Vol 8, No 1 (2013)

Articles
PECULIARITIES OF BLOOD CIRCULATION IN THE ORBITAL VESSELS OF THE CHILDREN PRESENTING WITH CONGENITAL MICROPHTHALMOS OF DIFFERENT SEVERITY
Neroev V.V., Sudovskaya T.V., Kiseleva T.N., Kruzhkova G.V., Makarova A.A., Kokoeva N.S.
Abstract
We have determined characteristics of hemodynamics in the orbital vessels of 26 children presenting with congenital unilateral microphthalmos of different severity using the duplex scanning technique in the colour doppler flow mapping regime and pulsed dopplerography. The study revealed hemodynamic disturbances in the ophthalmic artery, central retinal artery, and short posterior ciliary arteries. The blood flow velocity was significantly reduced while the resistance index (RI) increased compared with the respective normal values in the ophthalmic artery, central retinal artery, and short posterior ciliary arteries. The severity of hemodynamic disturbances in the orbital vessels showed positive correlation with the degree of microphthalmos and the frequency of detection of the concomitant eye pathology affecting in the first place retina and optic nerve.
Russian Pediatric Ophthalmology. 2013;8(1):4-7
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THE RETROSPECTIVE ANALYSIS OF THE APPLICATION OF HYPOTENSIVE MEDICATIONS FOR THE TREATMENT OF CONGENITAL GLAUCOMA IN THE CHILDREN BASED AT A PEDIATRIC SURGICAL DEPARTMENT
Katargina L.A., Tarasenkov A.O., Mazanova E.V.
Abstract
The authors present their many-year experience with the application of modern hypotensive medications for the treatment of various forms of congenital glaucoma in the children depending on the stage of pathology and the degree of its compensation. The data obtained were used to estimate the effectiveness of antiglaucoma agents belonging to different pharmacological groups and propose the algorithm for medicamental therapy of congenital glaucoma in the children including young ones.
Russian Pediatric Ophthalmology. 2013;8(1):8-12
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PECULIARITIES OF THE SURGICAL TREATMENT OF CONGENITAL CATARACTS WITH THE USE OF INTRAOCULAR LENS IMPLANTATION IN THE PATIENTS PRESENTING WITH CONGENITAL MALFORMATIONS OF THE POSTERIOR LENS CAPSULE
Kruglova T.B., Egiyan N.S., Kononov L.B.
Abstract
We have developed a differential technology for the surgical treatment of congenital cataracts and associated congenital changes of the shape and transparency of the posterior lens capsule. The method allows to perform intraocular lens (IOL) implantation even in the presence of the well-apparent posterior lenticonus, avoid the development of intraoperative and postoperative complications, and thereby improve the quality of rehabilitation of the patients presenting with congenital cataract and concomitant lens malformations.
Russian Pediatric Ophthalmology. 2013;8(1):12-15
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THE RESULTS OF THE APPLICATION OF HISTOCHROME IN THE CHILDREN PRESENTING WITH ACTIVE RETINOPATHY OF PREMATURITY
Demchenko E.N., Belyaeva I.A., Katargina L.A.
Abstract
This paper is designed to report the results of the application of histochrome for the treatment of the children presenting with «pre-plus» disease and concomitant active retinopathy of prematurity. The preparation was administered intramuscularly in the form of a 0.02% solution. The effectiveness criteria included the time between the onset of the disease and the development of its threshold stage, the area of avascular retina by the time of emergence of the threshold stage, and the frequency of spontaneous regression and beneficial outcomes of retinopathy of prematurity. The results of histochrome injections given to 25 children (50 eyes) were compared with those obtained in the control group comprised of 16 children (32 eyes). The patients of both groups were matched not only for somatic parameters but also for the severity of clinical symptoms of retinopathy of prematurity. It was shown that histochrome injections to the children exhibiting large areas of avascular retina at the stages of pre-retinopathy, pre-threshold plus-disease, and pre-plus disease (1) increased the frequency of spontaneous regression of the pathological process (to 44.0% compared with 12.5% in controls) and (2) slowed down its development into the threshold stage (the period from the onset of manifestations of retinopathy of prematurity to the threshold stage was as long as 0.7-9 (mean 4.11 ± 0.57) weeks compared with 0.6-3.5 (mean 2.28 ± 0.19) weeks in controls. Taken together, these changes promoted the reduction of the area of avascular retina by the time of laser coagulation. As a result, the cicatrical changes in the subsequent period were less pronounced. Moreover it allowed to postpone the surgical intervention till the child becomes older and therefore is at a lower risk due to the less aggravated somatic condition. (3) Finally the effectiveness of laser coagulation was enhanced.
Russian Pediatric Ophthalmology. 2013;8(1):15-17
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BIOMECHANICAL CHARACTERISTICS OF THE CORNEOSCLERAL TUNIC AND THE STATE OF THE CONNECTIVE TISSUE SYSTEM IN THE CHILDREN AND ADOLESCENTS PRESENTING WITH VARIOUS FORMS OF PROGRESSIVE MYOPIA
Iomdina E.N., Tarutta E.P., Markosyan G.A., Aksenova Y.M., Kruzhkova G.V., Ivashchenko Z.N., Smirnova T.S., Bedretdinov A.N.
