Journal of Volgograd State Medical UniversityJournal of Volgograd State Medical University1994-94801994-9499Volgograd State Medical University11935310.19163/1994-9480-2019-1(69)-96-99Research ArticleCYTOLOGICAL METHOD OF RESEARCH IN THE DIAGNOSIS AND TREATMENT OF LICHEN PLANUS OF THE ORAL MUCOSAPoroiskyS. Bporoyskiy@mail.ruFirsovaI. Vinfo@eco-vector.comMakedonovaYu. Ainfo@eco-vector.comPoroiskayaA. V.info@eco-vector.comFedotovaYu. Minfo@eco-vector.comFSBEI HE «Volgograd State Medical University» of Public Health Ministry of the Russian Federation15012019161969918122022Copyright © 2019, Poroisky S.B., Firsova I.V., Makedonova Y.A., Poroiskaya A.V., Fedotova Y.M.2019<p>One of the common inflammatory and destructive diseases in gerontostomatology is lichen planus. The course of this pathology is long, persistent and chronic. Early methods of diagnosing the disease, timely pharmacotherapy are the key to success in the treatment of lichen planus. Cytological method of research refers to the methods by which you can quickly get the results and adjust the scheme of drug symptomatic treatment of erosive and ulcerative lesions in the oral cavity. It is based on the study of the structural features of cellular elements. In this work, we examined and treated 60 patients with erosive-ulcerative form. In 30 people, in addition to traditional treatment, Titol's applications with a 0,1 % betamethasone solution are included in the scheme of complex therapy; in the second half of the patients, applications of betamethasone, fixed using a mucoadhesive polymer film, are used. In the resulting scrapings under magnification of x400 and x1000, the evaluation of the stage of destruction of epithelial cells with the corresponding morphological characteristic was made. In both cases, a positive trend was noted, however, the cytological picture was different depending on the type of drug therapy.</p>lichen planuscytologybetamethasoneTizolкрасный плоский лишайцитологиябетаметазонТизоль[Анисимова И.В., Недосеко В.Б., Ломиашвили Л.М. Клиника, диагностика и лечение заболеваний слизистой оболочки рта и губ. - М.: Мед. книга; Изд-во «Стоматология», 2008. - С. 130.][Быкова И.А., Агаджанян А.А., Банченко Г.В. Цитологическая характеристика отпечатков слизистой оболочки полости рта с применением индекса дифференцировки клеток // Лабораторное дело. - 1987. - № 1. -С. 33-35.][Деформация эритроцитов: роль в микроциркуляции / А.В. Муравьёв, В.Л. Комлев, П.В. Михайлов с соавт. // Ярославский педагогический вестник. - 2013. - № 2. -Том III (Естественные науки). - С. 93-102.][Дмитриева Л.А. Терапевтическая стоматология. Национальное руководство. - М.: ГЭОТАР-Медиа, 2009. -894 с.][Македонова Ю.А., Поройская А.В., Фирсова И.В., Поройский С.В. Оптимизация местной терапии больных красным плоским лишаем слизистой полости рта // Пародонтология. - 2017. - № 4 (85). - С. 30-34.][Oral lichen planus: a report and review of an autoimmune-mediated condition in gingiva / G. Pendyala, S. Joshi, J. Kalburge et al. // Compend. Contin. Educ. Dent. - 2012. -Sep. 33, № 8. - Р. 102-108.][Oral lichen planus: Focus on etiopathogenesis / M.R. Payeras, K. Cherubini, M.A. Figueiredo et al. // Arch. Oral. Biol. - 2013. - № 9. - Р. 52.][Poroiskiy S.V., Makedonova Yu.A., Firsova I.V., Poroiskaya A.V., Trigolos N.N. Experimental morphologic study of reparative processes in erosive lesions of the oral mucosa // General Dentistry. - 2018. - № 66 (4). -Р. 5-9.][Tar I. The oral lichen planus: doubts and evidence / I. Tar, I. Marton // Fogorvosi Szemle. - 2009. - Vol. 102, № 3. - Р. 103-109.][Torrente-Castells E. Clinical features of oral lichen planus. A retrospective study of 65 cases / Е. Torrente- Castells // Medicina Oral, Patologfa Oral Y Cirugfa Bucal. - 2010. - Vol. 15, № 5. - Р. 685-690.]