Journal of Volgograd State Medical UniversityJournal of Volgograd State Medical University1994-94801994-9499Volgograd State Medical University118759Research ArticleNORMAL SIZE VALUES FOR FETAL CISTERNA MAGNA IN SECOND TRIMESTER OF PREGNANCYKozlovaO. I.olesya_poberii@mail.ru1504201411411912016122022Copyright © 2014, Kozlova O.I.2014Fetal brain was retrospectively evaluated in 385 normal fetuses at 16-27 weeks of gestation. A multiplanar brain reconstruction mode was used to obtain the axial cerebral plane which passes through the cerebellum. All measurements were performed from the posterior aspect of the cerebellum to the inner surface of the occipital bone. The key research findings showed that the depth of the cisterna magna tends to increase during the second trimester and makes up 2.8 (range 2,1-4,3) mm at 16/0-16/6 weeks to 6.4 (range 4,4-8,4) mm at 26/0-26/6 weeks. The established percentile depth values for the fetal cisterna magna (mean, 5 th and 95 th percentile) can be used to assess normal fetal brain development while performing ultrasound in the second trimester of pregnancyfetussecond trimestercisterna magnaultrasound examinationплодвторой триместр беременностибольшая цистернаультразвуковое исследование[Медведев М. В. Основы ультразвукового скрининга в 18-21 неделю беременности. 2-е изд., доп. и перераб. - М.: Реал Тайм, 2013. - С. 55.][Медведев М. В., Алтынник Н. А., Лютая Е. Д. // Вестник Волгоградского государственного медицинского университета. - 2012. - № 3 (43). - С. 41-43.][Сапин М. Р., Бочаров В. Я., Никитюк Д. Б. и др. Анатомия человека. - 5-е изд., доп. и перераб. - М.: Медицина, 2001. - Т. 2. - 454 с.][Lai T. H., Cheng Y. M., Chang F. M. Prenatal diagnosis of trisomy 21 in a fetus with an enlarged cisterna magna // Ultrasound Obstet. Gynecol. - 2002. - Vol. 20. - P 413-416.][Mahony B. S., Callen P. W., Filly R. A., Hoddick W. K. The fetal cisterna magna // Radiology. - 1984. - Vol. 153. - P 773-776.][Quarello E., Molho M., Garel C., et al. Prenatal abnormal features of the fourth ventricle in Joubert syndrome and related disorders // Ultrasound Obstet. Gynecol. - 2014. - Vol. 43. - P 227-232.][Salomon L. J., Stirnemann J., Bernard J., et al. Cisterna magna measurements in normal fetuses in relation to gestational age and other covariables // Ultrasound Obstet. Gynecol. - 2010. - Vol. 36 ( Suppl. 1). - P. 52-167.][Sonographic examination of the fetal central nervous system: guidelines for performing the 'basic examination' and the 'fetal neurosonogram' // Ultrasound Obstet. Gynecol. - 2007. - Vol. 29. - P 109-116.][Steiger R. M., Porto M., Lagrew D. C., Randall R. Biometry of the fetal cisterna magna: estimates of the ability to detect trisomy 18 // Ultrasound Obstet. Gynecol. - 1995. - Vol. 5. - P 384-390.]