Abstract
Moscow Helmholtz Research Institute of Eye Diseases The present comprehensive study was designed to evaluate the biomechanical characteristics of the corneoscleral tunic and the state of the connective tissue system in 155 children and adolescents at the age varying from 9 to 17 (mean 13.4 ± 2.1) years differing in terms of clinical refraction for the development of informatively valuable diagnostic criteria for the compromised supportive function of the sclerotic coat in the patients presenting with congenital and acquired forms of progressive myopia with the complicated or uncomplicated clinical course. It was shown that the local biochemical abnormalities associated with progressive myopia (such as reduced corneal hysteresis and scleral acoustic density) are associated with general manifestations of connective tissue dysplasia, relatively reduced cortisol level, and disturbed balance of the vegetative nervous system (an increased absolute value of the Kerdo index). Congenital myopia and myopia with the complicated clinical course are characterized by some specific features of the aforementioned abnormalities that must be taken into consideration in diagnostics and prognostication of further development of the disease. It is recommended that the Kerdo index and the articular hypermobility index readily accessible to measurement in the framework of the routine ophthalmological examination should be used as the additional criteria for monitoring the clinical symptoms of myopia, the choice of the treatment strategy for individual patients (including indications for subsequent sclerotherapy), and assessment of its effectiveness.
Russian Pediatric Ophthalmology. 2013;8(1):18-23
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RETINAL ASTROCYTIC HARMATOMA: TWO CLINICAL CASES, VISUALIZATION WITH THE HELP SPECTRAL OPTICAL COHERENT TOMOGRAPHY
Myakoshina E.B.
Abstract
Two clinical cases of retinal astrocytic harmatoma (calcified and non-calcified forms) are presented that illustrate the important role of spectral optical coherent tomography in diagnostics of this pathology.
Russian Pediatric Ophthalmology. 2013;8(1):23-27
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CLINICAL CHARACTERISTICS AND THE RESULTS OF KERATOPLASTY IN THE CHILDREN PRESENTING WITH CONGENITAL CORNEAL OPACIFICATION AND CONCOMITANT CONGENITAL GLAUCOMA
Pleskova A.V., Mazanova E.V., Katargina L.A.
Abstract
This paper is focused on the specific clinical, anatomical, and functional characteristics of different forms of combined pathology including congenital glaucoma and congenital corneal opacification (of non-glaucomatous etiology). These conditions were revealed with the use of such highly informative method for the examination of the anterior parts of the eye as ultrasound biomicroscopy (UBM). The results of analysis of biological and functional outcomes of the surgical treatment by means of penetrating keratoplasty are presented. The method is applicable to the treatment of the young children differing in the degree of manifestations of the changes in the anterior parts of the eye.
Russian Pediatric Ophthalmology. 2013;8(1):27-30
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SUPERSELECTIVE INTRA-ARTERIAL CHEMOTHERAPY FOR THE TREATMENT OF REFRACTORY AND ADVANCED RETINOBLASTOMA: POSSIBLE COMPLICATIONS AND MEASURES FOR THEIR PREVENTION
Saakyan S.V., Zharua A.A., Myakoshina E.B., Lazareva L.A., Yakovlev S.B.
Abstract
The potential local and systemic complications of superselective intra-arterial chemotherapy used to treat refractory and advanced forms of retinoblastoma are considered in conjunction with the currently available measures of their prevention. In addition, possible causes of unsuccessful outcomes of this treatment modality are discussed.
Russian Pediatric Ophthalmology. 2013;8(1):31-34
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THE DIAGNOSTIC CRITERIA FOR HABITUALLY-EXCESSIVE ACCOMMODATION STRAIN BASED ON SUBJECTIVE AND OBJECTIVE CHARACTERISTICS OF ACCOMMODATION
Tarutta E.P., Tarasova N.A.
Abstract
The subjective and objective parameters of habitually-excessive accommodation strain (HEAS) were estimated in 130 patients at the age varying from 6 to 18 (mean 11.26 ± 0.2) years presenting with myopia of different severity. The patients were divided into 3 groups depending on the difference between subjectively assessed refraction (using the corrective glass) and objective cycloplegic refraction. It was shown that the enhancement of the subjective non-cycloplegic refraction compared with the objective cycloplegic one by more than 0.5 dioptres is accompanied by the highest rate of myopia progression, significantly higher values of accommodation strain (resting accommodation strain), habitual accommodation strain, open-field habitual accommodation strain), and accommodation deficiency (the reduction of all subjective and objective characteristics of accommodation performance). The results of the study give reason to consider habitual accommodation strain, i.e. the difference between manifest and cycloplegic refraction of more than 0.5 dioptres, as the diagnostic criterion for habitually-excessive accommodation strain (HEAS). This difference is possible to calculate from the comparison of cycloplegic refraction and the pre-cycloplegic refraction obtained by means of subjective correction or based on the readings of one and the same autorefractomer or from the data of remotometry.
