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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pharmateca</journal-id><journal-title-group><journal-title xml:lang="en">Pharmateca</journal-title><trans-title-group xml:lang="ru"><trans-title>Фарматека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-4034</issn><issn publication-format="electronic">2414-9128</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">277188</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">New targets of treatment of patient from the risk group for vascular complications of atherosclerosis</article-title><trans-title-group xml:lang="ru"><trans-title>НОВЫЕ ЦЕЛИ ЛЕЧЕНИЯ БОЛЬНОГО ИЗ ГРУППЫ РИСКА СОСУДИСТЫХ ОСЛОЖНЕНИЙ АТЕРОСКЛЕРОЗА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zateyshchikov</surname><given-names>D A</given-names></name><name xml:lang="ru"><surname>Затейщиков</surname><given-names>Д А</given-names></name></name-alternatives><bio xml:lang="ru"><p>ФГУ Учебно-научный медицинский центр УД Президента РФ, Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Zateishikov</surname><given-names>D A</given-names></name><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ФГУ Учебно-научный медицинский центр УД Президента РФ, Москва</institution></aff></aff-alternatives><aff id="aff2"><institution></institution></aff><pub-date date-type="pub" iso-8601-date="2009-05-20" publication-format="electronic"><day>20</day><month>05</month><year>2009</year></pub-date><volume>16</volume><issue>10</issue><issue-title xml:lang="en">NO10 (2009)</issue-title><issue-title xml:lang="ru">№10 (2009)</issue-title><fpage>10</fpage><lpage>14</lpage><history><date date-type="received" iso-8601-date="2023-02-22"><day>22</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2009, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2009, ООО «Бионика Медиа»</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/2073-4034/article/view/277188">https://journals.eco-vector.com/2073-4034/article/view/277188</self-uri><abstract xml:lang="en"><p>Based on the results of recent studies of statins (JUPITER, etc.) discussed the potential positive therapeutic effects (anti-inflammatory, antithrombotic) of this group medicine that could be grounds for revision of guidance for their use. Emphasized the importance of the statins impact on C-reactive protein (CRP), given the fact that the latter is an active participant in atherothrombosis. We showed that the relatively healthy people with high CRP levels treated with active statin, had not only myocardial infarction or stroke risk reduction, but also frequency reduction of thromboembolic complications and death from cancer. The author believes that the statins administration in the normalization of CRP should be another factor tracked during treatment, in addition to the level of low density lipoprotein.</p></abstract><trans-abstract xml:lang="ru"><p>На основании результатов последних исследований статинов (JUPITER и др.) обсуждаются потенциальные позитивные лечебные эффекты (противовоспалительные, антитромботические) этой группы лекарственных средств, которые могут стать основанием для пересмотра рекомендаций по их применению. Подчеркивается важность воздействия статинов на С-реактивный белок (СРБ, с учетом того, что последний является активным участником атеротромбоза. Указывается, что у относительно здоровых людей, имеющих повышенный уровень СРБ, назначение активного статина приводит не только к снижению риска инфаркта миокарда или инсульта, но и к уменьшению частоты тромбоэмболических осложнений и смерти от онкологических заболеваний. По мнению автора, при назначении статинов нормализация уровня СРБ должна стать еще одним фактором, отслеживаемым во время лечения, в дополнение к уровню липопротеидов низкой плотности.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Complications of atherosclerosis</kwd><kwd>statins</kwd><kwd>rozuvostatin</kwd><kwd>C-reactive protein</kwd><kwd>low-density lipoprotein</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Осложнения атеросклероза</kwd><kwd>статины</kwd><kwd>розувостатин</kwd><kwd>С-реактивный белок</kwd><kwd>липопротеиды низкой плотности</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Jialal I, Devaraj S, Venugopal SK. C-Reactive protein: risk marker or mediator in atherothrombosis? Hypertension 2004;44(1):6-11.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Ridker PM, Rifai N, Pfeffer A, et al. 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