Russian Pediatric OphthalmologyRussian Pediatric Ophthalmology1993-18592412-432XEco-Vector3744910.17816/rpoj37449Research ArticleEYE CHANGES IN THE CHILDREN PRESENTING WITH TUBEROUS SCLEROSISMosinI. Meyes.mosin@mail.ruBalayanI. G-YarkinaO. S-NeudakhinaE. A-BeslaneevaM. B-RasulovaS. G-1503201271293221072020Copyright © 2012, Eco-Vector2012The results of ophthalmologic examination of 119 children aged from 6 months to 18 years presenting with tuberous sclerosis are reported. Changes in the eyes were documented in 75.4% of the patients. Astrocytic hamartomas of the retina were found in 53.8% of the children. Punched-out areas of retinal depigmentation were seen in 43% of the patients with tuberous sclerosis compared with 4% healthy children. In the disputable situations, the finding of the depigmented spots can be regarded as a diagnostic criterion suggesting tuberous sclerosis. Abnormal refraction and heterophthalmia were documentd in 58% and 17.3% of the children with tuberous sclerosis respectively. These disorders were responsible for the persistent visual impairement due to visual deprivation. It is concluded that the correction of ametropia and heterophthalmia constitutes an important treatment modality for the rehabilitation of the children presenting with tuberous sclerosis.tuberous sclerosisretinal hamartomaтуберозный склерозгамартома сетчатки[Мосин И.М.Факоматозы // В кн.: Наследственные и врожденные заболевания сетчатки и зрительного нерва. Под ред. Шамшиновой А. М. - М., 2001. - С. 325-351.][Темин П.А., Новиков П.В., Дорофеева М.Ю. Туберозный склероз // В кн.: Наследственные нарушения нервно-психического развития детей. Под ред. Темина П. А., Казанцевой Л. 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