Russian Pediatric Ophthalmology. 2013;8(1):34-38
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THE CYTOKINE PROFILE IN THE PATIENTS PRESENTING WITH THE EARLY MANIFESTATIONS OF PRIMARY OPEN-ANGLE GLAUCOMA
Cherednichenko L.P., Barycheva L.Y., Bernovskaya A.A.
Abstract
Stavropol State Medical Academy This study included a total of 70 patients of whom 25 presented with suspected glaucoma, 25 with the initial stage of glaucoma, and 20 with advanced stages of the disease. All the patients were found to have the increased levels of IFN-γ, IL-1β, and TNF-α in the lacrimal fluid and blood sera depending on the severity of glaucoma. Moreover, advanced glaucoma was associated with the enhancement of IL-17 in the lacrimal fluid. The patients with glaucoma exhibited the predominantly Th-1 variant of the immune response. Switching to the Th2 variant occurred at the later stages of the pathological process.
Russian Pediatric Ophthalmology. 2013;8(1):38-42
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CHILDREN’S EYE PROTECTION IN THE BRYANSK REGION
Poltavtsev A.V., Paramei O.V., Maksimova N.V.
Abstract
This paper describes the structure and organization of the children’s eye protection services in the Bryansk region and their diagnostic and therapeutic potential for the provision of specialized ophthalmological aid to the child population. The principal medico-statistical characteristics of ophthalmological health in the Bryansk region are compared with those in the Russian Federation at large. The authors propose the measures for the improvement of the eye protection services for the children in the Bryansk region.
Russian Pediatric Ophthalmology. 2013;8(1):43-45
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THE ROLE OF TONOMETRY IN THE MANAGEMENT OF CERVICAL SPINE OSTEOCHONDROSIS
Cherednichenko L.P., Borisova L.I.
Abstract
The present literature review concerns hydrodynamics and the development of concomitant disorders in the patients suffering cervical spine osteochondrosis. Roughly 40% of such patients present with a moderate reduction of intraocular pressure at the affected side as evidenced by the results of clinical examination, computed and magnetic resonance tomography and neuropathological examination. These observations are consistent with the data on the pathogenetic mechanisms underlying this pathology. In the majority of the patients, reduction of intraocular pressure is associated with lens dilatation and retinal pallor revealed during eye ground ophthalmoscopy as well as other pathological manifestations caused by disturbed innervations, insufficiency of cerebral circulation and ischemia. It is concluded that these symptoms may be regarded as ophthalmological signs of cervical spine osteochondrosis.
Russian Pediatric Ophthalmology. 2013;8(1):46-48
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CONTRIBUTING TO THE DISCUSSION OF THE PAPER «CLASSIFICATION OF CONGENITAL CATARACTS» BY N.F. BOBROVA
Kruglova T.B., Khvatova A.V.
Abstract
Russian Pediatric Ophthalmology. 2013;8(1):49-49
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THE ALGORITHM OF SURGICAL INTERVENTION AND MEDICAMENTAL TREATMENT OF DACRIOCYSTITIS IN THE NEWBORN INFANTS
Arestova N.N., Katargina L.A.
Abstract
The many-year experience with the treatment of more than 3,000 young children provided a basis for the development of the algorithm for the treatment of congenital pathology of the tear passages (dacriocystitis of newborn infants, atresia of the nasolacrimal duct, dacriocystocele) taking into consideration the patients’ age. The main forms of the surgical intervention are described in conjunction with the principles of medicamental therapy at different stages of the treatment.
Russian Pediatric Ophthalmology. 2013;8(1):50-52
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THE ROLE OF THE «LUTEIN COMPLEX FOR CHILDREN» IN THE TREATMENT OF EYE DISEASES
Guseva M.R., Sidorenko E.I., Markova E.Y., Matveev A.V., Uchaeva N.S.
Abstract
Russian Pediatric Ophthalmology. 2013;8(1):53-65
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OCULAR TOXOCAROSIS IN THE CHILDREN
Kuvaitseva N.G., Mikhailova M.G.
Abstract
Ocular toxocarosis in the children is currently a challenging problem in pediatrics. This paper is devoted to the description of several cases of this pathology encountered in our clinical practice.
Russian Pediatric Ophthalmology. 2013;8(1):65-67
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A CASE REPORT OF POSTERIOR KERATOCONUS IN A 11-YEAR OLD CHILD
Seliverstova K.E., Vakhova E.S.
Abstract
This paper reports a clinical case of newly diagnosed unilateral localized posterior keratoconus in a 11-year old girl that was initially diagnosed as the corneal ulcer threatening perforation. The present case is interesting in that the diseases passed unnoticed by the child and that the marked thinning of the cornea did not result in its perforation.
Russian Pediatric Ophthalmology. 2013;8(1):67-69
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The III World Congress on retinopathy of prematurity
Kogoleva L.V.
Abstract
Russian Pediatric Ophthalmology. 2013;8(1):69-70
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Our jubilee. Celebrating the 35 th anniversary of the Children’s Consultative Outpatient Clinic at the Helmholtz Moscow Research Institute of Eye Diseases
Kharlampidi M.P., Sudovskaya T.V.
Abstract
Russian Pediatric Ophthalmology. 2013;8(1):71-72
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