Abry F., Kehrli P., Speeg-Schatz C. Hemangioma of the eyelids and orbit in children: therapeutic follow-up. J. Fr. Ophtalmol. 2007; 30 (2): 170-6.
  3. Chik K.K., Chan H.B., Tan H.Y. Use of propranolol in infantile haemangioma among Chinese children. Hong Kong Med. J. 2010; 15 (5): 341-6.
  4. Aldo Stamm J. F. N. Orbital cavernous hemangioma: Transnasal endoscopic management. Otolaryngology Head Neck Surg. 2009; 141: 794-5.
  5. Batniji R.K., Williams E.F. An aesthetic approach to facial hemangiomas. Arch. Facial Plast. Surg. 2005; 7 (5): 301-6.
  6. Вайнштейн Е.С., Бурдянская Е.И., Подлящук Е.Л. Отдаленные результаты рентгенотерапии ангиом орбитальной области и прилежащих к ней участков лица у детей. Офтальмологический журнал. 1982; 2: 71-5.
  7. Буторина А.В. Современное лечение гемангиом у детей. Лечащий врач. 1999; 5: 61-4.
  8. Plesner-Rasmussen H., Goldschmidt E. Capillary haemangiomas of the eyelids and orbit. Acta Ophthalmol. 1983; 61: 645-54.
  9. Manju E., Jacobson J., Simon S., Amy Jo Nopper. Adverse effects of systemic glucocorticosteroid therapy in infants with hemangiomas. Arch. Dermatol. 2004; 140: 963-9.
  10. El-Dessouky M., Raine P.A., Young D.G. Kasabach-Merritt syndrome. J. Pediatr. Surg. 1988; 23: 109-11.

Statistics

Views

Abstract - 6

PDF (Russian) - 0

Cited-By


Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies